NAGOYA, Japan, Oct. 23, 2019 — A team at Nagoya University’s Institute of Transformative Bio-Molecules has developed a marker molecule that bypasses the problem of photobleaching in STED microscopy. It’s allowing an unprecedented view of live mitochondria, which could help researchers better understand, diagnose, and potentially cure human mitochondrial disease. The new marker molecule — MitoPB Yellow — is absorbed by the inner membrane of mitochondria, which includes the cristae (fold-like structures), and has demonstrated a long lifetime under a STED beam. According to the researchers,...Read full articleRelated content from Photonics MediaARTICLESGraphene Enables Live Cell Imaging at the NanoscaleResearchers at the Daegu Gyeongbuk Institute of Technology (DGIST) have introduced a method for analyzing subcellular structures using graphene. The work holds implications for the research of...Photonics.com 2/18/2021Microscopy Method More Sensitive for Viewing Live CellsResearchers from the University of Tokyo have developed a way to increase the extent and types of information they are able to ascertain about the insides of living cells by using existing microscopy...BioPhotonics Mar/Apr 2021 IssueNIH Researchers Speed Image Processing for Fluorescence MicroscopyAdvances in image processing techniques could reduce post-processing time for highly complex microscopic images up to several thousandfold, based on work done by a research team at the National...BioPhotonics Sep/Oct 2020 IssueIntravital Imaging Provides Insight into Liver Disease ProgressionThe high-resolution, 3D-viewing capabilities provided by a new microscopy method from the Korea Advanced Institute of Science and Technology (KAIST) could lead to insights into nonalcoholic fatty...BioPhotonics Nov/Dec 2020 IssuePRODUCTSKeylight™ OEM Light SourceKeyLight™ illumination sources for fluorescence microscopy is the perfect solution to integrate into your equipment. Phoseon's proprietary LED solutions offer intense, broad-spectrum...Promoted Content July 2020 Issue8-Channel Illumination Control in SoftwareCoolLED’s ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging can now be controlled in Olympus/Evident cellSens imaging software version 4.1. This is...Promoted Content June 2022 IssueLED Illuminators for ‘Green’ LabsCoolLED, a global expert in LED microscopy illumination, is helping labs become more sustainable by reducing the environmental impact of its popular pE-300 Series Illumination Systems, which is...Promoted Content March 2021 IssueNeed Something a Bit Different?CoolLED’s Amora Series for custom microscopy illumination is based on an established portfolio of off-the-shelf products, adapted to offer unparalleled customization opportunities. This...Promoted Content March 2022 IssuePHOTONICS HANDBOOK ARTICLESNanopositioning: A Step Ahead: It is almost a cliché among students of creativity that innovation occurs at the intersection of fields. Since nanopositioning is a discipline that has enabled swiftly evolving application arenas as diverse as materials science, genomics, photonics, defense, biophysics, and semiconductors, it’s unsurprising that its pace of innovation is nothing short of blistering in recent years.By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...Photonics HandbookAspheric Lenses: Design Considerations: This first of two articles will cover design and manufacturing options for aspheres; the second will include more detail on manufacturing and testing processes. These articles will provide the tools optics designers need to tailor their designs to the appropriate manufacturing process and to optimize the cost of component fabrication.Aspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookLasers for Microscopy: Major Trends: In order for biologists, drug developers, clinical lab professionals and other scientists to fully exploit new microscopy techniques and applications, parallel developments in laser technology are often required. Laser manufacturers are responding with products optimized to match the needs of these applications.Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light Sources: Metal halide and LED light sources are changing the illumination landscape in microscopy. Brighter, easier to use and growing in application, they are driving new options in fluorescence, conventional bright-field and other contrast techniques.As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookWHITEPAPERSUsing Imaging Colorimeters to Correct OLED, MicroLED, and Other Emissive Displays for Production Efficiency and YieldsImaging colorimeters can improve OLED and microLED display production by ensuring visual quality of displays — measuring brightness and color uniformity at the pixel and subpixel level to correct...Photonics.com 1/14/20214 Steps to Optimize the Optics in Automated Imaging InstrumentsOptimize the performance and cost of your automated optical imaging system with 6 key equations for selecting an imaging sensor, objective lens, Z-focusing nano-positioning stage and XY sample...Photonics.com 5/17/2021Automated Solutions for SAE Standard HUD MeasurementHead-up display (HUD) technology is one of the largest growth areas in the automotive market, and standard measurement criteria are rapidly being defined to evaluate augmented projections for visual...Photonics.com 1/14/2021Methods for Measuring Display Defects and Mura as Correlated to Human Visual PerceptionHuman vision and perception are the ultimate determinants of display quality, however human judgment is variable, making it difficult to define and apply quantitatively in research or production...Photonics.com 1/14/2021WEBINARSTechniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 3/21/2013Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 1/24/2019Photonics Spectra Conference 2022: January 10 - 13Photonics Media will host its second annual Photonics Spectra Conference Jan. 10-13. The virtual event will comprise four technology tracks — Lasers, Optics, Sensors and Detectors, and Imaging...Photonics.com 1/10/2022Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 6/5/2013PHOTONICS DICTIONARY TERMSLight Sheet Fluorescence Microscopy (LSFM)Also known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...EDU.photonics.com 3/5/2018optical coherence tomography (OCT)A noninvasive (typically medical) optical imaging acquisition technique that uses light waves to form distinct, three dimensional, layered cross-sectional images of an optical scattering media (i.e....EDU.photonics.com 3/5/2018femtosecond laserA type of ultrafast laser that creates a minimal amount of heat-affected zones by having a pulse duration below the picosecond level, making the technology ideal for micromachining, medical device...EDU.photonics.com 3/5/2018laser guide starAn artificial star used to aid in adaptive optics imaging of the sky. The guide star is provided from a telescope system on the ground and is directed into the imaged region. The wavefront...EDU.photonics.com 3/5/2018MEDIASupporting the Photonics Industry from the Laboratory - LIGHT MATTERS 01.2018On this month's episode of Light Matters, we take you to central Massachusetts as Worcester Polytechnic Institute and Quinsigamond Community College take on a comprehensive joint photonics laboratory...Photonics.com 1/18/2018Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...Photonics.com 1/18/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 2/21/2018Capasso Group Embeds, Projects Independent Images on MetasurfaceMembers of the Capasso Group at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have successfully encoded multiple holographic images in a metasurface. The separate...Photonics.com 8/9/2018PHOTONICS BUYERS' GUIDE CATEGORIESMedical/Biomedical Light SourcesMicropositionersUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Projection MicroscopesCOMPANIESLaCroix Precision OpticsOptics that Defend, Build, Cure and Discover The LaCroix name is synonymous with quality precision optics. Since 1947, three generations of family leadership have placed LaCroix Precision Optics...Photonics Buyers' GuideAndor TechnologyWe are global leaders in the development and manufacture of high performance scientific digital cameras for academic, industrial and government applications. Through continuous dialogue with our...Photonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideDiverse Optics Inc.Diverse Optics transforms optical systems from expensive, heavy, and complicated to commercially viable, lightweight, and simple. We manufacture custom precision polymer optic components and...Photonics Buyers' Guide