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drug delivery News
Light-Activated Tool Controls Protein Bonds and Tracks Cell Adhesion
TAMPERE, Finland, Nov. 20, 2023 — Optical tools can be used to activate biological functions, but with current methods the effects are slow to appear, and sustained effects require continuous light activation. As a result, these light-activation tools provide limited control of fast biological processes and can lead to toxicity in cells and organisms. Although light is a well-established tool for control of bond breakage, it is less firmly established for the control of specific bond formation in complex
Low-Power Optical Tweezers Protect Bioparticles from Damage
AUSTIN, Texas, Nov. 10, 2023 — Optical tweezers trap and manipulate minute particles with light. The technology is used across fields, ranging from manufacturing to biotech, though it requires the use of high-powered lasers to ensure proper function. These lasers can damage the...
Pump-Probe Spectroscopy Could Help to Control Chiral Molecules
BERLIN, Dec. 30, 2022 — An international research team at Freie Universität Berlin, in collaboration with colleagues at the DESY research center, Kiel University, and Kansas State University, has proposed a quantum-chemical calculation-based approach to induce and...
Light-Activated Molecular Motors Achieve Fluorescence
GRONINGEN, Netherlands, Nov. 14, 2022 — In their study of rotary molecular motors, researchers in the laboratory of Ben Feringa at the University of Groningen have combined two light-mediated functions — motion and fluorescence — within a single molecule. The advancement is...
Microsize Molecular Machines Swarm for Drug Delivery
SAPPORO, Japan, April 25, 2022 — Scientists at Hokkaido University demonstrated light-manipulated microsize molecular machines, or robots, that performed cargo delivery through a swarming strategy to ultimately achieve a transport efficiency 5× greater than that of single...
Method Keeps Liquid Marbles Functional for Microfluidic Systems
NATHAN, Australia, March 11, 2022 — A research team from Griffith University developed a technique that uses condensation to noninvasively refill liquid marbles with water. The method could improve the viability of applications such as drug delivery. According to the researchers, the...
PerkinElmer to Acquire BioLegend
WALTHAM, Mass., July 26, 2021 — PerkinElmer (PE) will make the largest transaction in its history. The company has entered into an agreement to acquire BioLegend, a global provider of life science antibodies and reagents, in a deal worth approximately $5.25 billion. The deal is...
Titanium Oxide Challenges Gold Standard Photoporation Method
TOYOHASHI, Japan, Jan. 27, 2021 — Researchers in the mechanical engineering department at Toyohashi University of Technology (TUT) have developed a low-cost photoporation method using titanium-oxide nanotubes. Photoporation is a technique that relies on focused light to perforate...
UV-Powered Fluid Pump Could Move Pollutants, Deliver Drugs
STATE COLLEGE, Pa., Jan. 23, 2019 — A highly controllable method that uses UV light to control particle motion and assembly within liquids could be used in drug delivery, chemical sensors, and fluid pumps. Developed by the Sen Lab at Pennsylvania State University, the new technique...
Lasers and Machine Vision Improve Pharma Manufacturing
Mar 1, 2015 — Through pill marking, quality assurance and more, laser-based manufacturing processes and machine vision make medications safer for consumers and more profitable for pharmaceutical companies. In the multidisciplinary pharmaceutical industry,...
Gold nanoprobes + FRET = cancer insights
GLASGOW, Scotland – Gold nanoprobes paired with FRET (Förster resonance energy transfer) microscopy could allow researchers to study cancer cells in more minute detail and measure the effectiveness of medicines at subcellular levels. Gold nanoparticles have...
Gold Probes Offer Insight into Cancer
GLASGOW, Scotland, June 25, 2013 — Gold nanoprobes paired with FRET microscopy could yield a new generation of biological imaging and sensing techniques capable of studying cancer cells in minute detail, measuring the effectiveness of medicines at subcellular levels and identifying...
Erupting ‘Nanovolcanoes’ For Drug Delivery
RALEIGH, N.C., June 14, 2013 — “Nanovolcanoes” carved out of a synthetic polymer with UV light can store and release precise amounts of materials, a feat suitable for drug-delivery technologies, its creators say.
Light-Controlled Gel Could Benefit Soft Robots
BERKELEY, Calif., June 4, 2013 — Inspired by the way plants grow toward light sources, bioengineers at the University of California, Berkeley, created a hydrogel that flexes in response to near-IR laser light. The achievement could be a step toward adding softness and flexibility...
New QDs address biocompatibility
Apr 1, 2013 — Quantum Materials Corp. (QMC) has developed a class of cadmium-free, nonheavy metal tetrapod quantum dots (NHM-TPQDs) to address global concerns regarding nanoparticle biocompatibility and sustainability. “While our cadmium-based...
Microactuator flexes under laser light
BERKELEY, Calif. – A microscale actuator that flexes like a tiny beckoning finger under a burst of laser light may point toward practical applications in artificial muscles, microfluidics and drug delivery. The Lawrence Berkeley National Laboratory (Berkeley Lab)...
Cadmium-Free Tetrapod QDs Developed
CARSON CITY, Nev., Feb. 19, 2013 — Quantum Materials Corp. (QMC) has developed a new class of cadmium-free, non-heavy metal tetrapod quantum dots (NHM-TPQDs) to address global concerns regarding nanoparticle biocompatibility and sustainability.
Tiny probes dramatically boost Raman signals
ST. LOUIS – Novel gold nanoparticles can goose the signal from Raman reporters, or molecules whose jiggling atoms respond to a probe laser by scattering light at characteristic wavelengths. The discovery could lead to better-targeted drug delivery and deeper...
Microactuator Flexes Under Laser Light
BERKELEY, Calif., Dec. 17, 2012 — A microscale actuator that flexes like a tiny beckoning finger under a burst of laser light may point toward practical applications in artificial muscles, microfluidics and drug delivery.
Implantable Silk Micromirrors Enhance Imaging
MEDFORD/SOMERVILLE, Mass., Nov. 30, 2012 — Silk-based implantable optics that significantly enhance tissue imaging can simultaneously enable photothermal therapy, monitor drug delivery and administer drugs.
Tiny Probes Dramatically Boost Raman Signals
ST. LOUIS, Nov. 26, 2012 — Novel gold nanoparticles can goose the signal from Raman reporters, or molecules whose jiggling atoms respond to a probe laser by scattering light at characteristic wavelengths. The discovery could lead to better-targeted drug delivery and deeper...
Laser ‘Needle’ Could Take the Ouch Out of Shots
SEOUL, South Korea, Sept. 14, 2012 — Children (and even adults) who dread facing needles at the doctor’s office can find hope in a new laser-based system that shoots microscopic jets of drugs into the skin. To test the effectiveness of the drug delivery system, a special gel is...
Nanoparticle-Laser Method Targets Chemo Drugs
HOUSTON, April 10, 2012 — A potential treatment method for drug-resistant cancer uses gold nanoparticles to convert laser energy into “plasmonic nanobubbles,” which allow chemotherapy drugs to enter single cells. Delivering chemotherapy with nanobubbles is 30 times more...
Nanophotonic Endoscope Gently Probes Single Cells
BERKELEY, Calif., Dec. 21, 2011 — A newly developed nanophotonic endoscope can take high-resolution images of the inside of a single living cell and deliver therapeutic drugs and other cargo without injuring or damaging the cell. Fluorescence confocal image of a single living...
Label-Free Bioimaging Tool Tracks Nanotubes
WEST LAFAYETTE, Ind., Dec. 12, 2011 — A new imaging tool tracks carbon nanotubes inside living cells and throughout the bloodstream, which could hone the particles’ usefulness in biomedical research and clinical medicine. Carbon nanotubes have potential applications in drug...
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April 2024
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