Manufactured to be extremely flat (±15 μm across the base), Krystal glass-bottom microplates from Porvair Sciences Ltd. are suitable for use in whole-plate CCD imaging and laser detection applications. Available in 24-, 96- and 384-well formats, the microplates combine the benefits of the optical properties of glass – low background and low birefringence – with the versatility of a microplate. According to the company, they demonstrate higher performance than standard polystyrene plates for fluorescence assays, luminescence detection, scintillation counting and high-resolution microscopy using confocal imaging. They are available tissue culture-treated or without surface modification. The high-clarity bottom of each plate offers exact positioning when used with microscopes. Based upon a standard SBS/ANSI microplate format, they are compatible with automated liquid handling and robotic devices.