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BioPhotonics - Sep/Oct 2025


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Features
Raman and Laser-Induced Breakdown Spectroscopy Augment Chemical Analysis Raman and Laser-Induced Breakdown Spectroscopy Augment Chemical Analysis Raman spectroscopy and laser-induced breakdown spectroscopy (LIBS) are two laser-based optical methods that provide complementary insights into the chemical composition of materials. Raman...
Smartphone-Based NIRS Imaging Classifies Wounds Smartphone-Based NIRS Imaging Classifies Wounds Diabetes mellitus affects >32.2 million people in the U.S. and an additional 12.5% of the U.S. population is prediabetic1. One in three people with diabetes is affected by diabetic foot ulcers...
Foveation and Spectral Imaging: Nature-Inspired Data Reduction for Efficient Devices Foveation and Spectral Imaging: Nature-Inspired Data Reduction for Efficient Devices Hyperspectral imaging (HSI) holds great promise for medicine as it matures into a practical technology. The fusion of imaging methods that spatially resolve light energy passing through an opening...
Fluorescence Microscopy and Microfluidics Intersect for Biological Discovery Fluorescence Microscopy and Microfluidics Intersect for Biological Discovery Microfluidics has transformed from a niche technology into a fundamental tool for biological experimentation during the last decade. When coupled with wide-field fluorescence microscopy, it enables...
Editorial
The gravity of cellular changes The gravity of cellular changes Microfluidics and fluorescence microscopy have long been integral to diagnostics and the life sciences. Recently, a group of researchers advanced this union into space — at least in principle. This collaboration, involving Newcastle University in England, Stanford University in the U.S., and the European Space Agency (ESA), aimed to investigate how microgravity affects cellular processes,...
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SCIX Plots the Journey from Analysis to Discovery SCIX Plots the Journey from Analysis to Discovery From a keynote talk focusing on the pursuit of unidentified anomalous phenomena (UAPs) to individual academic sessions delving into the use of spectroscopy to uncover evasive clues in infectious diseases, the theme of SCIX 2025 will revolve around unlocking some of the mysteries of science in biomedicine and beyond. The conference, hosted by the Federation of Analytical Chemistry and Spectroscopy...
BioScan
ZEISS Acquires Longstanding Collaborator Pi Imaging ZEISS, via Carl Zeiss Microscopy GmbH, acquired all equity shares of longtime partner Pi Imaging Technology SA, based in Lausanne, Switzerland. Pi Imaging Technology now operates as Pi Imaging...
Waters, BD’s Biosciences & Diagnostic Solutions to Merge Waters Corporation, a provider of analytical instruments and software for medical, food, and environmental markets, and BD (Becton, Dickinson and Company) have entered into a definitive agreement to...
Suspended Cells Imaged in 3D Using Optical Tweezers Suspended Cells Imaged in 3D Using Optical Tweezers Optical sectioning (OS) enables 3D bioimaging, but it requires non-optical techniques, like sample adhesion and mechanical scanning, to hold and manipulate cells. In situ living cells may lack...
Trinity College Hosts Ireland’s First BioBrillouin Microscope Trinity College Hosts Ireland’s First BioBrillouin Microscope Trinity College is now home to Ireland’s first and only BioBrillouin microscope. The device is expected to enable strides in the fields of inflammation, cancer, developmental biology, and...
Alcon Acquires LumiThera, Adds Noninvasive Solution Alcon, a global developer of eye care devices including products for ophthalmic surgery and contact lens solutions, will acquire LumiThera, an ophthalmic medical device company. The deal includes...
Quantum Sensor Uses its Own Light to Detect Biomolecules Quantum Sensor Uses its Own Light to Detect Biomolecules The development of a compact, self-illuminating plasmonic sensor could make high-performing optical biosensors more accessible for rapid diagnostics and environmental monitoring and in point-of-care...
Terahertz Light Probes Tissue Changes for Diagnosis Terahertz Light Probes Tissue Changes for Diagnosis Changes in tissue structure, such as to the boundaries of cancerous tumors, occur in many disease processes. Terahertz (THz) waves demonstrate the potential to detect these changes. The ability to...
Doublet Design Overcomes a Metalens Microscopy Bottleneck Doublet Design Overcomes a Metalens Microscopy Bottleneck A research team from Nanjing University has developed a solution that improves metalens performance in and for microscopy applications. The researchers’ metalens-based microscope achieves both...
Photons Measured Through Head Show Imaging Potential Photons Measured Through Head Show Imaging Potential With the appropriate optical setup, it is possible to measure photons as they travel diametrically across the inside of the adult human head. This discovery, made by scientists at the University of...
Light-Based Bacteria Control May Quell Antibiotic Resistance Light-Based Bacteria Control May Quell Antibiotic Resistance Bacterial resistance to antibiotics is a growing challenge for the health care and environmental sectors. Bacterial persistence is usually the first step leading to resistance, which involves a...
Quanta Sensors Boost Bioluminescence for Microscopy Quanta Sensors Boost Bioluminescence for Microscopy A microscope built with quanta image sensor (QIS) technology will allow researchers to visualize bioluminescence signals in living cells in detail and over long durations. Researchers at Helmholtz...
Hamamatsu, Vizgen Partner on Biomarker Detection Hamamatsu has established a partnership with Vizgen, Inc., a life sciences company advancing spatial multi-omics. The collaboration integrates Hamamatsu’s MoxiePlex multiplex immunofluorescence...
3 Questions
3 Questions with Zhen Tian 3 Questions with Zhen Tian BioPhotonics spoke with Zhen Tian, a professor in the Department of Opto-Electronics Science Technology at Tianjin University. Tian was the corresponding author on a paper that described the use of terahertz optics to monitor blood sodium, as described in Optica. The technique shows the potential to measure blood sodium levels in real time without the need for sampling and time-consuming...
BioOpinion
Changing the Quantum Sensing Landscape Changing the Quantum Sensing Landscape Advancements in quantum information science promise exciting new applications, including for biomagnetism and biomedical research. While quantum computing garners the most attention and funding from governmental agencies, industry, and venture capital, optically probed quantum sensors are arguably the most mature quantum technology, including in the life sciences. Industry and startup companies...
Postscripts
Three blind mice that can now see! Three blind mice that can now see! Blind mice were granted the ability to see in a recent experiment that could guide medical research toward greatly improved vision in blind human beings. In nature, animals such as snakes assess their surroundings by sensing both infrared radiation and the visible light spectrum. That’s clever on the reptiles’ part, but regrettably, humans do not have this superpower, because their...
Products
Intraoral Camera Intraoral Camera DensiCAM from e-con Systems is a full HD intraoral camera for dental imaging. The camera's <2% distortion confirms minimal geometric distortion, for accurate clinical observation and documentation. With a depth of field ranging from 5 - 80 mm, DensiCAM captures clear images from anterior teeth to molars in a single frame. Its wide 90° field of view covers quadrant and individual tooth...
e-con Systems Inc.
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Photoacoustic Imaging Platform Photoacoustic Imaging Platform Vevo F2 LAZR-X20 from FUJIFILM VisualSonics is an ultrahigh- to low-frequency photoacoustic ultrasound system designed for applications of oncology, cardiovascular, neurobiology, and molecular...
FujiFilm VisualSonics Inc.
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Hybrid Surgical Microscope Hybrid Surgical Microscope ARveo 8x from Leica Microscopes is a hybrid surgical microscope for neurosurgery, spine, and plastic reconstructive procedures. ARveo 8x has a working distance of 600 mm to maneuver large...
Leica Microsystems GmbH
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Fiber Laser Fiber Laser ACE FL series fiber lasers from Coherent are thulium fiber lasers designed for therapeutic medical applications, specifically lithotripsy and benign prostatic hyperplasia treatment. The thulium fiber...
Coherent Corp.
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Femtosecond Laser Series Femtosecond Laser Series The FS Air Cooled Series from Photonics Industries is a series of air-cooled, all-fiber-based, fully solid-state femtosecond laser platforms, with up to 8 W average power and pulse energies up to 8...
Photonics Industries International Inc.
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Flow Cytometer Flow Cytometer The Cytek Aurora Evo system from Cytek Biosciences is a full-spectrum flow cytometer designed for cell biology, immunology, oncology, and targeted therapeutic methodologies. Using Cytek’s Full...
Cytek Biosciences Inc.
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Raman Spectrometer Raman Spectrometer Lightnovo’s research-grade Raman spectrometer is designed for low-frequency Raman and high-sensitivity measurements. The spectrometer has an ultrastable laser output, a spectral range from 70...
Lightnovo ApS
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sCMOS Camera sCMOS Camera The ORCA-Halo, C17440-20U from Hamamatsu Photonics is a scientific CMOS (sCMOS) camera for applications such as advanced and light sheet microscopy. The camera has a back-illuminated sensor with a...
Hamamatsu Corporation
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Spinning Disk Confocal Microscopes Spinning Disk Confocal Microscopes The IXplore™ SpinXL (shown) and the IXplore™ IX85 SpinSR from Evident are spinning disk confocal microscopes for imaging rapid cellular dynamics. IXplore Spin XL has a 26.5-mm field...
Evident
LED Product Line LED Product Line The CFT-50X Series from Luminus Devices is for applications including medical endoscopy, biophotonics, fluorescence microscopy, and industrial machine vision. The LED series offers 10 distinct SKUs...
Luminus Devices Inc.
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Nanopositioning Stages Nanopositioning Stages The B-421 BIX series from PI features nanopositioning stages for high-precision positioning systems. BIX series products use two miniature piezo stacks, and the bi-phase inertia drive technology...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Cyan Laser Diode Cyan Laser Diode The PLT5 488HB_EP from ams OSRAM is a cyan laser diode designed for life sciences applications including DNA sequencing and flow cytometry. The laser diode emits at 488 nm, with a wavelength control...
ams OSRAM
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LWIR Protective Windows LWIR Protective Windows The SiLWIR™ (Silicon LWIR) series from Midwest Optical Systems features diamond-like carbon- and double-sided antireflective-coated silicon LWIR protective windows for thermal imaging. The...
Midwest Optical Systems Inc. (MidOpt)
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