Photonics Dictionary

An aptamer is a short, single-stranded DNA or RNA molecule that can bind to a specific target molecule with high affinity and specificity. Aptamers are often referred to as chemical antibodies due to...

An atomic force microscope (AFM) is a high-resolution imaging and measurement instrument used in nanotechnology, materials science, and biology. It is a type of scanning probe microscope that...

Autofluorescence refers to the natural emission of fluorescence exhibited by certain biological structures or molecules when exposed to light. Unlike fluorescence that results from the application of...

Azadioxatriangulenium is a type of organic compound with a unique triangular molecular structure. It is often abbreviated as ADOTA. This compound belongs to the class of polycyclic aromatic...

A biomarker, short for biological marker, refers to a measurable and quantifiable indicator of a biological condition, process, or response. Biomarkers can be substances or characteristics that are...

A calcium indicator is a molecule that is sensitive to changes in calcium ion (Ca2+) concentrations in biological systems. These indicators are commonly used in various fields, including cell...

Cold atoms refer to atoms that have been cooled to extremely low temperatures, typically in the microkelvin (µK) to nanokelvin (nK) range, close to absolute zero (0 Kelvin or -273.15°C). At...

Cresyl violet, also known as cresyl violet acetate or cresyl echt violet, is a synthetic organic compound belonging to the class of triarylmethane dyes. It is commonly used in histology and...

Differential interference contrast (DIC) microscopy, also known as Nomarski interference contrast microscopy, is an optical imaging technique used in microscopy to enhance the contrast of transparent...

Digital holographic microscopy (DHM) is an advanced imaging technique that combines holography and digital image processing to capture and reconstruct three-dimensional images of objects. This method...

A diode-pumped solid-state laser (DPSSL) is a type of laser system that uses semiconductor diode lasers to pump energy into a solid gain medium, resulting in the generation of coherent light. This...

A fiber laser is a type of laser in which the active gain medium is an optical fiber doped with rare-earth ions such as erbium, ytterbium, or neodymium. Fiber lasers generate coherent light through...

Flow cytometry is a powerful technique used in biology and medicine for the quantitative analysis of the physical and chemical characteristics of cells and particles suspended in a fluid. The method...

Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of...

Fluorescence lifetime imaging (FLIM) is an advanced imaging technique that provides information about the lifetime of fluorescence emissions from fluorophores within a sample. Unlike traditional...

Fluorescence microscopy is a specialized optical imaging technique used in biology, chemistry, and materials science to visualize and study specimens that exhibit fluorescence. Fluorescence is the...

Fluorescent proteins are proteins that exhibit the property of fluorescence, which is the ability to absorb light at a specific wavelength and emit light at a longer wavelength. These proteins are...

A fluorophore is a molecule or a portion of a molecule that has the ability to emit light upon excitation by an external energy source, such as ultraviolet or visible light. The process by which a...

Förster resonance energy transfer (FRET) is a mechanism describing the transfer of energy between two closely spaced fluorescent molecules. This phenomenon is named after the German scientist...

FTIR (Fourier transform infrared) spectrometer is a powerful analytical instrument used to obtain an infrared spectrum of absorption or emission of a solid, liquid, or gas sample. It operates based...

Histochemical staining is a laboratory technique used in biology and medicine to visualize specific chemical components within biological tissues. This technique involves the application of various...

Histology is the branch of biology and medicine that involves the study of the microscopic structure of tissues and organs at the cellular and subcellular levels. It is a field that focuses on the...

Holographic tomography is an advanced imaging technique that combines holography and tomography to provide three-dimensional reconstructions of transparent or weakly scattering objects with high...

Immunohistochemistry (IHC) is a method for detecting antigens or haptens in cells of a tissue section by using labeled antibodies to bind specifically to their antigens. IHC is used for disease...

In vitro is a Latin term that translates to "in glass." In scientific contexts, particularly in biology and medicine, it refers to experiments or procedures conducted outside of a living organism,...

In vivo is a Latin term that translates to "within the living." In scientific contexts, particularly in biology and medicine, it refers to experiments or observations conducted within a living...

An infrared detector is a device that is used to detect and measure infrared radiation, which lies beyond the visible spectrum of light. These detectors are utilized in various applications,...

Intravital microscopy is an imaging technique used to visualize biological processes within living organisms, typically in real-time. Unlike traditional microscopy, which involves the examination of...

Label-free refers to a technique or method that does not require the use of additional labels, tags, or markers to detect or identify specific components or entities. In various scientific and...

Laser-mediated gene transfer refers to a technique in molecular biology and genetic engineering that utilizes lasers to introduce genetic material into cells. This method is a type of gene delivery...

Lensless microscopy, also known as computational or holographic microscopy, is an imaging technique that captures and reconstructs microscopic images without the use of traditional lenses. Instead of...

Metabolic imaging refers to the visualization and quantification of metabolic processes within living organisms, tissues, or cells using various imaging techniques. It provides insights into the...

A metabolite is any small molecule that is a product of metabolism, the chemical processes that occur within living organisms to maintain life. Metabolites can include a wide variety of molecules,...

Micro-optical coherence tomography (micro-OCT) is an imaging technique that is an adaptation of optical coherence tomography (OCT) to achieve high-resolution, cross-sectional imaging of biological...

A microchannel plate (MCP) is a specialized electron multiplier device used in various applications such as particle detection, imaging, spectroscopy, and night vision technology. It consists of a...

Microfluidics is a multidisciplinary field that involves the manipulation and control of very small fluid volumes, typically in the microliter (10-6 liters) to picoliter (10-12 liters) range, within...

MicroRNAs (miRNAs) are a class of small, single-stranded RNA molecules, typically consisting of about 19 to 24 nucleotides, that play important roles in the regulation of gene expression in cells....

Microscopy is a scientific technique that involves the use of microscopes to observe and study objects that are too small to be seen with the naked eye. Microscopes are instruments that magnify and...

Nanoparticle photonic resonator absorption microscopy is a microscopy technique that combines the principles of photonic resonators and nanoparticle imaging to visualize and study biological samples...

Nd:YAG laser refers to a solid-state laser that utilizes neodymium-doped yttrium aluminum garnet (Nd:Y3Al5O12) as the gain medium. This type of laser emits light at a wavelength of 1064 nm in the...

Optical tweezers refer to a scientific instrument that uses the pressure of laser light to trap and manipulate microscopic objects, such as particles or biological cells, in three dimensions. This...

A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light....

Opsins are a group of light-sensitive proteins found primarily in the retinas of vertebrate and invertebrate eyes, as well as in other light-sensitive tissues. These proteins play a crucial role in...

The term perovskite refers to a specific crystal structure commonly found in various materials. Perovskite structures have a cubic arrangement of oxygen ions, forming a framework within which other...

A phage, short for bacteriophage, is a type of virus that infects and replicates within bacteria. Phages are composed of genetic material (either DNA or RNA) surrounded by a protein coat. They are...

Phase contrast microscopy is an optical microscopy technique that enhances the contrast of transparent and colorless specimens, making it possible to visualize fine details and internal structures...

Photobleaching is a phenomenon in which the fluorescence of a fluorophore (a fluorescent molecule or dye) is permanently reduced or eliminated upon prolonged exposure to light. This process occurs...

Photodynamic inactivation (PDI) is a therapeutic approach that utilizes the combination of light, a photosensitizer, and molecular oxygen to induce cell death or inactivate microorganisms. This...

Phototoxicity refers to the harmful effects caused by exposure to light, particularly intense or ultraviolet (UV) light, on living cells or organisms. This phenomenon is often associated with the...

Photovoltaic (PV) refers to a technology that converts sunlight directly into electricity using semiconductors. The term "photovoltaic" is derived from the words "photo," meaning light, and...