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Histology Breaks a Speed Barrier Jan 11, 2018 — High-bandwidth sensing has brought data volumes previously unconsidered into everyday tools. Tightly coupled with this are modern, powerful computational approaches, including machine learning and scalable computation, that enable intelligent data interpretation with virtually no human in the loop. Today’s optical instruments, which have integrated software and compute layers, are outpacing human bandwidth and forcing their human designers and end users to operate more like orchestrators
BioPhotonics, Mar 2018
SPIE BiOS Highlights Biomedical Optics Jan 3, 2018 — SPIE BiOS has been hailed “the most important biomedical optics conference you can attend in 2018.” The world’s largest biophotonics, biomedical optics and imaging conference, it offers the latest research on topics such as...
BioPhotonics, Jan 2018
MUSE: Simple Slide-Free Microscopy Dec 8, 2017 — Even in this era of molecular medicine, conventional light microscopy remains the principal contributor to cancer diagnostics and also serves to guide surgical procedures, monitor disease activity and follow therapy responses over time. Although...
BioPhotonics, Jan 2018
Silicone Immersion Objectives Boost 3D Live-Cell Imaging Dec 6, 2017 — Refractive index mismatch and resulting spherical aberration has historically plagued researchers interested in long-term, live-cell imaging at high resolution. The use of silicone oil objectives helps mitigate this mismatch, as the refractive index...
BioPhotonics, Jan 2018
Photonics West Brings Together Industry’s Best, Brightest Nov 1, 2017 — With three conferences — BiOS, LASE and OPTO — and two exhibitions, SPIE Photonics West is the world’s largest annual event for the photonics, laser and biomedical optics industries. And it’s just around the corner —...
Photonics Spectra, Dec 2017
DGC Helps Illuminate Mechanisms of Alcohol Dependency Oct 10, 2017 — Imaging transparent, colorless specimens has always presented a challenge in optical microscopy. In many applications, it is not desirable or even possible to use fluorescent dyes, stains or transgenic probes to render target objects more visible....
BioPhotonics, Dec 2017
Silicone Immersion Objectives Answer the Call for Higher Resolution Sep 21, 2017 — Refractive index mismatch, and resulting spherical aberration, has historically plagued researchers interested in long-term, live-cell imaging at high resolution. The use of silicone oil objectives helps mitigate this mismatch as the refractive...
Photonics Spectra, Nov 2017
3D Mapping of Neural Circuits In Vivo Opens the Window on Neurological Disease Sep 5, 2017 — Despite extensive research, brain function and neurological diseases are poorly understood. Complexities arise from the quantity of neurons in the brain and from the densely interconnected networks of intermixed cell types. Tools neuroscientists...
BioPhotonics, Oct 2017
Single-Molecule Localization Blazes New Paths for Microscopy Sep 1, 2017 — Fluorescence microscopy has proven itself to be an indispensable method in the modern biological toolkit. The use of visible-wavelength fluorophores allows for relatively noninvasive imaging. While the resolution of conventional optical microscopy...
BioPhotonics, Oct 2017
Forensic Microscopy Expands Its Reach Aug 28, 2017 — The field of forensic microscopy is more than a century old. Though practitioners say their profession is far less glamorous than its portrayal in popular TV crime and courtroom shows, forensic investigation remains a powerful tool for learning the...
BioPhotonics, Oct 2017
Making the Connection: Optics, Neural Activity and Behavior SEAD DORIC, DORIC LENSES An international army of neuroscientists is trying to better understand the inner workings of the brain by exploring the correlations between neural activity and behavior of freely moving or partially restrained lab animals. The best method for...
BioPhotonics, Sep 2017
Ultrafast Optics Faces Challenges Outside of Research Labs Jul 10, 2017 — Ultrafast optics is currently a scientifically dominated area with a lot of dynamics in both research and development. Often, complex setups make it challenging to create compact devices that can be employed for applications outside of the...
Photonics.com, Sep 2017
Smartphone Fluorescence Microscopy Allows Cost-Effective Molecular Diagnostics Jun 7, 2017 — Lack of diagnostic tools in resource-limited settings remains one of the major obstacles to disease diagnosis and treatment in the developing world. Although significant progress has been made in the availability of highly sensitive and specific...
BioPhotonics, Aug 2017
Interweaving Photonics Research, Industry May 4, 2017 — Laser World of Photonics provides a spotlight for promising newcomers, industry veterans and innovative companies. And with tens of thousands of people from countries around the globe attending the show, that spotlight is huge. In 2015, the biennial...
Photonics Spectra, Jun 2017
Demanding Applications Call for Reflective Objectives May 3, 2017 — Laser systems costs are falling, leading to their increased use in a host of demanding applications from machining to hyperspectral imaging. Often in these cases, a small, diffraction-limited spot size is required. When specifying a microscope...
Photonics Spectra, Jun 2017
Fluorescence Imaging Enters the Surgical Suite Apr 12, 2017 — In the last decade, researchers have worked extensively on medical devices and applications that measure the spectral response of tissue to various wavelengths of light. These applications, in a lab or proof-of-principle setup, have proven the...
BioPhotonics, Jun 2017
Member Exclusive
FLIM Delivers Intracellular Images Based on Differences Apr 6, 2017 — Fluorescence lifetime imaging microscopy (FLIM) enables researchers in the life sciences to get information from live specimens about interactions on the molecular scale. The technique captures the differences in the excited state decay rate from a...
BioPhotonics, Jun 2017
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Challenges and Opportunities in Superresolution Mar 28, 2017 — Much of our understanding of biology has come from our ability to image biological processes and structures through microscopes. But until recently, the imaging of intracellular structures and activities has been constrained by the optical...
BioPhotonics, Jun 2017
Advances in Surgical Microscopes Pave the Way to Improved Outcomes Mar 2, 2017 — By integrating intelligence, video, intraoperative-imaging and navigation technologies, today’s surgical microscopes provide surgeons with insights to improve their decision-making at the point of care and provide patients with the best...
BioPhotonics, Apr 2017
Probing Cancer by Exploiting Spontaneous and Stimulated Raman Scattering Mar 1, 2017 — Most of our knowledge about the chemical contents in cancer cells or cancerous tissue is obtained from in vitro analysis of fixed cells and tissues or homogenates. These in vitro assays identify the presence of molecules, but do not provide...
BioPhotonics, Apr 2017
Modular Accessories Expand Fluorescence Microscope Capabilities Jan 25, 2017 — Despite the superior spatial resolution of complementary newer technologies such as atomic force microscopy (AFM), fluorescence microscopy remains a preeminent technology in the life sciences. Fluorescence detection offers a uniquely simple method...
BioPhotonics, Jan 2017
Superresolution Microscopy: An Imaging Revolution Jan 18, 2017 — Superresolution optical microscopy has been one of the most momentous developments in the life sciences over the last decade — and its evolution is ongoing. Progress has been so rapid and significant that it has been dubbed by some observers as “the...
Photonics.com, Mar 2017
Breaking the Speed Barrier for High-Fidelity, Large-Area Confocal Scanning Dec 16, 2016 — The need to image microstructures over very large areas is driving the next generation of instrumentation in microscopy. The challenge is complex: How can very large areas be scanned quickly and with high fidelity? Conventional wide-field...
BioPhotonics, Jan 2017
Fluorescence Correlation Spectroscopy — Going Beyond the Diffraction Limit Oct 11, 2016 — The combination of short measurement times along with free position or scanning of the observation spot makes fluorescence correlation spectroscopy an excellent tool for investigating diffusion heterogeneity over time and space.
BioPhotonics, Dec 2016
In Vitro Diagnostics, Immunology Spurring Advances in Flow Cytometry Oct 3, 2016 — Cells are the building blocks of organisms. From yeast and bacteria to elephants and whales, cells are the fundamental units of both biological structure and function. They have long been the subject of intense study: to better understand how they...
Photonics Spectra, Nov 2016
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