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two-photon microscopy News
Light-Beads Microscopy Reveals New Information About Brain Activity
NEW YORK, March 14, 2024 — Mammalian brains are known to be comprised of densely interconnected neurons, but a remaining mystery in neuroscience is how tools which capture relatively few components of brain activity have enabled scientists to predict behavior in mice. To better capture and understand neural activity in mice, professor Alipasha Vaziri and his team at The Rockefeller University used large-scale recordings and light-beads microscopy (LBM), a volumetric, two-photon imaging technique developed by the
High-Speed Two-Photon Microscopy Captures Rapid Bio Processes In Vivo
SUZHOU, China, May 15, 2023 — Two-photon microscopy (TPM) enables deep tissue imaging of complex biological processes at high resolution. However, the ability to visualize some biological processes, such as neural activity at the sub-millisecond scale, requires high-speed...
Technique Enables In Vivo Vascular Imaging at Single-Cell Resolution
HONG KONG, Sept. 22, 2022 — A two-photon fluorescence imaging method developed by researchers at the University of Hong Kong and the University of California, Berkeley was able to image the flow of individual blood cells at 1000 2D frames and 1,000,000 line-scans per second in...
Multiphoton Microscopy Technique Advances into Clinical Settings
IRVINE, Calif., Dec. 16, 2021 — An instrument developed and introduced by researchers at the University of California, Irvine (UC Irvine) demonstrated the potential to expedite the adaptation of conventional multiphoton microscopy (MPM) for use in clinical settings. The compact,...
Reflection Matrix Microscopy Could Expedite Neuroscience Research
DAEJON, South Korea, Dec. 4, 2020 — A South Korean research team has developed an optical microscope capable of maintaining spatial resolution and acquiring a microscopic “map” of neural network activity in brain tissue as it images through the width of an intact mouse...
AO Two-Photon Endomicroscopy Achieves Synaptic Resolution
HONG KONG, Oct. 12, 2020 — Scientists from the Hong Kong University of Science and Technology (HKUST) developed a technology for in vivo imaging of deep brain structures at synaptic resolution. The technology, “adaptive optics two-photon endomicroscopy,” enables...
Intravital Imaging Provides Insight into Liver Disease Progression
DAEJEON, South Korea, Sept. 3, 2020 — The high-resolution, 3D-viewing capabilities provided by a new microscopy method from the Korea Advanced Institute of Science and Technology (KAIST) could lead to insights into nonalcoholic fatty liver disease (NAFLD), a condition in which too much...
2-Photon Microscopy Shows Learning Involves Various Areas of Brain
BALTIMORE, Jan. 8, 2020 — To explore how learning and memory-building take place in the brain, scientists at Johns Hopkins University School of Medicine used a laser-assisted imaging tool to monitor and measure levels of AMPAR molecules, which help send messages between...
Compressive Sensing Techniques Speed 2-Photon Microscopy
HONG KONG, Sept. 16, 2019 — To enhance the imaging speed of two-photon microscopy without compromising resolution, researchers from The Chinese University of Hong Kong combined compressive imaging techniques with a multifocus laser illumination method that uses a digital...
Two-Photon Microscope Captures Brain Activity at Record Speed
ASHBURN, Va., Aug. 9, 2019 — A new two-photon microscope from scientists at Howard Hughes Medical Institute’s Janelia Research Campus records footage of brain activity 15 times faster than once believed possible, the team said, revealing voltage changes and...
Technique ‘Pre-Corrects’ Microscope Illumination
REHOVOT, Israel, Sept. 11, 2014 — A new adaptive optics technique focuses laser light through dense tissues without the need for an invasive guide star. The technique can resolve a point less than a micron across. It was developed by a team led by the Weizmann Institute of Science....
Two-Photon Microscopy Reveals Skin-Allergen Connection
GOTHENBURG, Sweden, Dec. 30, 2011 — Two-photon microscopy has shown that the skin absorbs various substances differently, depending on what they are mixed with. These differences may determine whether a substance causes contact allergy. “We have also been able to identify...
Sheets of Light Image Live Cells
ASHBURN, Va., March 7, 2011 — Using an exquisitely thin sheet of light, a newly developed microscope reveals the 3-D shapes of cellular landmarks in unprecedented detail. The technique images live cells at high speed so that researchers can create dazzling movies that make...
Optics Trends: Optical tech sparkled in 2009
Jan 4, 2010 — In a year that has seen the biggest recession in decades hit most market segments, you might expect a look back at the optics industry in 2009 to be all gloom and doom. But there a...
Adaptive Optics in Biological Imaging with Two-Photon Microscopy
Dec 1, 2009 — Cutting-edge biological microscopy has enabled researchers to explore tissue at the subcellular level in vivo. Having the ability to observe physiological processes in vivo has led to breakthroughs in our understanding of cancer, eye disease and...
Chirped Fiber Improves Pulse
BERLIN, Oct. 29, 2008 -- By introducing a radial chirp into a photonic crystal, researchers in Germany and Russia have developed a novel optical fiber that can transmit ultrashort light pulses with very little distortion over extended distances. The fiber could prove useful...
Photonics Used to Study Cerebral Blood Flow
Feb 1, 2006 — A pair of independent studies using photonics to investigate the flow of blood in the brain may enable a better understanding of neurological disorders such as Alzheimer’s disease and strokes. In the work described in the Dec. 25 online edition of...
(17 results found)
May 2024
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