Advancing Raman Spectroscopy by Using Bioresponsive Optical Nanomaterials
Wed, May 7, 2025 1:00 PM - 2:00 PM EDT
Raman spectroscopy provides label-free molecular characterization by detecting chemical bond vibrations, enabling direct visualization of molecular responses in living cells and tissues. Despite significant advancements, the clinical translation of Raman spectroscopy has been hindered by two key challenges: limited detection sensitivity and insufficient specificity. For instance, it has not found use in imaging enzyme activity, a significant aspect of biomedical research.Leveraging nature-inspired self-assembly strategies, intracellular bioorthogonal enzyme-responsive nanoprobes (nanoSABER) have been developed. Engineered from enzyme-responsive peptides, these nanoprobes assemble into supramolecular structures with distinct Raman-active vibrational signatures upon interaction with targeted enzymes. Incorporating vibrational tags such as alkyne (C=C) and nitrile (C=N) groups within the cell-silent Raman window (1800 to 2600 cm-¹), nanoSABER specifically images enzyme activity with minimal interference from endogenous cellular signals.
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How to Select a Precision Automation System for High-Volume Optical Alignment
Thu, May 8, 2025 1:00 PM - 2:00 PM EDT
Achieving submicron positioning in optical alignment applications is critical in the production of optical components and systems used in the consumer electronics, automotive, and defense industries. Precision motion control solutions, including direct-drive stages and hexapods, play a key role in optimizing active alignment processes and ensuring quality through repeatable results. However, selecting the right positioning system is not always easy. This webinar will provide a technical overview of six-degrees-of-freedom (6-DOF) positioning architectures and their effect on alignment quality. It will examine the role of active alignment algorithms and control systems on alignment quality and repeatability. Additionally, it will examine real-world case studies that highlight trade-offs between different motion control technologies and demonstrate strategies for maximizing throughput while maintaining alignment integrity. Designed for optical engineers, automation engineers, and manufacturing engineers, this webinar will equip attendees with the knowledge required to make informed decisions when specifying motion control solutions for optical alignment applications. Presented by Aerotech Inc.
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Laser-Based Additive Manufacturing Steps into the Blue — With Lukas Hoppe
Additive manufacturing garners considerable attention — but the methods and underlying technology often take a back seat to the remarkable designs and properties of finished works. Lukas Hoppe, R&D director at Meltio, offers insights into the current laser-based additive manufacturing ecosystem. Hoppe discusses Meltio’s blue laser innovations as well as wire-laser metal 3D printing methodology.
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