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SMS Reveals Hidden Behaviors

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Single-molecule spectroscopy (SMS) is gaining traction in a wide range of fields, from DNA sequencing to understanding how cells, drugs, genes or proteins interact.

MARIE FREEBODY, CONTRIBUTING EDITOR, [email protected]

It was 28 years ago that the first optical experiments to detect a single molecule took place in the Moerner Laboratory at IBM Research, with relatively esoteric, low-temperature, high-resolution spectral measurements. Since then, room-temperature demonstrations and research efforts of many scientists all over the world have led to a true explosion of the method. New applications and different ways to characterize individual molecules appear almost on a weekly basis. “Single-molecule optical spectroscopy now has broad applications, ranging from basic science to shining light on the...Read full article

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