Request InfoLinkam Scientific Instruments Ltd.Linkam Scientific Instruments has developed a stage for cryo-correlative light electron microscopy (cryo-CLEM) used in imaging of cells at cryo temperatures. It was designed in collaboration with Leiden University Medical Centre. Cryo-CLEM is the correlation of images captured with a cryo stage on a fluorescent light microscope and images of the same sample observed with transmission electron microscopy (TEM). The correlative stage is being used as part of a work flow that starts with cells expressing cancer-related genes and ends with imaging in synchrotrons located in Oxford,...See full productRelated content from Photonics MediaPRODUCTSPromoted Content April 2024 IssueLife Science Imaging SolutionsAdvanced imaging solutions for OEM instrument makers and researchers pushing the limits of microscopy in life science. Developing new diagnostic methods, tools and technologies? Contact Navitar or...Promoted Content April 2024 IssueGet More Data: Automate Your MicroscopeZaber offers a selection of standard and customized motorized microscope stage products. They offer: Exceptional Performance Maximize your throughput and consistency with up to 500-nm...Promoted Content March 2024 IssueUltra-Precision Microscopy DemoThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...Promoted Content February 2024 IssueOEM-Ready Microscope SubsystemsThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...ARTICLESBioPhotonics.com March 2024 IssueAI and Laser Tech Automate Rapid Sorting and Analysis of Live CellsTo realize the potential of personalized medicine and overcome crisis situations like the recent pandemic, labs need an efficient way to isolate living cells for analysis and testing. The ability to...Photonics.com 10/24/2023Fluorescence Lifetime Imaging Could Improve Cancer Surgery OutcomesExtreme precision is required to surgically remove a cancerous tumor without damaging the surrounding healthy tissue. Yet surgeons often must rely on their eyes and hands to determine where to cut....BioPhotonics Jan/Feb 2024 IssueMicroscopy Method Detects Treatment-Resistant CancerTherapy-induced senescent (TIS) cells are cancer cells that become resistant to therapies and enter a dormant stage. These cells can emerge from dormancy and induce tumor resistance and relapse. To...Photonics.com 1/25/2024Optofluidic Device Tests for Blood Disorders at Point of CareAbnormalities in white blood cell count are indicative of a blood disorder. Measuring these abnormalities is imperative. However, the use of flow cytometry and other conventional methods to assess...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookCamera Resolution: Combining Detector and Optics PerformanceCamera resolution depends upon the optical blur diameter and the detector size. Schade combined these to create an equivalent resolution that is a function of Fλ/d where F is the focal ratio,...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 9/12/2022Ingenuity + Instrumentation: Creating a Novel 4D Microscopy MethodTracking particles at the micro or nanoscale is inherently difficult due to the complexity of the systems studied, as well as the technical challenges: a blend of instrument design, photonics,...Photonics.com 2/16/2024Rapid Automated Modular MicroscopeOverview of Rapid Automated Modular Microscope.Photonics.com 4/28/2023“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...WEBINARSPhotonics.com 6/9/2016Photonics for OphthalmologyPhotonics Media invites you to join us for our upcoming FREE digital conference, "Photonics for Ophthalmology." The event will feature several 15-minute online presentations on the use of light-based...Photonics.com 10/27/2022Reconstituted Beam Helps to Classify Cancerous Tissue in Space-Time Light-Sheet MethodDiouf discusses his team’s investigations of the self-healing (self-reconstituting) capabilities of the space-time light sheet when it interacts with a partially transparent object,...Photonics.com 9/29/2022A Technical Exploration of Spatial Light Modulators and Their Latest 3D ApplicationsLASER COMPONENTS brings together some of the brightest minds in the industry for a one-hour workshop. Doctoral students from MIT, Princeton University, and Stanford University share how they are...Photonics.com 12/14/2011The Future of Imaging: Three PerspectivesPresenters: Professor Stephen Boppart The Future of Healthcare With Optical Biomedical Imaging A medical doctor and professor at the University of Illinois, Boppart's...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryintravital microscopyIntravital microscopy is an imaging technique used to visualize biological processes within living organisms, typically in real-time. Unlike traditional microscopy, which involves the examination of...Photonics Dictionarynanoparticle photonic resonator absorption microscopyNanoparticle photonic resonator absorption microscopy is a microscopy technique that combines the principles of photonic resonators and nanoparticle imaging to visualize and study biological samples...Photonics Dictionaryfluorescence lifetime imagingFluorescence lifetime imaging (FLIM) is an advanced imaging technique that provides information about the lifetime of fluorescence emissions from fluorophores within a sample. Unlike traditional...Photonics Dictionaryreflectance confocal microscopyReflectance confocal microscopy (RCM) is a non-invasive imaging technique that allows for high-resolution, in vivo imaging of biological tissues at the cellular level. It is particularly useful in...VIDEOSPhotonics.com 1/18/2018Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...Photonics.com 1/18/2018Supporting the Photonics Industry from the Laboratory - LIGHT MATTERS 01.2018On this month's episode of Light Matters, we take you to central Massachusetts as Worcester Polytechnic Institute and Quinsigamond Community College take on a comprehensive joint photonics laboratory...Photonics.com 11/16/2018Luminate NY 2019: Lightning AwardsLuminate is the world's largest Optics, Photonics and Imaging accelerator focused on advancing next-generation OPI-enabled companies. The accelerator program accepts ten companies per year to compete...Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...PHOTONICS BUYERS' GUIDE CATEGORIESPhotodynamic Therapy/Oncology Laser SystemsMicroscope LensesUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Telephoto LensesTelephoto lenses is a compound lens so constructed that its overall length is equal to or less than its effective focal length.COMPANIESPhotonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...Photonics Buyers' GuideFOCtek Photonics Inc.FOCtek provides customers with all types of custom manufactured lenses, Precision Optical Components, Polarizing Optics, Prisms, Filters, Coatings, Optical Systems, Crystals, Nonlinear Crystals,...Photonics Buyers' GuideReynard CorporationReynard Corporation has been a premier supplier of custom optics and thin-film coatings to a global customer base since 1984. Reynard focuses on manufacturing the highest quality products with...