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Deposition Sciences Inc. - Difficult Coatings - LB - 8/23

Chemical coating keeps quantum dots in the cytosol

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David L. Shenkenberg

In many ways, quantum dots are superior to typical fluorophores, but they cannot easily enter cells without chemical modification to their surface. Even if they enter cells, they may get stuck within cellular compartments. To address these issues, researchers at Emory University in Atlanta developed a chemical coating that enables quantum dots to enter cells and stay in the cytosol. In their experiments, they used conventional CdSe quantum dots coated with CdS and covered with a ZnS shell. They first coated the quantum dots with polyethylenimine, a polymer that enables the quantum dots to...Read full article

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    Published: May 2007
    Glossary
    quantum dots
    A quantum dot is a nanoscale semiconductor structure, typically composed of materials like cadmium selenide or indium arsenide, that exhibits unique quantum mechanical properties. These properties arise from the confinement of electrons within the dot, leading to discrete energy levels, or "quantization" of energy, similar to the behavior of individual atoms or molecules. Quantum dots have a size on the order of a few nanometers and can emit or absorb photons (light) with precise wavelengths,...
    Basic ScienceBiophotonicschemical coatiangCoatingsfluorophoresMicroscopyquantum dotsResearch & Technology

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