Fluorogenic Probes Track Transmission of Infectious Disease and Track Gene Expression
Biofilm disassembly and dispersal play a key role in disease spread, but studying these processes with microscopy and related imaging techniques is challenging. The fluorescent proteins traditionally used to label cells lose functionality in the oxygen-deprived biofilm environment, inhibiting close observation of the biofilm dispersal process. To resolve this issue, a team at Carnegie Mellon University labeled cells with oxygen-independent fluorogen-activating proteins and cognate far-red dyes.
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Hamamatsu, Vizgen, Collaborate for Enhanced Biomarker Detection Capabilities
Hamamatsu has established a partnership with Vizgen, Inc, a life sciences company advancing spatial multi-omics. The collaboration integrates Hamamatsu’s MoxiePlex multiplex immunofluorescence imaging system with Vizgen’s pathology-grade reagent and assay portfolio to bring multiplexed biomarker detection into new translational and clinical research applications. According to the companies, the partnership aims to offer a joint solution to eliminate common barriers in multiplex assay development — streamlining validation, simplifying workflow integration, and enabling researchers to focus on acquiring high-fidelity biological insights.
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Imaging Method Allows High-Speed 4D Videos of Moving Organisms
Biomedical researchers at Duke University have developed a computational imaging system that borrows techniques from astronomy to reconstruct 4D videos of freely moving small model organisms, like zebrafish and fruit fly larvae. By using a concave mirror and an array of sensors, researchers were able to rapidly capture the unrestrained movements of animals from dozens of synchronized viewpoints.
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Features
Chip-Based Imaging, Mid-IR Spectroscopy, OCT and Diagnostics, and Liquid Lenses
Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazine BioPhotonics. Please submit an informal 100-word abstract to Senior Editor Doug Farmer at Doug.Farmer@Photonics.com, or use our online submission form www.photonics.com/submitfeature.aspx.
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