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BioPhotonics: June 2008

BioPhotonics
 June 2008


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FEATURES
High-Speed Imaging for DNA Sequencing The key to personalized medicine is understanding the role that an individual’s genes play in his or her health. To reap the benefits of personalized medicine, the billions of nucleotide bases that comprise an individual’s genome must be sequenced — and done so at an affordable price. This means lowering the price tag from the $3 billion spent on the Human Genome Project to $100,000 and,...
Getting a Better View from the Inside According to modern medicine, there is a grain of truth in the old adage: The way to a man’s heart is through his stomach. Dr. Michael B. Wallace, a gastroenterologist with the Mayo Clinic in...
Polarized Crystals Enable Malaria Diagnosis According to the 2005 World Malaria Report by the World Health Organization and UNICEF, as many as 500 million malaria cases are recorded each year, resulting in at least 1 million deaths. Although a...
Quantum Dots Move Beyond Fluorescence Imaging Quantum dots are transforming life sciences imaging because of their extraordinary photostability, brightness, broad excitation, narrow emission, long fluorescence lifetimes and multiplexing...
A Bridging Method Expands the Quantum Efficiency of Sensors The demand for cost-effective, high-performance imaging detectors is prevalent within the scientific research community. CCD sensors are arrays of photosensitive pixels that are covered by...
POST SCRIPTS
Don’t move: Improving immobilization for 3-D imaging and laser surgery Researchers often turn to the small semitransparent organism known as C. elegans for investigations of disease models, including, for example, Parkinson’s and Alzheimer’s diseases and muscular dystrophy. However, the traditional approaches to using C. elegans as a model system have proved ill-suited to high-throughput investigations. In a PNAS paper published last year, Mehmet Fatih Yanik, a...
AS WE GO TO PRESS
Medical imaging could be a cell phone call away Approximately three-quarters of people worldwide have no access to medical imaging, according to the World Health Organization, based in Geneva. It is estimated that medical imaging would benefit the...
PCR in just minutes, including sample preparation Because the polymerase chain reaction (PCR) can make exponentially more nucleic acids from DNA or RNA extracted from cells and tissues, the technique has revolutionized medicine, forensics and basic...
BREAKTHROUGHMEDIA
Optical components The “2008 Best Sellers Catalog” from Edmund Optics Inc. features the company’s newest and most popular optical components, as selected by its customers and engineering staff. The 263-page document...
Luminescence The 276-page volume Luminescence: From Theory to Applications is targeted to chemists, electrochemists, materials scientists, lamp and lighting manufacturers, and those working in the optical...
Vibration isolation The “2008 General Catalog” from Technical Manufacturing Corp. presents the company’s precision vibration isolation systems, including its recent offerings in piezoelectric transducer (PZT)...
Antibodies resource A 45-page brochure titled “Antibodies 2008-2009” from AnaSpec Inc. details the company’s custom services in rabbit and chicken antibody production, antibody purification and labeling, and...
Objectives Carl Zeiss MicroImaging Inc. has launched its online Objectives Data Base to assist researchers in selecting the appropriate objective for applications in microscopy. It recommends objectives based...
Biomedical surfaces Part of the “Engineering in Medicine & Biology” series, Biomedical Surfaces addresses artificial implant surfaces, including the interactions between biomaterials and biological media. The...
PRODUCTS
488-nm laser systems Toptica Photonics AG has expanded its iBeam and iPulse diode laser systems with the addition of 488-nm single-mode diodes, which have applications in biophotonics and bioanalytics, particularly in...
Toptica Photonics AG
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Angiogenesis slide The μ-Slide Angiogenesis carrier for angiogenesis assays is part of the μ-Slide family of flow-through devices for the functional analysis of living cells, which consists of slides for...
ibidi GmbH
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Force spectroscope JPK Instruments AG has introduced the ForceRobot system to automate force spectroscopy, a single-molecule technique that allows the real-time study of molecular interactions on the nanoscale. Mounted...
JPK Instruments AG
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Automated cell counter Nexcelom Bioscience LLC has introduced Cellometer Vision, a cell counter with multimode imaging analysis. The device improves throughput by automating tedious manual counting procedures. After a...
Nexcelom Bioscience
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CW laser Cobolt AB’s 532-nm single-mode solid-state laser now is available with up to 300 mW of CW output power. The Cobolt Samba is a true single-longitudinal-mode laser with a measured linewidth of <1...
Cobolt AB
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FT spectrometer The Arcspectro HT-2D from Arcoptix SA is a stationary Fourier transform (FT) spectrometer. The 400- to 1100-nm spectrometer exhibits 1.7-, 5- and 10-nm FWHM spectral resolution at 400, 700 and 1000...
ARCoptix SA
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Mass spectrometer Bruker Daltonics Inc. has released the micrOTOF-Q II, a quadrupole time-of-flight mass spectrometer that offers the SmartFormula 3-D method for the unambiguous sum formulation determination of small...
Bruker Daltonics Inc.
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Microscope lighting Carl Zeiss MicroImaging GmbH has introduced the C LED stand for its Stemi DV4 stereomicroscope, which contains LEDs that illuminate specimens more brightly and homogeneously than halogen lamps do,...
Carl Zeiss Spectroscopy GmbH
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Microscope objectives Edmund Optics Inc. has introduced a family of infinity-corrected long-working-distance objectives. The eight lenses have a plan apochromat design that enables resolutions from 5 to 0.34 μm. They...
Edmund Optics Inc.
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Antifog insert Laservision GmbH & Co. KG has introduced an antifog insert for laser safety goggles that provides a permanent clear view and ensures a visibly safe and secure feeling for users. The insert is a...
laservision GmbH
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Beam shaper Refractive Focal-πShaper systems from MolTech GmbH convert a Gaussian laser beam into flattop, “donut,” “reverse Gauss,” “trident” or rooflike intensity profiles near the focal plane of a...
MolTech GmbH
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Color cameras Mightex Systems has unveiled USB 2.0, 8-bit, 2048 × 1536-pixel color CMOS cameras with 32-MB onboard memory. They can be used for digital microscopy and medical imaging, and they operate at up to 8...
Mightex Systems
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Interferometer Interferometric Optics N-slit laser interferometer has applications in microscopy and microdensitometry, and in the assessment of transmission gratings. Based on multiple-prism beam expansion and on...
Interferometric Optics
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Modular spectrometer Ocean Optics Jaz family of stackable modules work together or separately. One module is a Czerny-Turner spectrometer with a 200- to 1100-nm linear CCD array and 14 grating options as well as...
Ocean Optics Inc.
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Intense light source Optical Building Blocks Corp. has introduced the KiloArc light source, which delivers more than 100 W in less than an 8-mm-diameter area. In one 489 × 375 × 329-mm package, the light source includes...
Optical Building Blocks
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Photomultiplier tube Vertilon Corp. has unveiled the SIB064 sensor interface board for the Hamamatsu H8500D 64-anode photomultiplier tube (PMT). For typical applications such as PET, single-photon-emission CT and...
Vertilon Corp.
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Spectrophotometer Thermo Fisher Scientific Inc. has introduced a sample position illuminator that now is standard with its NanoDrop 8000 spectrophotometer. It lights wells from underneath the plate to help the user...
Thermo Scientific - CIDTEC, CIDTEC Cameras & Imagers
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UV flashlight Spectronics Corp. has unveiled the Spectroline Optimax 365, a cordless LED flashlight for photoactivation and UVA dosing. It emits 365-nm light at intensities up to 50 mW/cm2 at a distance of 15 cm....
Spectronics Corp., Spectroline
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In vivo imaging Available from Cambridge Research & Instrumentation Inc., the DyCE dynamic contrast enhancement software is designed for use with the Maestro multispectral in vivo molecular imaging system for...
PerkinElmer
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TCSPC microscopy Horiba Jobin Yvon Inc. has introduced the DynaMic system designed to apply time-resolved fluorescence spectroscopy on the micron scale. The filter-based confocal instrument adapts time-correlated...
HORIBA Scientific
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Bioluminescence imaging The Luminoview LV200 bioluminescence microscope from Olympus Life Science Europa GmbH performs imaging for small organisms and slice cultures as well as at the single-cell scale. It features full...
Olympus Europa SE & Co. KG, Medical Systems & Micro-Imaging Solutions Group
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OEM laser Impex High Tech GmbH has unveiled the 1064-Q Laser OEM, a 1064-nm pulsed laser that operates in a longitudinal single-mode, passively Q-switched regime and generates more than 5-kW peak power in...
Imperx Inc.
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Spectrometers The i-trometer series spectrometers employ a high-UV/VIS/NIR response, a wide dynamic range and a back-thinned CCD array. The miniature devices from B&W Tek Inc. offer a high quantum efficiency...
B&W Tek
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Microkeratome Moria Inc. offers the One Use-Plus SBK microkeratome, an instrument used in laser vision correction surgery, particularly in SBK (thin-flap lasik). According to the company, the device compared...
Moria Inc.
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Microplate sealer Porvair Sciences Ltd. has introduced the TriSeal automated plate sealer for fast and accurate microplate sealing on any SBS-standard microplate up to a maximum height of 45 mm. Using a turntable...
Porvair Sciences Ltd.
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Microscope photometer Craic Technologies Inc. has unveiled the QDI MP1 microscope photometer, an all-solid-state system designed for photometry of microscopic samples in fields including cytophotometry and mineralogy. The...
CRAIC Technologies
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Imaging software Carestream Molecular Imaging, a division of Carestream Health Inc., has introduced the Kodak Molecular Imaging Software 5.0. Designed to perform digital capture and analysis for a variety of...
Carestream Health, Molecular Imaging
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Nanopositioner The Tritor line of positioners manufactured by piezosystem jena GmbH has been expanded with the addition of the Tritor 50 Cap nanopositioner. Providing travel of 50 μm, the 55 × 42 × 35-mm...
piezosystem jena GmbH
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Unbiased stereology The Stereo Investigator 8.0 system for unbiased stereology offers enhanced support for confocal, multichannel fluorescence and bright-field microscopy. Its work flow technology and probe interfaces...
MBF Bioscience
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Calcium indicator The Fluo-3 high-affinity fluorescent calcium indicator, available from AnaSpec Inc., absorbs at approximately 506 nm and emits at 526 nm when bound to calcium. Its higher dissociation constant and...
AnaSpec
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