Request InfoNikon Instruments Inc.The new Ti-diSPIM module from Nikon Instruments Inc. gives light-sheet imaging capabilities to the company’s flagship Ti inverted research microscope. Selective plane illumination microscopy (SPIM) minimizes phototoxicity and photobleaching in imaging of live specimens. A thin sheet of light is used to illuminate a focal plane of the cell that is coincident with the focus of the imaging lens. This also provides optical sectioning by not illuminating out-of-focus regions, which would normally result in image blur. 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