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multiphoton microscopy News
Microprism-Mediated Calcium Imaging Reveals Neural Dynamics Over Time
SEATTLE, April 10, 2024 — An approach to deep brain imaging developed at the University of Washington uses microprisms to provide stable tracking of neuronal activity over a large field of view. According to the research team, the microprism technique is a significant improvement over existing imaging methods used to characterize neuronal ensemble dynamics within deep brain tissues. Organisms rely on their brains’ complex neural circuits to process information and perform functions that will help them find
Three-Photon Microscopy Reveals Immune Cell Behavior in Real Time
ITHACA, N.Y., Feb. 10, 2022 — A research group from Cornell University has used three-photon microscopy to image the full depth of the popliteal lymph node in a living mouse — reportedly for the first time. The researchers successfully observed the dynamic interactions of...
Multiphoton Microscopy Technique Advances into Clinical Settings
IRVINE, Calif., Dec. 16, 2021 — An instrument developed and introduced by researchers at the University of California, Irvine (UC Irvine) demonstrated the potential to expedite the adaptation of conventional multiphoton microscopy (MPM) for use in clinical settings. The compact,...
Multiphoton Microscopy Protocol Reveals Breast Cell Function, Behavior Inside Living Tissue
PARKVILLE, Australia, March 3, 2021 — A team from the Walter and Eliza Hall Institute of Medical Research in Australia has shown the ability to image tissue cells in the breast, without harming them, to observe their behavior at microscopic levels. The team used multiphoton microscopy,...
High-Speed Microscopy Tracks Millisecond Voltage Changes in Neurons of Awake Mice
BERKELEY, Calif., March 23, 2020 — University of California, Berkeley, researchers have built a microscope that can image the brain of an alert mouse 1000 times a second and record the passage of millisecond electrical pulses through neurons. The new imaging technique combines...
High-Speed 3D Inspection with Liquid Lenses
Sep 23, 2019 — The concept of liquid lenses, which involves controlling the shape of a liquid to alter the properties of a lens, is not new. The human eye uses this concept every day as it focuses on objects near and far. The ciliary body of the human eye contains...
Multiphoton Microscopy Reveals Lattice Network of Skin Fibers
KYOTO, Japan, Aug. 2, 2019 — Using multiphoton microscopy (MPM), researchers at Kyoto University showed that the collagen fibers in the skin are arranged in a mesh-like lattice and not in a clear geometric orientation as previously thought. They further found that the...
Muscle Weakness Measured with Multiphoton Imaging
ERLANGEN, Germany, Dec. 3, 2018 — Scientists at University of Erlangen-Nuremberg (FAU) have engineered an automated, high-precision biomechatronics system into a multiphoton microscope. The system allows isometric calcium ion (Ca2+)-graded force (or passive viscoelasticity...
Lasers: A Unique Microscopy Source
Nov 2, 2018 — The optical microscope dates back to the time of Galileo. For most of the past century, microscopy was widely regarded as a ubiquitous and extremely mature field. Today, the picture is very different. Optical microscopy is an incredibly dynamic...
Microscopy Add-On Enhances Neuronal Image Resolution Under Dim Conditions
TEL AVIV, Israel, Sept. 18, 2018 — A new add-on for laser-scanning microscopes, built from commercially available hardware and open-source software, could improve the quality of 2D and 3D imaging of neuronal activity in the living brain, even under photon-deprived imaging conditions....
Optics, Tunable Lasers to Move Multiphoton Microscopy Forward
Dec 20, 2016 — Of the numerous far-field imaging techniques, multiphoton microscopy has proved particularly valuable in many biological studies, providing multimodal images from deep within tissue, as well as label-free images of complex biological structures and...
Thorlabs Acquires Laser Line, Expands
May 1, 2012 — In Newton, N.J., Thorlabs Inc. has acquired the Octavius line of ultrafast lasers and ultrafast pulse characterization products from idesta Quantum Electronics (IQE). The transaction is expected to strengthen Thorlabs’ portfolio with lasers...
Thorlabs Acquires Ultrafast Laser Line
NEWTON, N.J., March 14, 2012 — The photonics tools manufacturer has acquired the Octavius line of ultrafast lasers and ultrafast pulse characterization products from idesta Quantum Electronics.
Multiphoton Endoscope May Equal Fewer Biopsies
ITHACA, N.Y., Nov. 3, 2011 — Taking multiphoton microscopy into a new dimension, a new imaging device under development that can be inserted safely into a patient’s body could minimize the need for unnecessary biopsies. Researchers at Cornell University are...
Hot Flies Produce Cool Results
ITHACA, N.Y., Sept. 25, 2006 -- Using multiphoton fluorescence microscopy, researchers have for the first time watched chromosomes change form to activate their genes to synthesize key proteins in fruit fly cells. The advance could be a significant step toward understanding the...
Imaging Method Records Nerve Cell Signals
Mar 5, 2004 — ITHACA, N.Y., March 5 -- Combining the bright laser light of multiphoton microscopy with specially developed dyes and a phenomenon called second-harmonic generation, biophysicists have made high-resolution images of millisecond-by-millisecond...
Quantum Dots Brighten Biological Images of Animals
May 30, 2003 — HAYWARD, Calif., May 30 -- Researchers have demonstrated a new approach to using quantum dots for biological studies of living animals. A new application of multiphoton microscopy makes tiny blood vessels beneath a mouse's skin appear so bright and...
(17 results found)
April 2024
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