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BioPhotonics - February 2012
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Issue Library
Features
3-D Microscopy Goes Deeper and Deeper
New systems take researchers inside the workings of tissue, cells, organelles The biomedical industry is constantly involved in biological research and development, not only examining the basic functions of cells and tissues to find targets for therapeutic intervention, but also testing new and existing drugs. Microscopy has been an essential tool for the pharmaceutical industry for many...
SPR Provides a Boost to Drug Discovery and Development
Surface plasmon resonance techniques show promise as the new standards of drug discovery, especially for treating cancer. In the realm of drug discovery, the hunt is ever on for new combinations of...
Piezoelectric Actuation Adds Capabilities for Microscopy
Microscopy is a broad field – and it is getting broader every week, as novel imaging techniques are brought to bear to illuminate the nanoscale world. These techniques are enabled and assisted...
Vision Inspection Systems Keep Meds Safe
One place you don’t want a mix-up is in pharmaceutical packaging – label one pill as another, and a life-threatening disaster could ensue. That means that the vision system on the...
Terahertz Techniques Reveal the Hidden World of Pharmaceuticals
Advances in terahertz imaging and spectroscopy are making it easier for pharmaceutical researchers and manufacturers to predict crystal structures of common and uncommon drugs as well as to...
Editorial
Changing the World One Photon at a Time
“This is a room filled with problem solvers, and this world is filled with problems that optics can solve biomedically.” – R. Rox Anderson, MD, co-chairman, BiOS Symposium So began the BiOS Hot Topics session at SPIE Photonics West in January, where roughly 1000 audience members heard about breakthroughs and challenges on subjects ranging from early cancer detection with...
BioScan
Sparking neurons help scientists understand brain signals
Neurons that light up as they fire are providing researchers with a better picture of how signals travel within the brain. The genetically altered neurons use a gene from a Dead Sea microorganism to...
New drug makes brain tumors glow hot pink
An experimental drug that glows hot pink when illuminated with a special blue light from an operating microscope can identify the difference between tumors and healthy tissue, improving tumor...
Laser ablation benefits precancerous skin lesions
Carbon dioxide laser ablation could be an alternative treatment for lentigo maligna (LM) when surgery or radiation therapy is not feasible. Carbon dioxide laser ablation may be the most advantageous...
Nanophotonic endoscope looks inside single living cells
A new nanophotonic endoscope can take high-resolution images of the inside of a single living cell and deliver therapeutic drugs and other cargo without injuring or damaging the cell. Lawrence...
Label-free bioimaging tool tracks nanotubes
A new imaging tool tracks carbon nanotubes inside living cells and throughout the bloodstream – and it could soon hone the particles’ usefulness in biomedical research and clinical...
Cell race turns science into spectator sport
Learning more about how cells move is vitally important to cancer research as well as in areas such as embryonic development and human growth. But the serious nature of the work does not mean it...
New tissue phantoms help with imaging-device design
A novel combination of additives enables gelatin to acquire optical and acoustical properties that accurately match soft tissue in humans. These tissue mimics, or phantoms, provide an accurate...
Laser imaging assesses sunscreen safety
A new laser imaging technique could help answer safety questions surrounding nanoparticles by assessing the risks associated with zinc oxide (ZnO), a sunscreen ingredient. Although ZnO...
RapidScan
Gated STED pushes boundaries of superresolution microscopy
Superresolution microscopy is about to take a big step forward, thanks to a licensing agreement among Leica Microsystems, the Max Planck Society and the German Cancer Research Center. Leica will develop new stimulated emission depletion (STED) microscopes to observe molecule movements within living cells’ membranes. The instruments will use a new method from Dr. Stefan Hell, director...
Affymetrix Inc.
In California, Affymetrix Inc. of Santa Clara has signed a definitive agreement to acquire eBioscience Inc. of San Diego for $330 million in cash, subject to certain customary adjustments. The...
Austriamicrosystems
Austriamicrosystems of Unterpremstätten, Austria, is supplying high volumes of intelligent ambient light and proximity sensors for four Samsung Galaxy smartphone models. The sensors, which are...
Newport Corp.
To avoid cash interest payments, Newport Corp. of Irvine, Calif., retired $69.6 million of its 2.5% convertible subordinated notes due Feb. 15, 2012, for a sum of $70 million plus accrued interest....
Gooch & Housego
Optical and systems manufacturer Gooch & Housego of Somerset, UK, will lead the collaborative €4.5 million (about $5.9 million) European Union-funded FP7 project ISLA (Integrated disruptive...
Applied Precision Inc.
Applied Precision Inc. of Issaquah, Wash., is set to integrate enhanced total internal reflection fluorescence (TIRF) microscopy into its product line now that is has licensed new technology patents...
IPG Photonics
IPG Photonics of Oxford, Mass., will add 175 employees as part of an $18 million plan to expand its facility by more than 100,000 sq ft, with the help of $1.7 million in tax credits from the state of...
Incom Inc.
Fused fiber optics components maker Incom Inc. of Charlton, Mass., has announced its expansion into the polymer fiber optics market with the acquisition of 11413%%Paradigm Optics, a maker of polymer...
Ametek Inc.
Electronic instruments maker Ametek Inc. of Berwyn, Pa., has acquired privately held Technical Manufacturing Corp. (TMC) of Peabody, Mass., a manufacturer of vibration isolation systems and optical...
Modulight Inc.
Revenue for 2011 was up 10 percent over 2010 for laser manufacturer Modulight Inc., according to President and CEO Petteri Uusimaa. The company, based in Tampere, Finland, attributes its growth to...
Precision Optical
Laser-quality precision optical assemblies and components manufacturer Precision Optical of Costa Mesa, Calif., celebrated the opening of its 42,000-sq-ft state-of-the-art facility in December....
PhotOral
Boston-based life sciences startup PhotOral has licensed patented technology from Forsyth Institute of Cambridge, Mass., to develop an intraoral device that uses blue light for targeting and...
SPIE
The first SPIE Britton Chance Biomedical Optics Award has been given to Robert Alfano, distinguished professor of physics at City College of New York. The award will be presented annually to honor...
Postscripts
The bold and the beautiful – on the microscale
Microscopic imaging is not just about science; it can be an art, too. The microscale world is breathtaking, comical and strange, and the winning images from the 2011 Olympus BioScapes Digital Imaging Competition show off scientists’ efforts to capture not only data but also the beauty of that tiny world. Taking fifth prize in the competition is this image of live green brain coral...
Products
Green Lasers for Surgery
Power Technology Inc. has launched a green-wavelength version of its PM series laser module. Designed for medical and surgical applications, it performs better than red lasers on dark-colored or pigmented skin and on red tissue, the company says. Green-wavelength lasers also are easier to identify under the bright light conditions in the operating room. The PM visible laser diode module is...
Power Technology Inc.
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Scientific CMOS Camera
Hamamatsu Photonics has introduced the ORCA-Flash4.0 scientific CMOS camera. Featuring good quantum efficiency, low noise, high resolution and fast readout, it delivers better signal-to-noise...
Hamamatsu Photonics UK Ltd.
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Digital Cameras
For bright-field and fluorescence microscopy imaging applications, Olympus Europa Holding GmbH has released the ultra-resolution DP73 and DP73WDR digital cameras. The multipurpose microscope cameras...
Olympus Europa SE & Co. KG
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Microscope Photometer
For photometric analysis of microscopic samples in biology, geology and cytophotometry, Craic Technologies Inc. has launched the MP-2 microscope photometer. The rugged all-solid-state system measures...
CRAIC Technologies
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Optical Oxygen and pH Sensors
For monitoring of food and fermentation processes, Ocean Optics Inc. has produced optical oxygen and pH sensors. The fiber optic sensors are designed for accurate in situ measurements in various...
Ocean Optics - Part of Ocean Insight
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NIR Line-Scan Camera
The Piranha HS (high sensitivity) near-infrared 8k line-scan camera manufactured by Teledyne Dalsa has enhanced quantum efficiency and features time delay and integration (TDI) technology. The camera...
Teledyne DALSA, Machine Vision OEM Components
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Surface Imaging Software
Digital Surf sarl’s MountainsMap 6.2 surface imaging and metrology software integrates Chinese GB/T standard references for surface texture parameter families, extending the “right...
Digital Surf
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Digital Color Sensors
TAOS has announced the TCS3x71 and TCS3x72 digital color RGB sensors with an infrared blocking filter and a proximity sensor. The sensors provide color measurement and, when coupled with an IR LED,...
AMS-TAOS USA Inc.
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NIR Single-Photon Counter
Aurea Technology is launching the SPD_B, a single-photon-counting module for shortwave near-infrared wavelengths from 1000 to 1350 nm. The ultralow-noise, high-quantum-efficiency device includes a...
AUREA Technology
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Active Coherence Stabilization
Toptica Photonics Inc.’s BlueMode diode laser family now includes GreenMode and RedMode. The new models deliver high power and high coherence from a single diode across the visible spectrum....
TOPTICA Photonics Inc.
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Variable Field Module
For applications with MFP-3D atomic force microscopes (AFMs), Asylum Research has introduced the variable field module2 (VFM2), intended for researchers who want to apply magnetic fields to their...
Oxford Instruments Asylum Research
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Scientific CMOS Camera
For high-speed live-cell fluorescence imaging applications, QImaging announces the Rolera Bolt scientific CMOS camera. Designed for low-light applications, it is suitable for biomedical imaging as...
Teledyne QImaging, Teledyne Imaging
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Spectroradiometers
ASD Inc.’s FieldSpec 4 line of portable spectroradiometers is designed for fast, precise spectral data collection. The instruments operate from 350 to 2500 nm and allow researchers to cover...
ASD Inc.
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Ultrafast Laser
The Vitara from Coherent Inc. is a widely tunable ultrafast laser that delivers pulse widths shorter than 12 fs. It offers hands-free and fully automated operation, including automated wavelength...
Coherent Inc.
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AFM Platform
Anasys Instruments Corp. has launched the afm+ fully integrated atomic force microscopy (AFM) platform, which offers important analytical capabilities. Using thermal probe technology for nanoscale...
Anasys Instruments Corp.
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Viewing Cabinet
The compact, lightweight CM-10MP mini viewing cabinet manufactured by Spectronics Corp. is suitable for life science applications that require high-contrast fluorescence analysis, for viewing...
Spectronics Corp., Spectroline
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QI for AFM System
JPK Instruments has announced new quantitative imaging (QI) capabilities for the recently launched NanoWizard 3 atomic force microscopy (AFM) system. The QI mode was developed by the company to...
Bruker Nano GmbH, JPK BioAFM
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Wavelength Extender
Newport Corp. has introduced the SCG-02 wavelength extender to its line of nonlinear microscopy and spectroscopy application solutions. It is a modular solution for supercontinuum generation when...
MKS/Newport
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Polymer Measurement
B&W Tek Inc. and Gnosys Global Ltd. have released PolymerIQ software for accurate, real-time, nondestructive identification and quantification of polymers. Combining B&W Tek’s i-Raman...
B&W Tek LLC
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Multichannel Framing Cameras
Specialised Imaging’s multichannel framing cameras (SIM) are ultrahigh-speed instruments that provide wide application flexibility to university research groups. Using high-resolution image...
Specialised Imaging Inc.
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TERS-Ready AFM System
Bruker Corp.’s Nano Surfaces Div. has introduced the Innova-IRIS integrated system for correlated atomic force microscopy (AFM) and Raman spectroscopic imaging. Its ultralow closed-loop noise,...
Bruker Nano Surfaces
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