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  • Cobolt Optogenetics Laser Solutions

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Cobolt Optogenetics Laser SolutionsCobolt offers a range of high performance, reliable and user friendly laser assemblies specially tailored for advanced Optogenetics research. The laser assemblies have been developed in close collaboration with leading Optogenetics research laboratories and offer experiment-ready solutions for configurable solutions for channelrhodopsin activation and halorhodopsin inhibition.

Cobolt’s Optogenetics solutions include single-line lasers with stable and efficient coupling into multimode fibers, two lasers on a common platform launched into one common fiber coupler or two lasers sitting side by side launched into one fiber each, suitable for 2-into-1 coupling using e.g. fused fibers. The lasers are available at various wavelengths matching the sensitivity peaks of the commonly used Rhodopsins, with adjustable optical output power up to 100 mW and fast high aspect ratio modulation with perfect pulse control.

Each configuration starts with a highly reliable and very stable Cobolt laser. The MLD Series lasers are compact laser diode modules that can be directly modulated and feature precision electronics. The MLD Series is the preferred 473nm laser for optogenetics. The 04-01 Series of diode-pumped solid-state (DPSS) lasers enables laser excitation at wavelengths unattainable with laser diodes, in particular 594nm and 561nm. These lasers are designed for continuous wave output and do not typically permit high fidelity modulation.

To achieve precision modulation, Cobolt offers the 04-05 Series lasers with integrated acousto-optic modulator (AOM) in the same package with a 04-01 DPSS laser.

Configurations include single lasers or two lasers combined into a single multi-mode fiber (MM), lasers with or without intensity modulation capability and stand-alone lasers or assemblies with fiber couplers. To each fiber-coupled system, a MM fiber (with 50µm-200µm core diameter) of your choice can be easily attached.

All packages offer full control over the pulse generation, perfect pulse-to-pulse stability, high extinction ratio and fiber coupling efficiencies of up to 80%.


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A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of cells...
acousto-optic modulator
A device that varies the amplitude and phase of a light beam; e.g., from a laser or by sound waves. Also known as a Bragg cell.
single-line laser
A laser whose output is limited to a single wavelength.
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