Monthly newsletter focusing on how light-based technologies are being used in the life sciences.
Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy, lighting and more. Manage your Photonics Media membership at BioPhotonics.com/subscribe.
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Multiphoton Microscopy Provides a Deeper View of the Aging Brain
Because deep-brain structures are key to how the nervous system communicates and maintains healthy function, understanding them is crucial for studying neurovascular dynamics, age-related changes, and neurodegenerative diseases. Multiphoton microscopy has become a widely used tool for imaging the mouse brain in neuroscience, particularly for visualizing neurons and vasculature. Its advantage compared with other technologies lies in its ability to deliver live-cell images and reveal active cellular processes as they occur, rather than only providing static details.
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Fiber Optics Clarifies the View of Neural Activity
Optical fiber was once relegated to simple light delivery and collection in medical instruments, often for exploratory procedures. Today, this fiber winds its way into all manner of instrumentation in the laboratory and clinic, capturing health data from complex — and often hard-to-reach — biological systems. The data then reveals information ranging from temperature and blood flow to cellular signaling for diagnostics.
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Multifocus Microscope Pushes Limits of 3D Imaging
A high-speed 3D imaging microscope developed by researchers at the University of California, Santa Cruz can capture detailed cell dynamics of an entire small whole organism at once. The ability to image 3D changes in real time over a large field of view could lead to new insights in developmental biology and neuroscience. “Traditional microscopes are constrained by how quickly they can refocus or scan through different depths, which makes it difficult to capture fast, 3D biological processes without distortion or missing information.
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