Solentim Ltd. has announced the Cell Metric cell imaging and analysis instrument. Engineered as a high-throughput work flow system to screen for colonies from single-cell cloning experiments, it uses proprietary nonimage-based focusing to locate all possible colonies by imaging the whole well, right up to the edge. The platform provides complete and accurate cell measurements, without removing the cells from the culture plate and without adding stains or dyes, ensuring that cells are suitable for use in downstream experiments. The system can identify every healthy viable cell clone from large multiwell screening projects and can track the visual history of the colonies back to single cells. The proprietary imaging technology overcomes the problems of shadowing and edge effects. Colonies tend to form around the edge of wells.