WITec GmbH has introduced an extension of its alpha300 microscope series. Building on the system’s inherent modularity, the company has added several new microscope versions to meet diverse customer requirements. In the field of Raman microscopy, the new baseline is the micro Raman system alpha300 M for single-point spectrum acquisitions and depth profiling. The alpha300 M+ is additionally equipped with a stepper motor and enables Raman mapping experiments and large-area investigations. The stepper motor can also be attached to the alpha300 R Raman imaging system, providing a flexible and powerful research tool (alpha300 R+) for automated large-area and high-resolution 3-D chemical imaging. The alpha300 ML features cost-effective high-resolution confocal Raman mapping for high spectral flexibility in the UV/VIS/NIR regions.