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fluorescence correlation spectroscopy News
Signal Enhancement Enables Study of Label-Free Proteins
MARSEILLE, France, Jan. 26, 2023 — Researchers at Institut Fresnel have developed a technique to detect the ultraviolet-autofluorescence signal in single proteins, opening the way for the label-free study of thousands of proteins whose natural fluorescence cannot be detected using existing technology. Though proteins are fluorescent in the UV because they contain tryptophan amino acids, most proteins have only one to five tryptophan — which is too few to provide a strong UV signal at the level required for label-free
Approach Uses Bayesian Analysis to Speed Spectroscopy Results
PHOENIX, Aug. 19, 2019 — Scientists from Arizona State University are leveraging the tools of data science to study molecular activity more quickly than is possible through traditional fluorescence correlation spectroscopy (FCS). While FCS provides estimates of dynamical...
Imaging of Nanoscale Pores Aids Drug Discovery
HOUSTON, Sept. 9, 2015 — Drug discovery efforts may get a boost from a new imaging technique based on superresolution microscopy and fluorescence correlation spectroscopy. Called fcsSOFI — for fluorescence correlation spectroscopy superresolution optical fluctuation...
Fluorescence Microscopy Given New Power
URBANA, Ill., Nov. 5, 2012 — A new method that studies the critical process of cell transport dynamics at multiple spatial and temporal scales has revealed properties of diffusive and directed motion transport in living cells.
Photonics West YIA Winners
SAN DIEGO, Calif., Feb. 25, 2009 – SPIE has announced the winners of the Young Investigator Award (YIA) from Photonics West 2009 in San Diego, Calif. As part of this year’s Photonics West, SPIE organized a special symposium called the “Single Molecule Spectroscopy and Imaging”...
Relationship of Temperature Rise to Incident Laser Power in Optical Traps
Apr 1, 2007 — Optical trapping often is used to evaluate nanometer-size systems by introducing up to hundreds of milliwatts of laser power into the focus. The resulting power intensity can raise local temperatures and induce unwanted physical, chemical or...
Making Fluorescence Correlation Spectroscopy Flexible
Sep 1, 2006 — Fluorescence correlation spectroscopy helps to shed light on the behavior of molecules in aqueous solutions by measuring fluctuations in fluorescence intensity. Typically, data is collected from a single, fixed-focus position within the sample....
(7 results found)
May 2024
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