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BioPhotonics: Jul/Aug 2018

BioPhotonics
 Jul/Aug 2018


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FEATURES
Lensless Cameras May Offer Detailed Imaging of Neural Circuitry Understanding brain function at the scale of individual neurons could open the door for advanced understanding of animal and human behavior and the mechanisms of neurological disorders such as...
Fluorescence Microscopy Unravels Morphogenesis, Function of Lymph System The lymphatic system is an underinvestigated part of the vascular system. A team led by Friedemann Kiefer at the European Institute for Molecular Imaging (EIMI) at the University of Münster in...
Double-Helix Point Spread Function Delivers Precise Extended-Depth Microscopy Light microscopy is a powerful method used in many scientific disciplines, including the life sciences, to visualize finer details in samples. The use of fluorescence enables specific targeting and...
Member Exclusive
Point-of-Care Optics Helps Halt the Spread of Infectious Diseases Early diagnosis is the critical starting point to a better outcome for a patient. It allows effective treatment to start earlier, giving the patient the best possible prognosis. Prompt diagnosis also...
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EDITORIAL
Deepening Capabilities In our cover story this month, Katie Heiser and Leslie Kimerling of Double Helix Optics write about a device that integrates depth information with increased resolution. For such work, Double Helix was named a top winner of the first Luminate NY awards. The award comes with a $1 million investment and is sponsored by an accelerator program in Rochester, N.Y., designed to speed innovation and time...
BIOPINION
Open-Source Biophotonics is Better For All Biophotonics has revolutionized many research fields, with direct effects on human well-being. Obviously, imaging requires microscopes and contrast agents. An open-source, sharing-driven model of technology development and dissemination can foster discoveries at a faster rate than under the status quo. For the past decade, the Janelia Research Campus at the Howard Hughes Medical Institute (HHMI)...
BIOSCAN
Graphene Biointerface Optically Controls Heart Cells Researchers have developed a technique that allows them to speed up or slow down human heart cells, on command, by shining a light on the cells and varying the light intensity. The optical stimulation platform does not require genetic modification of cells but instead makes use of the optoelectronic properties of graphene, that is, graphene’s ability to efficiently convert light into...
Lidar Helps Yellowstone Manage Threatened Ecosystem Lidar could offer a fast, efficient way to locate and capture lake trout, an invasive, nonnative fish that is upending the ecosystem in Yellowstone Lake. Aircraft-mounted lidar could allow lake...
QCL-based IR Microscopy Performs Rapid Cancer Diagnosis A quantum cascade laser-based IR microscope was used for the rapid, label-free classification of colorectal cancer tissues. IR imaging has been shown to be a reliable method for tissue...
NIH Researchers Merge Microscopy Techniques for Faster Images To create sharper images more quickly, researchers blended instant structured illumination microscopy (iSIM) with total internal reflection fluorescence microscopy (TIRFM). The new technique, called...
Triboluminescence Used to Test for Drug Efficacy An instrument has been developed that uses triboluminescence (TL) to enable selective detection of trace crystallinity within amorphous solid dispersions, used in the preparation of pharmaceutical...
Optogenetic Tool Controls Voltage-Gated Calcium Channels An optogenetic tool has been developed for controlling voltage-gated calcium (CaV) channels to enable photo-tunable modulation of CaV channel activity in excitable mammalian cells. The tool, called...
Light-Based Approach Manages Chronic Neuropathic Pain Researchers have developed a light-based method that could be used to manage neuropathic pain. The technique was tested in mice. Researchers from the European Molecular Biology Laboratory (EMBL) Rome...
AO-LLSM Microscope Achieves Aberration-Free Imaging Scientists have combined lattice light-sheet microscopy (LLSM) with adaptive optics (AO) to capture high-resolution 3D movies of cells deep within living systems. The AO-LLSM microscope enables cells...
Microsensor Could Help Individualize Dialysis Treatment A new microsensor could make it possible to directly monitor and adjust the composition of kidney dialysis fluid (dialysate) — an important step toward customizing dialysis to the individual...
RAPIDSCAN
Luminate NY Names Double Helix Top Winner of Competition's First Round Double Helix Optics was named the overall winner in the first round of the Luminate NY competition. The Boulder, Colo.-based company will receive $1 million in follow-on funding from New York state through the Finger Lakes Forward Upstate Revitalization Initiative. As the award stipulates, Double Helix will commit to establishing operations in Rochester for at least the next 18 months. Double...
Zebra Medical Announces Algorithm Approval Health care imaging analytics developer Zebra Medical Vision has announced CE (European Conformity) regulatory approval of its newest algorithm to be included in its deep learning imaging analytics...
Baby Sleep Monitor Developer Nanit Secures $14M in Funding Nanit, a smart baby monitor developer that uses computer vision technology to help baby sleep development, has secured $14 million in Series B financing led by Jerusalem Venture Partners (JVP). With...
KARL STORZ Launches Blue Light Bladder Cancer Treatment Following the approval of a supplemental new drug application and a premarket approval supplement from the U.S. Food & Drug Administration, KARL STORZ Endoscopy-America Inc. has launched the...
PicoQuant Opens Chinese App Center Optoelectronics developer PicoQuant GmbH has opened its Application Center China, a showroom for time-resolved fluorescence test measurement technology based in China’s Optical Valley. The new...
Nuclear Medicine, Molecular Imaging Industry Group Forms The Society of Nuclear Medicine and Molecular Imaging’s (SNMMI’s) Value Initiative Industry Alliance has been established to connect corporate members to the future of nuclear medicine...
UCI’s Biophysicist Receives $2M Grant for Insect Control Research Todd Holmes, professor of physiology and biophysics at the University of California, Irvine, has been awarded a competitive five-year $2.1 million Outstanding Investigator Award/Maximizing...
Cellmic Patent Aims to Grow Leti Portfolio Leti, a research institute at CEA Tech, and Cellmic LLC, a company that leverages patient health care with smartphones and biophotonics, have joined forces to accelerate the market adoption of...
UFC Develops Quantum Material That Uses, Stores Energy at Subatomic Level The San Antonio Endovascular & Heart Institute (SAEHi), a practice specializing in diagnosing, treating, managing, and researching diseases and disorders of the heart and vascular system, has...
Larson Named MSA Fellow David J. Larson, director of scientific marketing for material analysis technology developer CAMECA Instruments Inc., has been appointed a fellow of the Microscopy Society of America (MSA). The MSA...
UA Engineer Inducted into AIMBE Matthew Becker, who holds the W. Gerald Austen Endowed Chair of Polymer Science and Polymer Engineering at the University of Akron (UA), was inducted into the College of Fellows by the American...
Lensar System Receives FDA Clearance Ocular laser developer Lensar Inc. has received 510(k) clearance from the U.S. FDA for its LENSAR laser system with Streamline IV, expanding the platform’s capabilities to include the creation...
Certara Acquires Analytica Laser Drug development consultant company Certara LP has acquired Analytica Laser, a consultancy for medicine and health technology. ”We are delighted to be joining Certara, a recognized leader in...
POST SCRIPTS
Laser ‘Smells’ Diseases via Breath Analysis A noninvasive laser that can “smell” could make diagnosing diseases easier. University of Adelaide researchers in Australia have created a laser that can differentiate between gases within a sample. The new device could be used for environmental monitoring and detecting industrial contamination, and also to diagnose disease by “smelling” a person’s breath. The device...
PRODUCTS
Bioinert The µ-Dish from ibidi GmbH is a 35-mm Bioinert, providing a solution for scientists who want to combine long-term culture and high-resolution microscopy of living spheroids or suspension cells...
ibidi GmbH
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Tunable Quantum Cascade Laser A high-power tunable quantum cascade laser from DRS Daylight Solutions Inc. spans 3.3 to 3.8 µm and covers the essential C-H stretch molecular vibration band. This development follows the...
DRS Daylight Solutions
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Measurement Accessory The Cryosphere commercial accessory from Edinburgh Instruments Ltd. is designed for the FLS1000 spectrometer and allows the measurement of photoluminescence quantum yield from 77 to 500 K. The...
Edinburgh Instruments Ltd.
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Smart Laser Driver The Taiko PDL M1 smart laser driver from PicoQuant GmbH is designed for the most demanding applications in the life and material sciences, semiconductor diagnostics, and laser-ranging. The...
PicoQuant GmbH
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Violet Laser Diode The HL40071MG violet laser diode from Ushio has been announced by ProPhotonix Ltd. The HL40071MG provides a high optical output power of 300 mW at a wavelength of 405 nm, offering an ideal...
ProPhotonix Ltd.
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Beam Expanders TECHSPEC DA (divergent adjustable) fixed broadband beam expanders from Edmund Optics Inc. are optimized at a wide range of wavelengths for maximum flexibility, making them ideal for use with...
Edmund Optics Inc.
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Clinical Laser System Software HT Laser 6 software from Hamilton Thorne Ltd. is a laser system software for clinical laser systems. HT Laser 6 features a new user interface to improve ease of use. Higher resolution video...
Hamilton Thorne Inc.
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NIR Fluorescence Imaging System The LIGHTVISION NIR fluorescence imaging system from Shimadzu Corp. is designed to support breast cancer treatment through the visualization of lymph vessels and blood vessels based on the detection...
Shimadzu Corp.
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High-Power LED Light Unit The PhotoSyn LED light unit is a photochemical energy source to promote reactions using Uniqsis's FlowSyn flow chemistry systems. Using this device with a FlowSyn system, labs can synthesize from lab... Request info >
Stereochemical Recognition Software The 2018 KnowItAll software and spectral databases from Bio-Rad Laboratories Inc. offer advanced stereochemical recognition and are able to interpret structures using traditional stereochemical...
Bio-Rad Laboratories Inc., Life Science Group
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Quartz-Bottomed Microplates Black Krystal UV quartz-bottomed microplates from Porvair Sciences Ltd. offer excellent optical transmission in the 185- to 1100-nm wavelength range, making them ideal for laboratories making...
Porvair Sciences Ltd.
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Hyperspectral Camera The 4100H hyperspectral camera from HinaLea Imaging is a high-precision camera with a built-in illumination source that captures high-resolution snapshot images. The camera yields a spectrum at...
HinaLea Imaging
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Microscopy Module The OptiRecon module for the Xradia Versa 500 series of 3D x-ray microscopes from Carl Zeiss AG allows users to quickly acquire high-quality images. OptiRecon enables users to choose quality...
Carl Zeiss Jena GmbH
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CMOS Bio-Optical Sensor The ULS24 ultralow-light CMOS bio-optical sensor from Anitoa Systems LLC is a single-chip device capable of 3 × 10−6 lux low-light detection. The ULS24 achieves a high level of...
Anitoa Systems LLC
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Lifetime Contrast Microscope The SP8 FALCON lifetime contrast microscope from Leica Microsystems GmbH can record lifetime contrast 10× faster than previous solutions. This lifetime information lets researchers...
Leica Microsystems GmbH
Carbon-Filtered Workstation The MicroFlow III from Hemco Corp. is a Class I ductless carbon-filtered workstation equipped with activated carbon filtration for fumes, odors, and nonhazardous chemical vapors. The 24-...
HEMCO Corp.
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Travel Stage The AV-2500 XY Flat-Top Extended Travel Stage from Applied Scientific Instrumentation Inc. is designed to fit the Zeiss Axio Observer microscope. The stage travels 250 mm in the X axis and 110...
Applied Scientific Instrumentation Inc.
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Custom Wavelength Selectors A new series of Custom Wavelength Selectors (CWS) from Spectrolight Inc. offers a cost-effective, off-the-shelf option for those needing narrowband transmission filters with custom bandwidth and...
SPECTROLIGHT Inc.
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Objective Focusing Stage The DOF-5 from Dover Motion is a low-cost objective focusing stage for automated imaging applications. The device features optical position feedback and servo drive controls integrated directly...
Dover Motion
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Photoluminescence Microspectroscopy Craic Technologies Inc. now offers photoluminescence microspectroscopy solutions. Users of Craic Technologies' 20/30 PV and Apollo II microspectrophotometers now have the ability to acquire...
CRAIC Technologies
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