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Imaging Webinars
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Harnessing Photons for Bond-Selective Imaging, Neuromodulation, and the Killing of Superbugs
Chemical microscopy that utilizes fingerprint vibrational spectroscopic signals opens a new window to visualizing the orchestra of molecules and biological structures inside living systems. Ji-Xin...
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Cutting-Edge 3D Raman Imaging in the Life Sciences
Raman imaging is a versatile, label-free, and nondestructive microscopy technique that can characterize many types of materials, including biological samples. It provides information about their...
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KEYNOTE: Specialized Laser Probes Capture Fluorescence Detail and Drive Diagnostics
Arrigoni discusses the various applications of lasers to biology and medicine, and categorizes them by the type of process involved and the most significant trends: Fluorescence (spectral) imaging by...
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Multiline Lasers Help Simplify Systems Based on Light-Sheet Microscopy for Clinical Applications
Fluorescence imaging using lasers is a key technique in both biomedical research and clinical applications. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore...
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Ultrafast Tablet Imaging Made Practical with the Novel Use of QCL Sources Coupled with Machine Learning-Based Analysis Algorithms
The composition of pharmaceutical tablets and the distribution of the ingredients therein can be determined using chemical imaging performed by vibrational microscopy. Doing so provides valuable...
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Photoacoustic Remote Sensing: A New Absorption-Based Microscopy for Assessment of Subcellular Structures
Optical absorption is a desirable imaging contrast because a wide variety of biomedical and industrial targets absorb light, including RNA, DNA, blood, lipid, metals, and some gas molecules such as...
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Emerging Clinical Applications of LED-Based Photoacoustic Imaging
Photoacoustic imaging is a hybrid technique with combined optical contrast and ultrasound-based resolution and imaging depth, offering tremendous potential in detection and treatment monitoring of...
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Algorithms Al Fresco: Challenges in Visualizing High Dimensional Flow Cytometry Data
The last 20 years has seen an explosion in the technological capabilities of flow cytometers. Today it is routine to measure 20 fluorescent particles per cell, with cutting edge instrumentation...
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Multiphoton Imaging in Neuroscience
Multiphoton imaging in neuroscience has much evolved from the initial two-photon microscope that Winfried Denk built in Watt Webb’s lab at Cornell University in the late 1980s, which made the...
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Optical Technologies Are Poised to Guide Cancer Surgery in Low- to Middle-Income Regions
A majority of noncommunicable diseases — including almost all types of cancer — are treated with some sort of surgery. According to the World Health Organization (WHO), 4.8 billion people...
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KEYNOTE: FLIM in Surgical Oncology
Marcu reviews the development of clinically compatible fluorescence lifetime imaging (FLIM) technology and applications in surgical oncology. Emphasis is placed on the integration of FLIM in surgical...
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Scientific CMOS Drives Discovery in Live-Tissue Applications
Advancements in camera technology have pushed the quest for knowledge into live imaging of cellular processes and even into the workings of the human brain, with new applications in neuroscience....
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Macroscopy FRET FLI Monitors Cancer Drug-Target Engagement in Vivo
The main goal of Barroso and her colleagues’ research is to accelerate preclinical drug discovery by developing novel imaging assays to screen and optimize the delivery of targeted anti-cancer...
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BabyGlucoLight Uses Diffuse Optics to Link Glucose Levels at Birth with Early Brain Development
Very preterm newborns are more susceptible to changes in glucose levels (hypo- or hyperglycemia) during the first weeks postpartum. Achieving optimal glycemic control in this population is, however,...
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Getting Outstanding Results From Multispectral TCSPC Fluorescence Lifetime Imaging
Heitz discusses how scientific results from various cutting-edge studies performed by Becker & Hickl and the company’s collaborators were generated and what to consider when planning...
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Fluorescence Techniques Help Preserve Parathyroid Function During Thyroid Surgery
Hypoparathyroidism is the most common complication after total thyroidectomy and is the result of the inadvertent devascularization of parathyroid glands. To help address this issue, researchers have...
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Intelligent Diagnostic Systems: Key Factors for the Successful Integration of AI Algorithms into Medical Devices
Artificial intelligence algorithms can significantly enhance the capabilities of medical devices, but key considerations need to be made during device development in order for users to get the most...
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RCM-OCT Enhances Skin Cancer Diagnosis and Therapy Guidance Through Hand-Held Imaging
Advancements in optical imaging in recent years have enabled faster and more reliable noninvasive assessment of skin lesions, especially of basal cell carcinomas. Among various technologies, optical...
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Computational 3D Microscopy with Optical Coherence Refraction Tomography
Through decades of technological development, optical coherence tomography (OCT) has become faster and more sensitive as a biomedical volumetric imaging modality. However, it still suffers from...
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Multimodal Functional OCT for Clinical Assessment of Oral Soft and Hard Tissue Conditions
Optical coherence tomography (OCT) is a noninvasive technique providing cross-sectional images of tissue microstructures and functional information with high resolution. Subhash reports on the...
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KEYNOTE: Optical Coherence Tomography and Multimodal Characterization of Bacterial Biofilms in Humans and Their Implications for Disease
Biofilms are comprised of communities of micro-organisms encapsulated in a matrix of extracellular polymeric substances. This matrix serves to isolate and protect the micro-organisms from harmful...
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Semantic and Instance Segmentation of Microscopic Images Using Pretrained Neural Networks
Robust segmentation of microscopic images is the foundation for the subsequent analysis of the image content and hence the (biological) properties of the sample. In addition to semantic segmentation,...
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Probes Provide Supermultiplexed Imaging of Tissues and Systems
Biological systems with intrinsic complexity require multiplexing techniques to comprehensively describe the phenotype, interaction, and heterogeneity. However, fluorescence can only image two to...
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KEYNOTE: Deep Learning-Enabled Computational Microscopy and Diffractive Imaging
Ozcan provides an overview of his recent work on using deep neural networks in advancing computational microscopy and sensing systems. He also covers the systems' biomedical applications, including...
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MediSCAPE Microscopy Enables Label-Free, 3D Histological Imaging in Vivo
The microstructure and cellular organization of tissues have been imaged to differentiate between tissue types in their normal and diseased states since the 19th century. However, despite major...
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April 2024
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