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BioPhotonics
June 2008
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FEATURES
High-Speed Imaging for DNA Sequencing
The key to personalized medicine is understanding the role that an individual’s genes play in his or her health. To reap the benefits of personalized medicine, the billions of nucleotide bases that comprise an individual’s genome must be sequenced — and done so at an affordable price. This means lowering the price tag from the $3 billion spent on the Human Genome Project to $100,000 and,...
Getting a Better View from the Inside
According to modern medicine, there is a grain of truth in the old adage: The way to a man’s heart is through his stomach. Dr. Michael B. Wallace, a gastroenterologist with the Mayo Clinic in...
Polarized Crystals Enable Malaria Diagnosis
According to the 2005 World Malaria Report by the World Health Organization and UNICEF, as many as 500 million malaria cases are recorded each year, resulting in at least 1 million deaths. Although a...
Quantum Dots Move Beyond Fluorescence Imaging
Quantum dots are transforming life sciences imaging because of their extraordinary photostability, brightness, broad excitation, narrow emission, long fluorescence lifetimes and multiplexing...
A Bridging Method Expands the Quantum Efficiency of Sensors
The demand for cost-effective, high-performance imaging detectors is prevalent within the scientific research community. CCD sensors are arrays of photosensitive pixels that are covered by...
AS WE GO TO PRESS
Medical imaging could be a cell phone call away
Approximately three-quarters of people worldwide have no access to medical imaging, according to the World Health Organization, based in Geneva. It is estimated that medical imaging would benefit the...
PCR in just minutes, including sample preparation
Because the polymerase chain reaction (PCR) can make exponentially more nucleic acids from DNA or RNA extracted from cells and tissues, the technique has revolutionized medicine, forensics and basic...
BREAKTHROUGHMEDIA
Optical components
The “2008 Best Sellers Catalog” from Edmund Optics Inc. features the company’s newest and most popular optical components, as selected by its customers and engineering staff. The 263-page document...
Luminescence
The 276-page volume Luminescence: From Theory to Applications is targeted to chemists, electrochemists, materials scientists, lamp and lighting manufacturers, and those working in the optical...
Vibration isolation
The “2008 General Catalog” from Technical Manufacturing Corp. presents the company’s precision vibration isolation systems, including its recent offerings in piezoelectric transducer (PZT)...
Antibodies resource
A 45-page brochure titled “Antibodies 2008-2009” from AnaSpec Inc. details the company’s custom services in rabbit and chicken antibody production, antibody purification and labeling, and...
Objectives
Carl Zeiss MicroImaging Inc. has launched its online Objectives Data Base to assist researchers in selecting the appropriate objective for applications in microscopy. It recommends objectives based...
Biomedical surfaces
Part of the “Engineering in Medicine & Biology” series, Biomedical Surfaces addresses artificial implant surfaces, including the interactions between biomaterials and biological media. The...
POST SCRIPTS
Don’t move: Improving immobilization for 3-D imaging and laser surgery
Researchers often turn to the small semitransparent organism known as C. elegans for investigations of disease models, including, for example, Parkinson’s and Alzheimer’s diseases and muscular dystrophy. However, the traditional approaches to using C. elegans as a model system have proved ill-suited to high-throughput investigations. In a PNAS paper published last year, Mehmet Fatih Yanik, a...
PRODUCTS
488-nm laser systems
Toptica Photonics AG has expanded its iBeam and iPulse diode laser systems with the addition of 488-nm single-mode diodes, which have applications in biophotonics and bioanalytics, particularly in flow cytometry, confocal microscopy, and high-throughput and high-content screening. Previously, this wavelength was obtained only by argon gas lasers and frequency-doubled solid-state lasers. The iBeam...
Toptica Photonics AG
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Angiogenesis slide
The μ-Slide Angiogenesis carrier for angiogenesis assays is part of the μ-Slide family of flow-through devices for the functional analysis of living cells, which consists of slides for...
ibidi GmbH
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Force spectroscope
JPK Instruments AG has introduced the ForceRobot system to automate force spectroscopy, a single-molecule technique that allows the real-time study of molecular interactions on the nanoscale. Mounted...
Bruker Nano GmbH, JPK BioAFM
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Automated cell counter
Nexcelom Bioscience LLC has introduced Cellometer Vision, a cell counter with multimode imaging analysis. The device improves throughput by automating tedious manual counting procedures. After a...
Nexcelom Bioscience
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CW laser
Cobolt AB’s 532-nm single-mode solid-state laser now is available with up to 300 mW of CW output power. The Cobolt Samba is a true single-longitudinal-mode laser with a measured linewidth of <1...
Cobolt AB
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FT spectrometer
The Arcspectro HT-2D from Arcoptix SA is a stationary Fourier transform (FT) spectrometer. The 400- to 1100-nm spectrometer exhibits 1.7-, 5- and 10-nm FWHM spectral resolution at 400, 700 and 1000...
ARCoptix SA
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Mass spectrometer
Bruker Daltonics Inc. has released the micrOTOF-Q II, a quadrupole time-of-flight mass spectrometer that offers the SmartFormula 3-D method for the unambiguous sum formulation determination of small...
Bruker Daltonics Inc.
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Microscope lighting
Carl Zeiss MicroImaging GmbH has introduced the C LED stand for its Stemi DV4 stereomicroscope, which contains LEDs that illuminate specimens more brightly and homogeneously than halogen lamps do,...
Carl Zeiss Spectroscopy GmbH
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Microscope objectives
Edmund Optics Inc. has introduced a family of infinity-corrected long-working-distance objectives. The eight lenses have a plan apochromat design that enables resolutions from 5 to 0.34 μm. They...
Edmund Optics Inc.
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Antifog insert
Laservision GmbH & Co. KG has introduced an antifog insert for laser safety goggles that provides a permanent clear view and ensures a visibly safe and secure feeling for users. The insert is a...
LASERVISION GmbH & Co. KG
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Beam shaper
Refractive Focal-πShaper systems from MolTech GmbH convert a Gaussian laser beam into flattop, “donut,” “reverse Gauss,” “trident” or rooflike intensity profiles near the focal plane of a...
MolTech GmbH
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Color cameras
Mightex Systems has unveiled USB 2.0, 8-bit, 2048 × 1536-pixel color CMOS cameras with 32-MB onboard memory. They can be used for digital microscopy and medical imaging, and they operate at up to 8...
Mightex Systems
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Interferometer
Interferometric Optics N-slit laser interferometer has applications in microscopy and microdensitometry, and in the assessment of transmission gratings. Based on multiple-prism beam expansion and on...
Interferometric Optics
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Modular spectrometer
Ocean Optics Jaz family of stackable modules work together or separately. One module is a Czerny-Turner spectrometer with a 200- to 1100-nm linear CCD array and 14 grating options as well as...
Ocean Insight
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Photomultiplier tube
Vertilon Corp. has unveiled the SIB064 sensor interface board for the Hamamatsu H8500D 64-anode photomultiplier tube (PMT). For typical applications such as PET, single-photon-emission CT and...
Vertilon Corp.
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Spectrophotometer
Thermo Fisher Scientific Inc. has introduced a sample position illuminator that now is standard with its NanoDrop 8000 spectrophotometer. It lights wells from underneath the plate to help the user...
Thermo Scientific - CIDTEC, Cameras & Imagers
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UV flashlight
Spectronics Corp. has unveiled the Spectroline Optimax 365, a cordless LED flashlight for photoactivation and UVA dosing. It emits 365-nm light at intensities up to 50 mW/cm2 at a distance of 15 cm....
Spectronics Corp., Spectroline
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In vivo imaging
Available from Cambridge Research & Instrumentation Inc., the DyCE dynamic contrast enhancement software is designed for use with the Maestro multispectral in vivo molecular imaging system for...
PerkinElmer
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TCSPC microscopy
Horiba Jobin Yvon Inc. has introduced the DynaMic system designed to apply time-resolved fluorescence spectroscopy on the micron scale. The filter-based confocal instrument adapts time-correlated...
HORIBA Scientific
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Bioluminescence imaging
The Luminoview LV200 bioluminescence microscope from Olympus Life Science Europa GmbH performs imaging for small organisms and slice cultures as well as at the single-cell scale. It features full...
Olympus Europa SE & Co. KG
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OEM laser
Impex High Tech GmbH has unveiled the 1064-Q Laser OEM, a 1064-nm pulsed laser that operates in a longitudinal single-mode, passively Q-switched regime and generates more than 5-kW peak power in...
Imperx Inc.
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Spectrometers
The i-trometer series spectrometers employ a high-UV/VIS/NIR response, a wide dynamic range and a back-thinned CCD array. The miniature devices from B&W Tek Inc. offer a high quantum efficiency...
B&W Tek LLC
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Microkeratome
Moria Inc. offers the One Use-Plus SBK microkeratome, an instrument used in laser vision correction surgery, particularly in SBK (thin-flap lasik). According to the company, the device compared...
Moria Inc.
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Microplate sealer
Porvair Sciences Ltd. has introduced the TriSeal automated plate sealer for fast and accurate microplate sealing on any SBS-standard microplate up to a maximum height of 45 mm. Using a turntable...
Porvair Sciences Ltd.
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Microscope photometer
Craic Technologies Inc. has unveiled the QDI MP1 microscope photometer, an all-solid-state system designed for photometry of microscopic samples in fields including cytophotometry and mineralogy. The...
CRAIC Technologies
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Nanopositioner
The Tritor line of positioners manufactured by piezosystem jena GmbH has been expanded with the addition of the Tritor 50 Cap nanopositioner. Providing travel of 50 μm, the 55 × 42 × 35-mm...
piezosystem jena GmbH
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Unbiased stereology
The Stereo Investigator 8.0 system for unbiased stereology offers enhanced support for confocal, multichannel fluorescence and bright-field microscopy. Its work flow technology and probe interfaces...
MBF Bioscience
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