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FRET News
Flow Cytometry Technique Shows Promise for Early Cancer Diagnosis
GUANGDONG, China, Sept. 8, 2022 — A digital droplet microfluidic flow cytometry technique could enable earlier recognition of tumor development and progress, by aiding in the detection of multiple microRNAs (miRNAs) in single circulating tumor cells (CTCs). Tumor-associated miRNAs...
Scientists Confirm Dynamin Molecular Motor’s Constriction Mechanism
KANZAWA, Japan, Sept. 3, 2021 — A team at Kanzawa University used the measurement technique of single-molecule fluorescence resonance energy transfer, or smFRET, as well as a computable model, to develop a method that determined the strength of an individual dynamin motor....
In Vivo Imaging with FLIM Shows Effect of Experience on Neuronal Activity
JUPITER, Fla., Dec. 30, 2019 — Every day, the neuronal connections within our brains change depending on what we learn and experience in our daily lives. Specialized proteins, called activity-dependent transcription factors, activate genes within the cells of the brain to help it...
FRET Offers Real-Time Look at HIV Infection Process
NEW YORK and WASHINGTON, Oct. 14, 2014 — Scientists can now study the motion of HIV proteins on the surface of the virus, opening new possibilities for fighting the disease.
Fluorescent Tool Shows Nanoparticles Biodegrade in Real Time
PHILADELPHIA, April 29, 2014 — A recent study using Förster resonance energy transfer (FRET) to chart the disintegration of nanoparticles in living tissue in real time could aid the development of safe nano-drug delivery methods. “Nanoparticles are made with very...
Diatom Biosensor Could Detect Chemicals in Water
SEQUIM, Wash., March 30, 2012 — A biosensor made of fluorescent proteins that are embedded in the shell of microscopic marine algae called diatoms could help detect chemicals in water samples. The device could help produce nanomaterials that can solve sensing, catalysis and...
Multimodal Imaging: Combining Techniques to Give Microscopists a Boost
May 24, 2011 — On the way to conjoining two well-established but disparate imaging modalities, a FLIM (fluorescence lifetime imaging) and CARS microscope was achieved along with the development of an adapter that could bring real change to the way microscopists...
Wegner Named ‘2011 Young Investigator’
SAN FRANCISCO, Feb. 24, 2011 — David Wegner has been named as the winner of the SPIE 2011 Young Investigator Award, which is sponsored by Ocean Optics of Dunedin, Fla. The Young Investigator Award is presented to the researcher — no more than five years out of school...
Quantum Dots: Applications for Artificial Atoms Expanding
Feb 23, 2011 — The use of quantum dots is nearly ubiquitous in Förster’s resonance energy transfer (FRET), but scientists are just beginning to scratch the surface on other applications for the semiconductor nanocrystals, such as in biosensors and as a way...
Microscope Aids Study of Single Molecules
AMES, Iowa, Nov. 29, 2010 — By combining atomic force microscopy (AFM) and Förster resonance energy transfer (FRET) technologies, a researcher at Iowa State University has developed new approach toward single-molecule microscopy. Sanjeevi Sivasankar was looking for a...
FRET Tracks Single Enzyme
CHAMPAIGN, Ill., Sept. 20, 2010 — Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme. Helicase enzymes are best known for “unzipping” DNA for...
Grant to Fund Single-Molecule Microscope
AMES, Iowa, Sept. 3, 2010 — An Iowa State University researcher received a state grant to develop an instrument that reveals single molecules. Sanjeevi Sivasankar, an assistant professor of physics and astronomy, demonstrates a microscope he's developing that can reveal...
An Optogenetic Guide to the Brain
WAKO, Japan, July 20, 2010 — Scientists at RIKEN have developed a genetically encoded fluorescent sensor that can act as a direct optical indicator of signaling activity in the living brain. This powerful tool, described in a new article from Nature Methods, promises to help...
Donors and Acceptors: New Developments in FRET
Sep 1, 2009 — Förster resonance energy transfer, or FRET, has contributed to advances in a host of applications and the development of the technique is ongoing. In recent years, FRET has benefited from a variety of new components and methodologies. In this Web...
Technology: Achieving Multiplexed FRET
Jan 1, 2009 — Förster resonance energy transfer, or FRET, provides a means to study the temporal dynamics of protein interactions by measuring the transfer of energy between donor and acceptor molecules. Researchers label two molecules of interest with a...
McMaster Lab Protein Study Targets Huntington's
HAMILTON, Ontario, Feb. 28, 2007 -- A new bioimaging facility at McMaster University is shedding light on how kinase inhibitors might prevent the protein that causes Huntington's disease from accumulating in the nucleus of brain cells, which could ultimately lead to a treatment for...
FRET Technique Developed to Observe DNA-Repairing Protein
CHAMPAIGN, Ill., Aug. 15, 2006 -- Researchers have observed the life cycle of RecA, a protein that plays a major role in repairing damaged DNA, by using a highly sensitive, single-molecule fluorescence resonance energy transfer (FRET) technique they developed . A better...
Biotech Startup Granted $1.65M for 'Molecular Beacon'
ATLANTA, July 31, 2006 -- A company co-founded by a Georgia Institute of Technology researcher has received a $1.65 million federal grant to develop and commercialize a nanoscale sensor called a “molecular beacon” for the detection and diagnosis of diseases including cancer....
(18 results found)
May 2024
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