Request InfoLeica Microsystems GmbHMANNHEIM, Germany, Dec. 5, 2014 — A new light-sheet module from Leica Microsystems enables observation of developing organisms in real time and 3-D using the company’s Leica TCS SP8 confocal microscope. The module uses a mirror device to deflect the illuminating light sheet at a 90° angle. This allows the integration of the light-sheet illumination and detection beam path into the vertical axis of the inverted microscope without compromising the confocal functionality. The combination of light sheet and confocal microscopy lets users employ familiar sample handling and combine confocal photo manipulation...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2023 IssueConfocal MicroscopeThe Dragonfly 600 confocal microscope from Andor Technology Ltd. allows users to image live specimens for days without phototoxicity or photobleaching. The device features a total internal...Photonics Spectra January 2023 IssueMicroscopy SoftwareThe Enersight software platform from Leica Microsystems is designed for microscope inspection and quality control. It allows users of any level to intuitively acquire images during inspection....BioPhotonics Mar/Apr 2022 IssueDigital Neurosurgery MicroscopeThe ARveo 8 digital visualization neurosurgery microscope from Leica Microsystems features fast processing speeds for augmented reality visualization. The device benefits an entire...Promoted Content July 2021 IssueModular Motion Control: MicroscopyModular Motion Control from the Micro to the Pico-scale. Build your own instrumentation for microscopy using Mad City Labs micropositioners and closed loop nanopositioners. Mad City Labs MMP series...ARTICLESBioPhotonics Sep/Oct 2021 IssueLattice Light-Sheet Microscopy Targets MalariaWith the help of a custom-built lattice light-sheet microscope, researchers at the Walter and Eliza Hall Institute (WEHI) captured high-resolution 3D video images of individual malaria parasites...Photonics.com 6/4/2021Metamaterial Lets Light-Sheet Microscopes See in SuperresolutionA hyperbolic metamaterial developed at the University of California, San Diego enables ordinary light-sheet microscopes to observe subcellular structures — in other words, enabling an ordinary...Photonics.com 2/4/2022Leica Opens Imaging Center in Heidelberg: Week in Brief: 02/04/22Researchers at the Australian National University achieved a fill factor of more than 86%, breaking their previous record. According to the researchers, the conversion efficiency of state-of-the-art...Photonics.com 3/17/2022SWIR Microscope to Enable Imaging Through Blood, Soft TissueCollaborators on a project called BetterView will develop a SWIR microscope that will overcome challenges faced by conventional visible spectrum surgical microscopes, such as seeing through blood,...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookMicroscopy Illumination: Considering Nonlaser Light Sources: Metal halide and LED light sources are changing the illumination landscape in microscopy. Brighter, easier to use and growing in application, they are driving new options in fluorescence, conventional bright-field and other contrast techniques.As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookNSOM: Discovering New Worlds: Near-field scanning optical microscopy (NSOM) is an optical microscopy technique capable of imaging objects with a resolution below the diffraction limit of conventional (far-field) microscopy; i.e., below approximately half the wavelength of the light used.NSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...Photonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal Microscopy: 3D imaging and ultrahigh resolution are ideal for the inspection of materials with defined surface finishes and textures.When evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...Photonics HandbookLasers for Microscopy: Major Trends: In order for biologists, drug developers, clinical lab professionals and other scientists to fully exploit new microscopy techniques and applications, parallel developments in laser technology are often required. Laser manufacturers are responding with products optimized to match the needs of these applications.Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 12/8/2022Sub 50 Femtosecond Pulse Lasers for Gentler Multiphoton MicroscopyFinding the ideal ultra-fast laser source for a multiphoton imaging setup is not trivial. It is a fine balance between peak power, pulse energy and laser wavelength. In this white paper we show that...Photonics.com 12/7/2021High-resolution deep brain imaging up to a depth of 1.4 mm using White Dwarf OPCPAA new microscopy technique developed at EMBL in Heidelberg enables highest imaging resolution for in vivo neuronal activity measurements deep in the brain, driven by a Class 5 Photonics White Dwarf...Photonics.com 12/2/2022FISBA READYBeam™ - Compact Powerful Laser SourceThe FISBA READYBeam™ is our answer to customers' increasing demand for compact, powerful, and reliable multicolor laser source that can be easily integrated into existing set-ups. The multicolor...WEBINARSPhotonics.com 6/17/2021Multi-Line Lasers or Laser Combiners: What Solution Is Best for Fluorescence Imaging?Fluorescence imaging is a key technique in both biomedical research and clinical diagnosis. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore imaging typically...Photonics.com 10/27/2022Laser Microbiopsy Could Provide Detailed Pathological Data with Limited Sample DamageWhile they are considered the gold standard for disease diagnosis, including cancer, tissue biopsy and histological evaluation have significant limitations. Among these limitations are a biopsy's...Photonics.com 10/23/2013Adaptive Optics for MicroscopyUpdate: Additional Questions from the Webinar Answered below. Enabling Structured Illumination Microscopy in Thick Tissue with Adaptive Optics Peter Kner University of Georgia ...Photonics.com 10/26/2021Quantum-Enhanced Superresolution Confocal MicroscopyFar-field optical microscopy beyond the Abbe diffraction limit is already a reality. Yet, while Abbe's theory was based on classical physics, quantum mechanical phenomena were only very recently used...PHOTONICS DICTIONARY+ TERMSEDU.photonics.com 9/8/2009laser confocal microscopeEDU.photonics.com 4/9/2018Golgi Staining TechniqueThe Golgi staining technique (also called the black reaction) makes it possible to look at the nervous system by rendering neurons visible under light microscopy. After a long process involving...EDU.photonics.com 3/5/2018optical stainingWith respect to microscopy, also called dispersive staining, optical staining the projection of colors through areas of a colorless specimen by color filters that are constructed to fit over the...EDU.photonics.com 9/8/2009zero-order filteringThe removal of the zero-order component of the Fourier spectrum distribution of an object with a small, opaque absorber or reflector in the Fourier plane, to produce images that appear bright on a...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 8/24/2022Ramacle® Software Highlight: Fast Mapping - Edinburgh InstrumentsThis Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 1/24/2022Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.PHOTONICS BUYERS' GUIDE CATEGORIESConfocal MicroscopesForensic MicroscopesInterference MicroscopesAn interference microscope is a special form of microscope used with perfectly transparent objects that are invisible under an ordinary microscope. The object is placed in one beam of a tiny...Medical/Biomedical MicroscopesCOMPANIESPhotonics Buyers' GuideBruker Nano SurfacesBruker Nano Surfaces is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. We cover...Photonics Buyers' GuideApplied Scientific Instrumentation Inc.Applied Scientific Instrumentation, Inc. (ASI) is a company committed to the advancement of science. Our engineers and technicians have years of experience in aiding researchers with their technical...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideAndor TechnologyWe are global leaders in the development and manufacture of high performance scientific digital cameras for academic, industrial and government applications. Through continuous dialogue with our...