Two-Photon Holographic Mesoscope Probes Activity Across Large Brain Regions
BERKELEY, Calif., Dec.18, 2023 — Recent advancements in two-photon (2P) mesoscopes have extended the field of view (FOV) for deep brain imaging, making it possible to image brain regions as large as 25 mm2. Until now, though, mesoscopes could only measure neural signals; they could not stimulate separated regions of the brain. To enable investigators to probe the inter-areal communication signals central to brain function, a team at the University of California, Berkeley (UC Berkeley) combined its aeroPULSE FS50