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researchers Dictionary Terms

label-free
Label-free refers to a technique or method that does not require the use of additional labels, tags, or markers to detect or identify specific components or entities. In various scientific and technological applications, labeling often involves...
fluorescent protein
Fluorescent proteins are proteins that exhibit the property of fluorescence, which is the ability to absorb light at a...
atomic force microscope
An atomic force microscope (AFM) is a high-resolution imaging and measurement instrument used in nanotechnology, materials...
photobleaching
Photobleaching is a phenomenon in which the fluorescence of a fluorophore (a fluorescent molecule or dye) is permanently...
scanning electron microscope
A scanning electron microscope (SEM) is a powerful imaging instrument used in scientific research, materials...
cold atom
Cold atoms refer to atoms that have been cooled to extremely low temperatures, typically in the microkelvin (µK) to...
quantitative phase imaging
Quantitative phase imaging (QPI) is an advanced imaging technique used in microscopy to measure and analyze the optical...
phase mask
In optics and photolithography, a phase mask refers to a device that modifies the phase of light waves passing through it....
optical coherence tomography imaging system
Optical coherence tomography (OCT) is an imaging technique used in medical diagnostics and biomedical research to obtain...
second-order nonlinear optical properties
Second-order nonlinear optical properties refer to a class of phenomena exhibited by certain materials in response to...
spectroscopy
Spectroscopy is a technique used in the study of interactions between matter and electromagnetic radiation. It involves...
total internal reflection fluorescence
Total internal reflection fluorescence (TIRF) microscopy is an advanced fluorescence microscopy technique that leverages the...
calcium indicator
A calcium indicator is a molecule that is sensitive to changes in calcium ion (Ca2+) concentrations in biological systems....
holographic tomography
Holographic tomography is an advanced imaging technique that combines holography and tomography to provide three-dimensional...
histochemical staining
Histochemical staining is a laboratory technique used in biology and medicine to visualize specific chemical components...
attosecond-pump attosecond-probe spectroscopy
Attosecond-pump attosecond-probe spectroscopy (APAP) is an advanced technique in ultrafast spectroscopy that allows...
phonon
A phonon is a quantum of vibrational energy associated with the periodic motion of atoms or molecules in a crystalline...
volumetric imaging
Volumetric imaging refers to the capture, visualization, and analysis of three-dimensional (3D) information from a volume of...
STED microscopy
STED microscopy, or stimulated emission depletion microscopy, is a superresolution imaging technique in fluorescence...
high-speed motion camera
A high-speed motion camera, also known as a high-speed camera or slow-motion camera, is a specialized imaging device...
scanning electron microscopy
Scanning electron microscopy (SEM) is an advanced imaging technique used in microscopy to obtain high-resolution,...
virtual histology
Virtual histology refers to the use of digital technology and computational methods to simulate or recreate histological...
micro-optical coherence tomography
Micro-optical coherence tomography (micro-OCT) is an imaging technique that is an adaptation of optical coherence tomography...
angular spectrum approach
The angular spectrum approach is a mathematical and computational technique used in the field of optics to analyze and...
monochromator
A monochromator is an optical instrument used to isolate and select a narrow range of wavelengths from a broader spectrum of...
dewetting
Dewetting is a phenomenon in materials science and physics where a thin film or coating spontaneously undergoes a process of...
fluorescence microscopy
Fluorescence microscopy is a specialized optical imaging technique used in biology, chemistry, and materials science to...
entrance slit
The entrance slit, also known simply as the slit, is an essential component in optical instruments such as spectrometers and...
whole slide imaging
Whole slide imaging (WSI), also known as virtual slide microscopy or digital pathology, is a technology that involves the...
vacuum chamber
A vacuum chamber is a sealed enclosure from which air and other gases are removed to create a low-pressure environment,...
structural color
Structural color refers to coloration in materials that is not caused by pigments or dyes but is instead a result of the...
ratiometry
Ratiometry is a technique used in various scientific fields, particularly in analytical chemistry and biochemistry, to...
single-molecule FRET
Single-molecule Förster resonance energy transfer (smFRET) is a specialized technique in biophysics and molecular...
attosecond photonics sources
Attosecond photonics sources refer to devices or systems that generate extremely short pulses of light on the order of...
lock-in amplifier
A lock-in amplifier is a specialized electronic instrument used to extract and measure small signals embedded in noise or...
lensless microscopy
Lensless microscopy, also known as computational or holographic microscopy, is an imaging technique that captures and...
superresolution
Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by...
three-photon microscopy
Three-photon microscopy is an advanced imaging technique that belongs to the family of multi-photon microscopy methods. It...
rare earth dopants
Rare earth dopants refer to elements from the lanthanide series, also known as rare earth elements, that are intentionally...
optical testing instrument
An optical testing instrument is a device or system used to evaluate and measure the performance, quality, and...
structured illumination microscopy
Structured illumination microscopy (SIM) is an advanced optical imaging technique used in microscopy to enhance the...
Kerr effect
The Kerr effect, named after the physicist John Kerr who first observed it in 1875, is a nonlinear optical phenomenon where...
metalens
A metalens, short for "metasurface lens," is a type of optical lens that uses nanostructured materials to manipulate light...
phase screen
A phase screen, in the context of optics and wave optics, refers to a surface or medium that introduces a phase delay to an...
time-lapse optical coherence tomography
Time-lapse optical coherence tomography (OCT) refers to a medical imaging technique that captures a series of sequential OCT...
digital holographic microscopy
Digital holographic microscopy (DHM) is an advanced imaging technique that combines holography and digital image processing...
second-harmonic generation
Second-harmonic generation (SHG) is a nonlinear optical process that occurs when two photons with the same frequency combine...
fiber optic spectrometer
A fiber optic spectrometer is a device used for measuring the spectral content of light. It utilizes optical fibers to...
metabolite
A metabolite is any small molecule that is a product of metabolism, the chemical processes that occur within living...
metabolic imaging
Metabolic imaging refers to the visualization and quantification of metabolic processes within living organisms, tissues, or...
magnon
A magnon is a quasiparticle representing a quantized spin wave in a magnetic material. In other words, it is a collective...
tip-enhanced Raman scattering
Tip-enhanced Raman scattering (TERS) is a powerful technique that combines Raman spectroscopy with the enhanced spatial...
free-electron laser
A free-electron laser (FEL) is a type of laser that generates coherent, high-intensity electromagnetic radiation by using a...
histology
Histology is the branch of biology and medicine that involves the study of the microscopic structure of tissues and organs...
reticle
A reticle, also known as a reticule or graticule, is a pattern or set of markings placed in the focal plane of an optical...
neuromorphic
Neuromorphic refers to the design and development of computing systems or devices that are inspired by the structure and...
in vitro
In vitro is a Latin term that translates to "in glass." In scientific contexts, particularly in biology and medicine, it...
surface-enhanced Raman scattering
Surface-enhanced Raman scattering (SERS) is a powerful analytical technique that enhances the Raman scattering signal of...
scientific CMOS camera
A scientific CMOS (complementary metal-oxide-semiconductor) camera is a type of digital camera specifically designed for...
spectral flow cytometry
Spectral flow cytometry is an advanced flow cytometry technique that expands the capabilities of traditional flow cytometry...
solar simulator
A solar simulator is a device used to replicate the spectrum and intensity of sunlight in a controlled environment for...
spectral repeatability
Spectral repeatability refers to the consistency and reproducibility of spectral measurements across multiple trials or...
phototoxicity
Phototoxicity refers to the harmful effects caused by exposure to light, particularly intense or ultraviolet (UV) light, on...
ospin
Opsins are a group of light-sensitive proteins found primarily in the retinas of vertebrate and invertebrate eyes, as well...
single molecule localization microscopy
Single molecule localization microscopy (SMLM) is a group of super-resolution microscopy techniques that surpass the...
nanoparticle photonic resonator absorption microscopy
Nanoparticle photonic resonator absorption microscopy is a microscopy technique that combines the principles of photonic...
intravital microscopy
Intravital microscopy is an imaging technique used to visualize biological processes within living organisms, typically in...
diffuse reflectance spectroscopy
Diffuse reflectance spectroscopy (DRS) is a nondestructive analytical technique used to investigate the optical properties...
microscopy
Microscopy is a scientific technique that involves the use of microscopes to observe and study objects that are too small to...
nitrogen vacancy
A nitrogen vacancy (NV) refers to a specific type of defect or impurity in a crystal lattice where a nitrogen atom replaces...
molecular motor
A molecular motor refers to a nano-sized device composed of organic molecules or other small-scale components that can...
topological photonics
Topological photonics is a branch of physics and optics that explores the application of topological concepts to the...
metamaterial
Metamaterials are artificial materials engineered to have properties not found in naturally occurring substances. These...
spectral signature
A spectral signature, in the context of remote sensing and spectroscopy, refers to the unique pattern or characteristic...
modulation transfer function analysis/measurement equipment
MTF analysis/measurement equipment refers to instruments and tools used to measure and analyze the modulation transfer...
plasmonics
Plasmonics is a field of science and technology that focuses on the interaction between electromagnetic radiation and free...
optical tweezers
Optical tweezers refer to a scientific instrument that uses the pressure of laser light to trap and manipulate microscopic...
optogenetics
A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue,...
in vivo
In vivo is a Latin term that translates to "within the living." In scientific contexts, particularly in biology and...
flow chemistry
Flow chemistry, also known as continuous-flow chemistry, is a chemical manufacturing process where reactions take place in a...
stochastic optical reconstruction microscopy
Stochastic optical reconstruction microscopy (STORM) is a superresolution microscopy technique that enables imaging of...
Förster resonance energy transfer
Förster resonance energy transfer (FRET) is a mechanism describing the transfer of energy between two closely spaced...
laser damage threshold
The laser damage threshold refers to the maximum level of laser intensity that a material can withstand without experiencing...
ultrafast pulsed laser
An ultrafast pulsed laser is a type of laser that emits extremely short pulses of light with durations typically on the...
meta-optics
Meta-optics, also known as metasurface optics or flat optics, is a branch of optics that involves the design, fabrication,...
frequency comb
A frequency comb is a precise and regular series of equally spaced spectral lines, or frequencies, that are generated with...
Photoelastic equipment and supplies
Photoelastic equipment and supplies refer to instruments and materials used in photoelasticity, a technique used to analyze...
phase contrast microscopy
Phase contrast microscopy is an optical microscopy technique that enhances the contrast of transparent and colorless...
CubeSat
A CubeSat is a type of miniaturized satellite characterized by its standardized size and modular design. CubeSats are...

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