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medicine News
Deep Learning Model Helps Target Prostate Cancer Treatments to Individual
SEATTLE, April 2, 2024 — Approximately 250,000 men in the U.S. receive a prostate cancer diagnosis each year. While overall morbidity and mortality rates for this type of cancer are low, a subset of cases requires aggressive treatment. A machine-learning model developed by researchers at the University of Washington provides 3D segmentation of the glandular tissue structures that are used for prostate cancer risk assessment. The deep learning-based model for gland segmentation could help guide critical treatment
Ultrasensitive Chirality Detector Could Improve Drug Design and Efficacy
ORLANDO, Fla., April 1, 2024 — Researchers at the University of Central Florida (UCF) are investigating ways to enhance the development of new drugs and therapies. A tunable plasmonic platform from UCF, which enables accurate detection of chiral molecules, could help...
Photodynamic Method Boosts Antibiotics Against Drug-Resistant Bacteria
SÃO CARLOS, Brazil, Jan. 8, 2024 — Multidrug-resistant bacteria are considered a serious threat to infection control. Faced with the increasing difficulty of developing new antibiotics to combat resilient bacterial strains, scientists are turning to photodynamic inactivation (PDI), a...
Flow Cytometry Uncovers Predictive Biomarker for Severe COVID
MUNICH, Dec. 19, 2023 — Using image-based flow cytometry, researchers at the Technical University of Munich (TUM) identified a biomarker for predicting how serious a COVID-19 infection will be. They also developed a rapid test for assessing a patient’s risk of severe...
Label-Free Imaging Shows Dynamics of Intracellular Cargo Transport
DAEJEON, South Korea, Nov. 22, 2023 — Until now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of photobleaching and the visual isolation of cellular...
Light-Activated Tool Controls Protein Bonds and Tracks Cell Adhesion
TAMPERE, Finland, Nov. 20, 2023 — Optical tools can be used to activate biological functions, but with current methods the effects are slow to appear, and sustained effects require continuous light activation. As a result, these light-activation tools provide limited control of fast...
Lasers Improve Phototherapy-Drug Delivery Platform
BALTIMORE, Nov. 7, 2023 — Photoimmunotherapy targets cancer cells with microscopic, nano-engineered cancer drugs that are light-activated at the lesion site. Although the technology is increasingly used to treat metastatic cancer, tools to improve the effectiveness of...
Fluorescence Lifetime Imaging Could Improve Cancer Surgery Outcomes
BOSTON, Oct. 24, 2023 — Extreme precision is required to surgically remove a cancerous tumor without damaging the surrounding healthy tissue. Yet surgeons often must rely on their eyes and hands to determine where to cut. Fluorescence lifetime (FLT) imaging, developed at...
Deep Learning Delivers Optoacoustic Images in Real Time
MUNICH, Oct. 13, 2023 — High-quality medical imaging from multispectral optoacoustic tomography (MSOT) could be used to diagnose and evaluate a range of diseases, including breast cancer, Duchenne muscular dystrophy, IBD, and many more. However, the length of time...
Microscopy Method Detects Treatment-Resistant Cancer
BALTIMORE, Oct. 9, 2023 — Therapy-induced senescent (TIS) cells are cancer cells that become resistant to therapies and enter a dormant stage. These cells can emerge from dormancy and induce tumor resistance and relapse. To provide insight into how TIS cells evolve, it is...
Light-Activated Metal Particles Deliver Targeted Cancer Treatment
NOMI, Japan, Aug. 15, 2023 — A research group from Japan Advanced Institute of Science and Technology (JAIST) developed light-activatable, liquid metal (LM) nanoparticles for cancer diagnosis and treatment via photoimmunotherapy. The LM nanoparticles can target and destroy...
Novel Hybrid Material Facilitates Photon Upconversion
RIVERSIDE, Calif., June 26, 2023 — University of California, Riverside (UCR) researchers have designed a composite material that offers powerful photon upconversion capabilities and that could support a range of light-driven applications as a result. The composite is made from...
Light-Activated Molecular Machines Kill Pathogenic Fungi
HOUSTON, Feb. 9, 2023 — In the game-turned-TV series, The Last of Us, post-apocalyptic survivors Joel and Ellie make their way across the U.S., outrunning zombie hordes while coping with societal collapse, all caused by a nasty mutation in the parasitic Cordyceps fungus,...
Speckle-correlation Technique Recovers Images of Obscured Objects in Real Time
THUWAL, Saudi Arabia, Feb. 2, 2023 — Imaging through a light-scattering medium, such as clouds in the sky or tissues in the body, poses special challenges. The scattered light must be reconstructed, typically by using complex optical elements in an environment that is vulnerable to...
Simple Approach to Laser Color Conversion Uses SRS in Ionic Liquids
UPTON, N.Y., Feb. 1, 2023 — Scientists from Brookhaven National Laboratory showed that ionic liquids provide an efficient means to convert one color of laser light into another. The discovery could lead to a way to create lasers with desired colors for a range of medical,...
Portable Laser-Based Scanning Device Detects Critical Biomarkers
LITTLE ROCK, Ark., July 27, 2022 — Researchers at the University of Arkansas for Medical Sciences (UAMS) reported advances to the previously developed Cytophone device. In the current work, the researchers integrated a miniature multispectral laser diode array, time-color coding, and...
Optical Fiber Sensors Enable New Biomedical Devices
Jun 1, 2022 — The biomedical community recognized the advantages of optical fibers long ago, accepting them even before their adoption for long-haul telecommunications. Early research on the light-guiding properties of fibers in the late 1920s was aimed at...
Safe, Ingestible Fluorescent Silk Tags Authenticate Medications
WEST LAFAYETTE, Ind., April 22, 2022 — To help block the flow of counterfeit medications, researchers at Purdue University and the National Institute of Agricultural Sciences in South Korea developed edible fluorescent tags that can be coded and added to pills or liquid medicine. Each...
Protein-induced Apoptosis in Cancer Cells Protects Healthy Tissue
OKAYAMA, Japan, April 13, 2022 — A research group at Okayama University is working on a way to prevent healthy cells from incurring damage during cancer treatment. The group is developing a light-induced method for triggering cell apoptosis in targeted cells only, using a...
Raman Spectroscopy and Machine Learning Team Up to Predict Immunotherapy Response in Patients
BALTIMORE, Oct. 21, 2021 — Using Raman spectroscopy and machine learning, a team at Johns Hopkins University developed a noninvasive technique to assess how cancer patients will respond to immunotherapy. The researchers used Raman spectroscopy to map the biochemical...
NIR Spectroscopy Could Provide Window into AD Pathology, Therapeutics
BEDFORD, Mass., Sept. 1, 2021 — To detect Alzheimer’s disease (AD) in its early stages, researchers at the VA Bedford and VA Boston Healthcare systems developed a noninvasive optical technique that uses near-infrared spectroscopy to identify changes in the brain by capturing...
PerkinElmer to Acquire BioLegend
WALTHAM, Mass., July 26, 2021 — PerkinElmer (PE) will make the largest transaction in its history. The company has entered into an agreement to acquire BioLegend, a global provider of life science antibodies and reagents, in a deal worth approximately $5.25 billion. The deal is...
Researchers Control Brain States Via Photoswitchable Molecule
BARCELONA, Spain, July 6, 2021 — A team of scientists in Spain has directly photomodulated brain-state transitions in vivo using a photoswitchable molecule that was developed previously by researchers at the Institute for Bioengineering of Catalonia (IBEC). By applying a...
Selecting Color Filter Glass for Life Science Applications
Jul 1, 2021 — Optical filters are critical for selectively passing and blocking specific wavelengths in life science applications ranging from monitoring oxygen and pH levels in blood to fluorescence detection, to the polymerase chain reaction (PCR) tests used to...
Flow Cytometer Operates on Microfluidic Platform, Sorts Cells into Subgroups
EXETER, England, June 28, 2021 — Scientists from the University of Exeter’s Living Systems Institute have developed a flow cytometer that can move individual cells between “virtually” separate microfluidic channels — thereby exposing them to a substance that...
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April 2024
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