Request InfoLeica Microsystems GmbHWETZLAR, Germany, July 26, 2010 — Resolution and contrast are important for fluorescence applications in wide-field microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination. The result is fluorescence images with good contrast, high axial resolution and ultrasharp 2- and 3-D sections of the specimen. Intelligent Structured Illumination Microscopy from Leica Microsystems GmbH uses the proven OptiGrid technique. Working in harmony with the company’s high-quality optics, the aperture diaphragm integrated with the fluorescence light path also...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Sep/Oct 2023 IssueAI-Powered Microscope SoftwareLeica Microsystems’ Aivia 12 software provides AI-powered image analysis. It incorporates the Cellpose deep learning model to tackle dense neuron images, improving soma detection by as much as...Photonics Spectra May 2024 IssueMicrospectrometersThe Lightblades™ Spectrometers from CRAIC Technologies are specifically designed for microspectroscopy in research, industrial, and academic applications. Covering ultraviolet, visible, and...BioPhotonics Mar/Apr 2024 IssueOphthalmic MicroscopeThe Proveo 8 from Leica Microsystems is an ophthalmic microscope with an integrated EnFocus intraoperative OCT. The integration results in a 40% reduction in stack height — from 60 to 36 mm....BioPhotonics Jul/Aug 2023 IssueCooled sCMOS CamerasXimea’s MJ042MR-GP-P11-BSI-UV model was added to its portfolio of scientific cameras. It’s equipped with a Gpixel PulSar sCMOS sensor that is combined with Peltier cooling and USB3...ARTICLESPhotonics Spectra February 2024 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...Photonics Spectra April 2024 IssueUV-LED Photolithography Imparts Micro FeaturesTechnologies like integrated signal distributing, processing, and sensing networks require basic optical elements such as waveguides, splitters, gratings, and optical switches to be miniaturized....Photonics.com 2/5/2024High-Throughput Imaging Reveals Multi-Particle Cellular ActivityA new software program can map the movements of multiple particles within cells simultaneously, providing insight into cellular functions that are difficult — and sometimes impossible —...Photonics Spectra March 2024 IssueQuantum-Inspired Method Reveals Details Hidden in NoiseResearchers at the University of Warsaw's Faculty of Physics with colleagues from Stanford University and Oklahoma State University have introduced a quantum-inspired phase-imaging method based on...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 1/10/2024Single-Objective Light SheetAn overview of the Single-Objective Light Sheet.Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...WEBINARSPhotonics.com 6/5/2013Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 6/6/2024COTS to Custom: Using Microscope Objectives in OEM ProductsDavid Biss of Optikos navigates the trade-offs that must be considered when developing the architecture of a microscope. 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These filters are designed to transmit light with a...Photonics Dictionarywide-field eyepieceAn eyepiece or magnifier capable of covering a field of view that is greater than 50°.VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 8/10/2021Short Introduction of CODIXX, Winner of the AURA foreign trade award 2019 - CODIXXCODIXX is a corporation under German Law, established in September 1998. After a period of research and development CODIXX started the production of a new family of dichroic glass polarizers in 2002....Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 8/24/2022Ramacle® Software Highlight: Fast Mapping - Edinburgh InstrumentsThis Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...PHOTONICS BUYERS' GUIDE CATEGORIESResearch MicroscopesForensic MicroscopesUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...EndoscopesAn endoscope is a medical device used for visualizing and examining the interior of hollow organs, body cavities, or confined spaces within the body. It consists of a flexible or rigid tube equipped...COMPANIESPhotonics Buyers' GuideGlass Fab Inc.A History of Quality Since 1974 Glass Fab Inc. has met customers' stringent specifications by providing fabricated parts made of optical glass, filter glass, fused quartz and fused silica, low...Photonics Buyers' GuideShanghai Optics Inc.ISO 9001 & ISO 13485 certified and D&B DUNS # 113515303 Shanghai Optics is an unparalleled custom system solution provider offering advance precision custom optical design, engineering,...Photonics Buyers' GuideAvantier Inc.Avantier Inc. is an unparalleled leader in providing innovative imaging systems solutions and optical systems solutions. We offer advance precision custom optical design, optical engineering...Photonics Buyers' GuideFresnel Technologies Inc.Fresnel Technologies Inc. is an expert manufacturer of molded plastic optics, including Fresnel lenses and related optical components, as well as infrared transmitting materials and optics made from...