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MORE MICROSCOPYMICROSCOPY FEATURES
Optimizing Probe Positioning for Life Science Research Oct 12, 2018 — Photonics technologies enable life scientists to probe samples in the increasingly sophisticated study of processes ranging from neuron signaling to heart muscle contraction, as well as cells and cellular development. As research continues at increasingly finer levels of resolution, the requirements for optomechanical positioning become ever more demanding. Positioning equipment manipulates the probes used to interact with biological samples. This includes positioning a light probe, such as
BioPhotonics, Dec 2018
Miniaturization, Increased Resolution Drive Microscopy’s Future Sep 12, 2018 — Miniature fluorescence microscopes and other system components, such as liquid lenses, are among emerging microscopy advancements that are bettering optical inspection in areas including the life sciences and machine vision. Now, such technology is...
BioPhotonics, Oct 2018
SHG Microscopy Brings Live Cells into 3D Focus Sep 10, 2018 — Second-harmonic generation (SHG) microscopy brings the imaging of select biomolecular assemblies into 3D focus. It highlights biomolecules that follow specific structural organization within biological tissues, and complements two-photon excited...
BioPhotonics, Oct 2018
Photothermal IR Spectroscopy Boosts Chemical Microscopy, Expands Applications Aug 15, 2018 — Current bioanalysis largely relies on tissue homogenization and separation, followed by various assays. Without spatial and temporal dynamics information, the way in which molecules execute their functions in a living system remains unknown....
BioPhotonics, Sep 2018
Fluorescence Microscopy Unravels Morphogenesis, Function of Lymph System May 24, 2018 — The lymphatic system is an underinvestigated part of the vascular system. A team led by Friedemann Kiefer at the European Institute for Molecular Imaging (EIMI) at the University of Münster in Germany is aiming to change that in ongoing studies...
BioPhotonics, Aug 2018
Double-Helix Point Spread Function Delivers Precise Extended-Depth Microscopy May 23, 2018 — Light microscopy is a powerful method used in many scientific disciplines, including the life sciences, to visualize finer details in samples. The use of fluorescence enables specific targeting and labeling of biomolecules and other chemicals....
BioPhotonics, Aug 2018
Continuously Variable Bandpass Filters Aid Optics and HSI May 14, 2018 — Hyperspectral imaging (HSI) has been in use for a couple of decades in applications such as satellite imaging and air reconnaissance. Despite its widespread use, there is a lack of clarity of what “hyperspectral” encompasses. Sometimes techniques...
Photonics Spectra, Jun 2018
Nonconfocal 3D Microscopy Combines Real-Time Images with Depth of Focus Apr 9, 2018 — Stereo 3D microscopes produce real-time 3D images, but they are usually limited to low-magnification applications, such as dissection. Most compound light microscopes produce flat, 2D images because high-magnification microscope lenses have...
BioPhotonics, Jun 2018
Multiphoton Microscopy Sets the Standard for Live-Cell Imaging Mar 12, 2018 — Multiphoton imaging is widely used for live-cell imaging. Many of the applications are in neuroscience, where the overarching trends involve deeper imaging using longer wavelengths. These trends are the leading drivers behind the latest generation...
BioPhotonics, Apr 2018
Continuously Variable Bandpass Filters Aid Optics and HSI Jan 24, 2018 — Hyperspectral imaging (HSI) has been used for a couple of decades in applications such as satellite imaging, air reconnaissance and other markets that are not price sensitive. Still, there is no clear definition of the term. Sometimes techniques...
EuroPhotonics, Mar 2018
Prism Awards Honor Industry’s Top Innovators Jan 16, 2018 — What do the world’s smallest FTIR spectrometer and a smartphone add-on sensor for noncontact bioimaging have in common? The 2018 Prism Awards for Photonics Innovation. These products are among 30 finalists for the awards that recognize the...
BioPhotonics, Jan 2018
Histology Breaks a Speed Barrier Jan 11, 2018 — High-bandwidth sensing has brought data volumes previously unconsidered into everyday tools. Tightly coupled with this are modern, powerful computational approaches, including machine learning and scalable computation, that enable intelligent data...
BioPhotonics, Mar 2018
SPIE BiOS Highlights Biomedical Optics Jan 3, 2018 — SPIE BiOS has been hailed “the most important biomedical optics conference you can attend in 2018.” The world’s largest biophotonics, biomedical optics and imaging conference, it offers the latest research on topics such as...
BioPhotonics, Jan 2018
MUSE: Simple Slide-Free Microscopy Dec 8, 2017 — Even in this era of molecular medicine, conventional light microscopy remains the principal contributor to cancer diagnostics and also serves to guide surgical procedures, monitor disease activity and follow therapy responses over time. Although...
BioPhotonics, Jan 2018
Silicone Immersion Objectives Boost 3D Live-Cell Imaging Dec 6, 2017 — Refractive index mismatch and resulting spherical aberration has historically plagued researchers interested in long-term, live-cell imaging at high resolution. The use of silicone oil objectives helps mitigate this mismatch, as the refractive index...
BioPhotonics, Jan 2018
Photonics West Brings Together Industry’s Best, Brightest Nov 1, 2017 — With three conferences — BiOS, LASE and OPTO — and two exhibitions, SPIE Photonics West is the world’s largest annual event for the photonics, laser and biomedical optics industries. And it’s just around the corner —...
Photonics Spectra, Dec 2017
DGC Helps Illuminate Mechanisms of Alcohol Dependency Oct 10, 2017 — Imaging transparent, colorless specimens has always presented a challenge in optical microscopy. In many applications, it is not desirable or even possible to use fluorescent dyes, stains or transgenic probes to render target objects more visible....
BioPhotonics, Dec 2017
Silicone Immersion Objectives Answer the Call for Higher Resolution Sep 21, 2017 — Refractive index mismatch, and resulting spherical aberration, has historically plagued researchers interested in long-term, live-cell imaging at high resolution. The use of silicone oil objectives helps mitigate this mismatch as the refractive...
Photonics Spectra, Nov 2017
3D Mapping of Neural Circuits In Vivo Opens the Window on Neurological Disease Sep 5, 2017 — Despite extensive research, brain function and neurological diseases are poorly understood. Complexities arise from the quantity of neurons in the brain and from the densely interconnected networks of intermixed cell types. Tools neuroscientists...
BioPhotonics, Oct 2017
Single-Molecule Localization Blazes New Paths for Microscopy Sep 1, 2017 — Fluorescence microscopy has proven itself to be an indispensable method in the modern biological toolkit. The use of visible-wavelength fluorophores allows for relatively noninvasive imaging. While the resolution of conventional optical microscopy...
BioPhotonics, Oct 2017
Forensic Microscopy Expands Its Reach Aug 28, 2017 — The field of forensic microscopy is more than a century old. Though practitioners say their profession is far less glamorous than its portrayal in popular TV crime and courtroom shows, forensic investigation remains a powerful tool for learning the...
BioPhotonics, Oct 2017
Making the Connection: Optics, Neural Activity and Behavior SEAD DORIC, DORIC LENSES An international army of neuroscientists is trying to better understand the inner workings of the brain by exploring the correlations between neural activity and behavior of freely moving or partially restrained lab animals. The best method for...
BioPhotonics, Sep 2017
LEDs in Microscopy: An Emerging Research Tool Jul 21, 2017 — LED technology is playing an increasingly important role in lighting up our lives. Over the past 50 years, the technology has expanded from simple indicators in electronic gadgets to saving our planet terawatts of power by ousting incandescent bulbs...
EuroPhotonics, Sep 2017
Ultrafast Optics Faces Challenges Outside of Research Labs Jul 10, 2017 — Ultrafast optics is currently a scientifically dominated area with a lot of dynamics in both research and development. Often, complex setups make it challenging to create compact devices that can be employed for applications outside of the...
EuroPhotonics, Sep 2017
Smartphone Fluorescence Microscopy Allows Cost-Effective Molecular Diagnostics Jun 7, 2017 — Lack of diagnostic tools in resource-limited settings remains one of the major obstacles to disease diagnosis and treatment in the developing world. Although significant progress has been made in the availability of highly sensitive and specific...
BioPhotonics, Aug 2017
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