Olympus Europa Holding GmbH’s cellSens deconvolution module employs a constrained iterative algorithm to remove out-of-focus blur in advanced life sciences imaging. This high-speed operation provides sharp images and near confocal quality, and corrects for spherical aberrations. Integrating seamlessly with the cellSens Dimensions software, it delivers high performance and quality. Using a specialized and improved algorithm developed for the company, the module provides high-speed image restoration. Maximizing modern PC computing capabilities, it leverages multicore processor architectures to provide powerful deconvolution, sharpening even the blurriest images. Users obtain fast and comprehensive results, without the complex parameter adjustment steps required with other de-blurring algorithms.