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BioPhotonics
April 2007
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FEATURES
A Fluorescent Phantom for Small-Animal Imaging
Small animals represent vital model systems for the study of organism development and human disease. They are increasingly recognized as powerful discovery tools in genetic, proteomic and cancer research. For example, animal studies have vast utility in studying efficacy and toxicity of novel cancer therapeutics. Until recently, the significant potential of animal studies was untapped because...
Controlled Light Exposure Microscopy for Confocal Imaging
Fluorescence imaging of live cells and tissues is a powerful technique that is increasingly finding new applications in the biological sciences.1 However, photobleaching and phototoxicity can present...
Taking It to the Streets with SPR
Surface plasmon resonance (SPR) — a label-free technique for measuring biomolecular interactions in real time — benefits a wide variety of applications, from basic science to drug discovery. The...
AS WE GO TO PRESS
Imaging agent detects amyloid-ß
Researchers have now confirmed that PET imaging with the contrast agent Pittsburgh Compound B (PiB) can detect amyloid-ß in the brains of dementia patients. Early work with mouse models of...
Fluorescent assay can find potential anti-HIV drugs
Current antiretroviral drugs can slow the onset of AIDS, but no cure exists for the disease, so new drugs must be developed. Researchers at the University of California, San Diego, in La Jolla have...
An alphabet too small to read without a microscope
At the University of California, Los Angeles, researchers have developed a method for producing colloidal dispersions of letter-shaped microscopic particles. The structures may have application in...
Fighting malaria with resistant mosquitoes
Forty-one percent of the world’s population lives where malaria is transmitted, according to the Centers for Disease Control and Prevention in Atlanta. One strategy that scientists are exploring for...
BREAKTHROUGHMEDIA
Optics resource
Edmund Optics has released the “2007 Master Source Book,” a resource for optical system designers that is available in both print and pdf. Along with illustrations, the document specifies the company’s products, including nearly 110 items that are not listed in the standard catalog. It presents volume pricing figures to facilitate the evaluation of financial as well as technical trade-offs in...
Photonic components
Melles Griot has launched its “New Products Winter 2007” brochure. Complementing the comprehensive “Catalog X,” the downloadable publication highlights more than 20 photonic product families,...
Optical filters
The 47-page, full-color “2007 Catalog” from Semrock Inc. details optical filters for biotechnology and analytical instrumentation, including BrightLine fluorescence filters, such as the single- and...
Photonics textbook
The full-color Fundamentals of Photonics, Second Edition, provides new material on photonic crystal optics, including multilayer and periodic media, waveguides, holey fiber and resonators; ultrafast...
Labeling, detection
“BioProbes 52,” the March issue of a newsletter published by Molecular Probes Inc., includes articles on emerging technologies, such as Click-iT glycoprotein profiling reagents, a Premo cameleon...
Microscopy supplies
The full-color, 784-page “Catalog XV: 2007-2010” from Electron Microscopy Sciences (EMS) specifies its line of microscopy and histology supplies, accessories and chemicals for use in areas such as...
Antibodies research
A global supplier of monoclonal and polyclonal antibodies and custom antibody production services, ABR—Affinity BioReagents has released its “Antibodies 2007” catalog. A section of the 440-page...
Protein interaction
The “Biacore Systems and Consumables 2007” catalog from Biacore AB, GE Healthcare, describes the company’s systems for label-free protein interaction analysis in applications ranging from research to...
Sample preparation
Available from Millipore Corp., the “Analytical Sample Preparation” catalog highlights the company’s filtration and purification products for removing contaminants prior to instrument analysis. Among...
POST SCRIPTS
Reducing pain in phantom limbs
Many individuals who have undergone amputation of an arm or leg experience pain in the missing limb — a phenomenon referred to as phantom limb pain. The sensations can seem as real as aches and pains in the rest of their body. To help people deal with this condition, the mirror box was developed more than 10 years ago. The device enables users to interpret motion of their functioning limb as...
PRODUCTS
Spectrophotometer
The V-630Bio offered by Jasco Inc. consists of an intelligent remote module (iRM) and a micro cell holder designed for protein/nucleic acid measurement, DNA melting analysis, and kinetics measurement...
JASCO Inc.
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Measuring cell
The TrayCell fiber optic microliter cell from Hellma GmbH & Co. KG is designed for applications such as protein and nucleic acid analysis, determining the incorporation frequency of fluorescent...
Hellma GmbH & Co. KG
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Research system
Illumina Inc. has launched the BeadXpress system for research and clinical development applications. The system uses the company’s VeraCode digital microbead technology to provide high-quality data,...
Illumina Inc.
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Fiber lasers
The VFL-P series compact visible fiber lasers offered by MPB Communications Inc. have been expanded with the 592-nm orange fiber laser. The CW lasers are offered in a modular package and produce...
MPB Communications Inc.
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Molecular imaging
Bruker Daltonics Inc. has added new features to its Maldi Molecular Imager system for biomarker detection, tissue classification and pathology research, and for imaging the distributions of drugs and...
Bruker Daltonics Inc.
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Four-megapixel cameras
The TM-4200 progressive scan cameras from JAI Inc. feature 4-megapixel resolution (2048 × 2048) at 15 fps in dual-tap mode. Software-selectable single-tap mode is available at 8 fps. The devices...
JAI Inc.
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Fast amplifier
The Legend Elite from Coherent Inc. is a one-box regenerative ultrafast amplifier suitable for investigations into nonlinear optics and for studying molecular dynamics, photochemistry, photoelectron...
Coherent Inc.
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Nanopositioning stage
PI (Physik Instrumente) LP has unveiled the M-511.HD hybrid nanopositioning translation stage, which can be used in nanometrology, microscopy, laser technology and interferometry. The hybrid system...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Microdissection system
The ArcturusXT microdissection system from Molecular Devices Corp. combines IR laser capture microdissection and UV laser cutting in one instrument. Built upon the Nikon TE2000U inverted microscope,...
Molecular Devices LLC
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Scientific software
Comsol Inc. has released version 3.3a of its Multiphysics simulation environment software. The upgraded package includes a library with 2500 materials for quick and accurate model setup. It offers...
COMSOL Inc.
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Confocal Raman system
The MonoVista confocal Raman microscope systems from Princeton Instruments/Acton offer both macro- and confocal microanalysis capabilities in a single system. Integration with Olympus upright and...
Teledyne Princeton Instruments
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TEM00 lasers
Photonics Industries International Inc. has unveiled its PA series high-power TEM00 lasers, which deliver up to 150 W in the IR at 1064 nm; up to 100 W in the green at 532 nm; up to 40 W in the UV at...
Photonics Industries International Inc.
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UV cameras
CAM1M30 back-illuminated digital UV cameras from Sarnoff Imaging Systems can be used for microscopy, spectroscopy and forensics. The CCD cameras provide a resolution of 1000 × 1000 pixels, a rate of...
SRI International, Integrated Systems & Solutions
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IR nerve stimulator
An IR nerve stimulator designed for medical research and scientific applications has been unveiled by Aculight Corp. The Capella R-1850 penetrates tissue to a depth of 300 to 600 μm and has a...
Lockheed Martin Laser and Sensor Systems
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Drug analysis
The TPI imaga 2000 terahertz imaging system from TeraView Ltd. can provide complete 3-D imaging of intact tablet cores and coatings. The machine uses pulsed emission in the terahertz wavelength...
TeraView Ltd.
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Sapphire lenses
Hemispherical lenses made from sapphire are available from Edmund Optics Inc. The hard, tough sapphire material makes them suitable for use in severe environments, allowing them to withstand exposure...
Edmund Optics Inc.
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Optical fibers
OFS Specialty Photonics has unveiled four optical fibers double-clad with erbium and ytterbium for high-power amplifiers and lasers. Single-mode fibers with a 6-μm core and medium-mode fibers...
OFS
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Digital microscopy
Version 4.6 of the AxioVision software for digital microscopy has been released by Carl Zeiss MicroImaging GmbH. Suitable for biomedicine and materials applications, the software features new...
Carl Zeiss Spectroscopy GmbH
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NIR spectrometer
A compact near-infrared spectrometer with scanning grating technology has been unveiled by HiperScan GmbH. The technology allows the entire spectrum to pass a single highly sensitive InGaAs detector...
HiperScan GmbH
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Spectroscopy system
Ocean Optics Inc. has released the LIBS2500, a laser-induced breakdown spectroscopy system. It permits instant qualitative measurements of elements in solids, solutions and gases for use in materials...
Ocean Insight
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Fiber-coupled module
Dilas Diode Laser Inc. has added the 1470-nm single-wavelength, fiber-coupled module to its family of conduction-cooled modules. Suitable for medical applications, the module has power levels of 12,...
DILAS Diode Laser Inc.
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Low-profile stage
Steinmeyer Inc. has unveiled the PMT160-DC single-axis positioning stage with an overall height of only 40 mm. The total travel ranges from 50 to 300 mm in each direction, and the stage can handle...
Steinmeyer Inc.
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Laser system
Continuum, a subsidiary of Excel Technology Inc., has released the Powerlite Plus Two Joule Option for researchers seeking higher levels of green energy for pumping Ti:sapphire lasers. The system...
Amplitude Laser Inc.
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Rod lenses
Grintech GmbH has expanded its line of rod lenses with six additions designed for fiber coupling and beam shaping of laser diodes. The lenses all have diameters of 2 mm and focal lengths ranging from...
Grintech GmbH
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Line sensor
Hamamatsu Corp. is offering the C10413 radiation line sensor. The device is an x-ray and gamma radiation scanner that produces data for acquiring energy-differentiated color images based on as many...
Hamamatsu Corporation
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Video camera
Photron Inc. has released a high-speed megapixel video camera. The Fastcam SA-1 operates at 5000 fps with full megapixel resolution. CMOS sensor technology allows slow-motion video imaging with...
Photron USA Inc.
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LATEST PRODUCTS
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HORIBA Scientific
Cooled sCMOS Cameras
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Motion Controller
FAULHABER MICROMO
Microscopy Software
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