Antibody-based Probe Developed for Live-Cell Imaging in Vivo
FORT COLLINS, Colo., July 5, 2019 — To expand the toolbox of imaging in living cells, researchers from Colorado State University and the Tokyo Institute of Technology have developed a genetically encoded, antibody-based probe that works with specificity in vivo. In this methodology, probes built from antibodies are genetically fused with mature fluorophores. When expressed or loaded into cells, the probes bind and light up epitopes within proteins of interest as soon as the epitopes are accessible. The probe, called the human