ITHACA, N.Y., June 12 -- A new imaging technique that could lead to optical biopsies without removal of tissue is being reported by biophysical scientists at Cornell and Harvard universities. The advance in biomedical imaging enables noninvasive microscopy scans through the surface of intact organs or body systems. Demonstrations of the new technique are producing images of diseased tissue at the cellular level with unprecedented detail, according to a Cornell statement. Diagnoses of cancers and neurodegenerative diseases, such as Alzheimer's disease, are two applications suggested by the...Read full articleRelated content from Photonics MediaArticlesNobel Prize-Winning Techniques Help Resolve Imaging ChallengeUsing a technique that was recently awarded the 2022 Nobel Prize in chemistry, researchers at Cornell University used expansion microscopy to study lipids, the water-repellent, dynamic components...BioPhotonics Jan/Feb 2023 IssueCompanies Partner on Biomedical Image Data Capture, ProcessRaw image compression company Dotphoton will partner with Hamamatsu Photonics to make accessible higher-quality image data contained within biomedical images, such as those obtained through...BioPhotonics Jul/Aug 2022 IssueImaging System Speeds Diagnosis with Real-Time Biopsy AnalysisResults of a pilot study conducted at the University of Rochester showed that a system based on two-photon fluorescence microscopy (TPFM) enabled rapid diagnosis of nonmelanoma skin cancer through...Photonics.com 10/13/2022Biophotonics Congress 2023 Centers on Cell Labeling in Diagnostics and Superresolution MicroscopyResearchers and systems designers with expertise in techniques such as signal and image processing for biomedical optics and optical manipulation of the nervous system will converge April 24-27 at...BioPhotonics Mar/Apr 2023 IssueProductsPhocuscan - A New Concept SPCMAs photocurrent mapping emerges as a popular technique for material analysis applications, Nanobase introduces a stand-alone scanning photocurrent microscope dubbed “Phocuscan.” Phocuscan...Photonics Showcase December 2023 IssueCW Diode-Pumped LaserHÜBNER Photonics has released a higher power model of the Cobolt Jive™ 561-nm laser on the 05-01 series platform. With up to 1000-mW continuous wave output power, the laser can be...BioPhotonics Jul/Aug 2023 IssueMicroscopy SoftwareSuite SIX software from WITec GmbH is designed for Raman and correlative measurement control, data acquisition, and post-processing. The software offers multiple user profiles, regulatory compliance...BioPhotonics Sep/Oct 2023 IssueAI MicroscopeThe APEXVIEW™ APX100 All-in-One Microscope from Evident Corp. provides publication-quality images for life science research. Featuring Olympus optics, intuitive software, artificial...BioPhotonics Sep/Oct 2022 IssuePhotonics Handbook ArticlesNSOM: Discovering New WorldsNSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...Photonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal MicroscopyWhen evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...Photonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookWhite PapersIs a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 4/20/2023Photoluminescence Spectroscopy of Carbon DotsCarbon dots (C-dots) are nanoparticles composed of carbon with diameters below 10 nm. They were accidentally discovered in 2004 by Xu, et al1 when researching methods to purify carbon nanotubes....Photonics.com 8/17/2022“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...Photonics.com 4/28/2023Optical Filters and LED IlluminationUnderstanding the interplay of optical filters, microscope light source and fluorophore selection can be a complex task, especially when it comes to multi-channel imaging. However, the selection of...Photonics.com 6/16/2022WebinarsFull-Field Optical Coherence TomographyOptical coherence tomography (OCT) is an interferometric imaging technique that has become an established tool for deep-tissue imaging. Full-field (FF) OCT is one of its variants that can perform...Photonics.com 10/28/2021Quantitative Stimulated Raman Scattering Microscopy: From Molecules to AnimalsStimulated Raman scattering (SRS) microscopy has become a powerful chemical imaging tool that shows significant promise in numerous biological and biomedical applications. In a typical SRS microscopy...Photonics.com 2/14/2023Seeing the Sound: Optical Neural Interfaces for In Vivo NeuromodulationOptogenetics has transformed experimental neuroscience by manipulating the activity of specific cell types with light, enabling in vivo neuromodulation with millisecond temporal resolution. Visible...Photonics.com 1/6/2021Advanced Optoacoustic and Fluorescence Techniques for Noninvasive Scalable Imaging of Mammalian BrainNeuroscience has a fundamental need for more efficient and less intrusive ways to observe the activity of large distributed neuronal populations and related vascular changes at multiple spatial and...Photonics.com 10/28/2021Photonics Dictionary Termsnonlinear optical materialsNonlinear optical materials are substances that exhibit optical properties that are not linearly proportional to the intensity of incident light. In other words, these materials produce optical...Photonics DictionaryBose-Einstein condensateA Bose-Einstein condensate (BEC) is a state of matter that forms at temperatures close to absolute zero. It is named after Satyendra Nath Bose and Albert Einstein, who independently predicted the...Photonics DictionaryoptoacousticOptoacoustic, or photoacoustic, refers to a phenomenon and related techniques that involve the generation of acoustic waves in a material induced by the absorption of light. The term "optoacoustic"...Photonics Dictionaryhyperspectral imaging cameraA hyperspectral imaging camera is a sophisticated imaging device capable of capturing and processing data across a wide range of wavelengths within the electromagnetic spectrum, typically from...Photonics DictionaryMediaApplied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 5/2/2022Andor Solutions - Accelerating Scientific AdvancementsGround-breaking products that enable hassle-free, high-quality research across life and physical sciences.Photonics.com 11/20/2023Photographic Lighting & Molecular Signatures - LIGHT MATTERS 07.23.2014On this week’s show, a drone aids photographic lighting, a sensor diagnoses diabetes, fluorescence detects Alzheimer’s and a sensor amplifies molecular signatures.Photonics.com 7/23/2014Capasso Group Revolutionizes Flat LensesResearchers at the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a single flat lens that can focus the entire visible spectrum of light in the same spot and in...Photonics.com 7/5/2018Photonics Buyers' Guide CategoriesPolarizing MicroscopesPicosecond LasersConfocal MicroscopesMicroscope CamerasCompaniesAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideAvantes BVAvantes has spent the last 30 years refining its mission as a trusted and innovative optical instruments and solutions source. Focused on applications and measurements, Avantes offers Spectrometers,...Photonics Buyers' GuideSmarAct Inc.Since 2005, SmarAct develops piezo-based, high-performance positioners and measurement tools for the micro- and nanometer scale. Positioning systems with numerous degrees of freedom and parallel...Photonics Buyers' Guide