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BioPhotonics: October 2006

BioPhotonics
 October 2006


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FEATURES
Lasers Stimulate New Techniques in Nerve Studies Neural tissue stimulation is used in research and clinical applications. Neuroscientists use nerve stimulation to answer fundamental questions about the function of the nervous system and to research diseases such as Parkinson’s and Alzheimer’s as well as biological processes such as nerve regeneration. Clinically, neural tissue stimulation is used for applications including pain and...
In Vivo Experimental Imaging of Complex Disease Processes In vivo studies are the only way to accurately assess the interactions of multiple cell types in the context of complex anatomical features. Cancer and inflammatory disease, for example, represent...
Confocal Raman Microscopy: A Clinical and Biological Tool Scientists in the fields of biology and biochemistry are familiar with some of the more common forms of spectroscopic analysis, such as absorption and emission spectroscopy. The former measures the...
RAPIDSCAN
Atomic force fluorescence microscopy reveals elasticity of blood clot fibers Blood clots are important for stopping the flow of blood and sealing wounds after an injury. However, if they block arteries, they can cause conditions such as heart attacks and strokes. Although...
Flagella nanotubes visualized microscopically Scientists envision nanotubes as antibiotics, reaction media, catalysts, drug delivery devices and microcircuit conductors. Although carbon nanotubes already exist, they cannot be genetically...
MRI measures neural correlates of the alerting effect of light Decreased alertness causes workers to make more errors, increasing costs and resulting in additional damage. If a doctor or a fireman makes a mistake, for example, it could end someone’s...
Optofluidic microscope enables lensless imaging of microorganisms In biological research or clinical applications, optical imaging typically is performed using large microscope systems with expensive optics. Now researchers at California Institute of Technology in...
Near-IR light measures nutrient content in manure Manure contributes to the fertility of soil by adding nutrients such as nitrogen, phosphorus and ammonia. However, not only is it possible not to get enough nutrients, but also crops can become...
Robot assists laparoscopic surgery An estimated one out of nine American women will undergo a hysterectomy, a surgery to remove all or some of the uterus, at some point in their lifetime. Ten percent of these women will develop...
Syncroscopy Syncroscopy of Cambridge, UK, has agreed to allow Leica Microsystems of Wetzlar, Germany, to integrate its Auto-Montage Pro software with Leica’s Application Suite software. The resulting...
Prodesse Inc. Prodesse Inc. of Waukesha, Wis., and Invitrogen Corp. of Carlsbad, Calif., have signed a licensing agreement for diagnostic assays that incorporate the latter company’s Lux technology, reagents...
austriamicrosystems AG A long-term partnership between austriamicrosystems AG of Unterpremstätten, Austria, and Siemens Medical Solutions USA Inc. of Malvern, Pa., has resulted in an agreement in which the Austrian...
PerkinElmer Inc. PerkinElmer Inc. of Boston has attained Raman spectroscopy platforms through the acquisition of Avalon Instruments of Belfast, UK. The technology will be made available to photonics markets such as...
Hyphenated Systems Hyphenated Systems of Burlingame and Stanford Microfluidics Laboratory, both in California, have announced a joint development project for the study of structure and flow in microfluidic devices. The...
Autism Consortium The Autism Consortium has selected a microarray technology developed by Affymetrix Inc., of Santa Clara, Calif., for a comprehensive study on genes associated with autism. The technology is a result...
National Human Genome Research Institute The National Human Genome Research Institute, based in Bethesda, Md., has announced that it will establish a Center of Excellence in Genomic Science at California Institute of Technology in Pasadena...
Li-Cor Biosciences Li-Cor Biosciences of Lincoln, Neb., has offered $1.75 million in genomics education matching funds to high schools, colleges and universities so that they can acquire the company’s DNA...
Omega Optical Inc. Omega Optical Inc. of Brattleboro, Vt., has announced that its filter sets for imaging quantum dot nanocrystals will be available for purchase from Fisher Scientific of Hampton, N.H. The sets can be...
Centre for Integrated Photonics The Centre for Integrated Photonics of Ipswich, UK, has won a £215,000 contract to develop a portable device that will enable DNA fingerprinting at crime scenes, before contamination of...
Evotec AG Evotec AG of Hamburg, Germany, has sold the core of its single-molecule detection technology and has transferred or licensed the corresponding intellectual property portfolio to Olympus Corp. of...
Olympus America Inc. Olympus America Inc. of Center Valley, Pa., obtained privately held Bacus Laboratories Inc. of Lombard, Ill. Olympus America’s microscope hardware and Bacus’ virtual microscope slide...
Aperio Technologies Inc. Aperio Technologies Inc. has expanded its European operations by opening a new, larger center in Bristol, UK, which will house sales, marketing and business development personnel. The move will...
The Infotonics Technology Center Inc. The Infotonics Technology Center Inc. of Canandaigua, N.Y., and Mediscience Technology Corp. of Cherry Hill, N.J., have announced that they will join forces to develop an optical biopsy pill. A New...
AS WE GO TO PRESS
Critter’s colon takes top photo prize Paul L. Appleton dared to go where few have gone before: into a mouse’s colon. And for his efforts, the researcher from the University of Dundee in the UK won the top prize at Nikon’s annual Small World photography contest. Appleton captured the pebbly, cobalt blue texture of the cell nuclei of a mouse colon (right) as seen with two-photon fluorescence microscopy. The digital image,...
Researchers use computer-imaging technique to study Alzheimer’s A new computer-assisted analysis technique may better identify cellular damage associated with the onset of Alzheimer’s disease. Researchers led by Min-Ying Su of the University of...
Putting a superlens to work Researchers from Max Planck Institute for Biochemistry in Martinsried, Germany, and the University of Texas at Austin have imaged objects far smaller than the illumination wavelength by combining...
Real-time measurement of energy expenditure in the heart Scientists at the University of Bristol, the University of Cambridge and Imperial College London, all in the UK, have made real-time measurements of ATP levels in heart cells using luciferase. Their...
Computer systems could accelerate breast cancer detection Computer-aided detection could nearly halve the time needed to perform breast cancer screens, enabling women to have more personal consultations and to undergo more routine x-rays. Current procedures...
BREAKTHROUGHMEDIA
Flow cytometry The “Flow Cytometry Catalog 2006” from Invitrogen Corp. features Caltag primary antibody conjugates, Molecular Probes labeling and detection technologies, Dynal magnetic bead-based...
Dendrimers Using an interdisciplinary approach with emphasis on biological applications, Dendrimers in Medicine and Biotechnology: New Molecular Tools discusses the relationship between the dendrimer molecular...
Optical filters A manufacturer of optical filters for the biotechnology and analytical instrumentation market, Semrock Inc. has issued its 2006-2007 catalog. The 48-page, full-color publication presents filtersfor...
Molecular analysis Released by Bruker Daltonics, application note FTMS-35 — titled “apex-Qe: A Powerful Platform for Molecular Formula Determination” — provides datathat illustrates the...
Nanotech regulations The 204-page Nanotechnology Regulation and Policy Worldwide describes legal and policy initiatives that are designed toeither encourage or restrict nanotechnology research and applications. Targeted...
Drug discovery, HTS Issue 16 of “Cell Notes,” a serial publication of Promega Corp., focuses on drug discovery and high-throughput screening, emphasizing the use of in vitro assays to understand in vivo...
Reagents, probes The 2006/2007 catalog released by Dojindo Molecular Technologies Inc. presents labeling reagents for protein analysis, including the HiLyte Fluor 750 labeling kits, as well as cell viability and...
Fluorescent dyes The downloadable “Martek Fluorescent Products 2006-2007 Catalog” from Martek Biosciences Corp. details conjugates, assay formats, optical properties and laser excitation lines of the dye...
Commercial optics The Fall 2006 catalog of Anchor Optics, a division of Edmund Optics, features an expanded line of commercial-grade optics suitable for production, prototyping and OEM use. The 192-page, full-color...
Biomedical engineering Stories of patients whose lives have been saved or improved by biomedical devices such as the cardiac defibrillator and the insulin pump are described in Medicine by Design: The Practice and Promise...
POST SCRIPTS
Squids may communicate incognito The squid’s skin is made of a layer of superficially located pigmented chromatophores and underlying iridophores (reflector cells). During camouflage, the squid can cover reflector cells with chromatophores in a fraction of a second. These facing images show the same irid?ophore splotch with yellow chromatophores retracted (left) and expanded to cover polarized iridophores (bottom right)....
PRODUCTS
Microscopy filter sets The QuantaMax fluorescence filter sets from Omega Optical Inc. have “energetic process” coatings that are durable, spectrally stable and insensitive to moisture. Offering zero pixel shift, they feature a multisubstrate air-spaced assembly that provides protection from handling and mechanical abrasion during laboratory use. The high-throughput sets are designed with deep blocking to...
Omega Optical LLC
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Holographic optical trapping Arryx Inc., a subsidiary of Haemonetics Corp., and Boulder Nonlinear Systems Inc. have introduced the Hotkit holographic optical trapping kit, available in three models. When combined with a suitable...
Boulder Nonlinear Systems Inc.
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Fluorescence modeling Lambda Research Corp. has announced the fluorescence-simulating capability available in TracePro Expert, a software tool for modeling and analyzing the propagation of light in optomechanical systems....
Lambda Research Corporation
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Dual AC imaging Asylum Research has introduced the Dual AC imaging mode for its MFP-3D atomic force microscope. The device goes beyond conventional phase imaging in measuring the mechanical and chemical properties...
Oxford Instruments Asylum Research
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Mass spectrometer Available from Bruker Daltonics, an operating company of Bruker BioSciences Corp., the autoflex III smartbeam vertical Maldi-Tof or Tof/Tof mass spectrometer is suitable for expression and...
Bruker Daltonics Inc.
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Raman workstation The Raman Workstation manufactured by McPherson Inc. is a total spectroscopy system that includes a solid-state laser, specialty filters, a sample chamber with laser focusing and signal collection...
McPHERSON
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Spectrometer Jasco Inc. has released the V-630Bio model UV, VIS and near-IR spectrophotometer. It comprises an intelligent remote module that contains a color LCD touch screen and a micro cell holder. Features...
JASCO Inc.
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Optical enclosures Kinetic Systems Inc. has developed a line of tabletop enclosures for optical tables that enable environmental isolation. Designed to be sturdy and economical, they are constructed with an aluminum...
Kinetic Systems Inc.
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Epoxy Master Bond Inc. has developed EP62-1MED, an epoxy that has improved chemical and temperature resistance. It can bond to glass optics and does not cause shrinkage. The adhesive is designed to...
Master Bond Inc.
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Microscope The H-7650 transmission electron microscope from Hitachi High-Technologies Corp. is a digital 120-kV system with a variety of high-resolution camera integration options and advanced imaging features....
Hitachi High-Tech America Inc., Life Sciences and Nanotechnology
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Spectrometry grid A method for the production of meshes or grids with a higher aspect ratio has been developed by Stork Veco BV. Its grid results in higher yields in time-of-flight/mass spectrometry processes. A...
Veco USA Inc.
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Atomic force microscopy JPK Instruments AG has released the NanoWizard II, suitable for high-resolution imaging, force spectroscopy and nanomanipulation/lithography. It has a custom-made scanning system with capacitive...
Bruker Nano GmbH, JPK BioAFM
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Power meters Newport Corp. has unveiled the 1931-C and 2931-C optical power meters for measuring any type of laser, laser diode or broadband light source. The instruments can make power measurements from 10 pW to...
MKS/Newport
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Binocular magnifiers Suitable for working with lasers on small areas in medical or micromachining applications, binocular magnifiers with laser protective filters have been introduced by LaserVision GmbH. The binoculars...
LASERVISION GmbH & Co. KG
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Microscope controller Prior Scientific Inc. has released the ES10 OptiScan II microscope controller with a USB connection. It contains an upgraded drive circuitry that operates more quietly than the previous-generation...
Prior Scientific Inc.
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Translation stage PI (Physik Instrumente) LP has developed a P-652 piezoelectric linear-motor-driven translation stage that produces resolution of better than 0.1 μm. It contains a vacuum-compatible, nonmagnetic,...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Software inspector Media Cybernetics Inc. has released the 3D Surface Inspector, an inspection module for Image-Pro Plus software. The module uses a Z-stack of images, which enables users to visualize and measure...
Media Cybernetics Inc.
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Imaging nanoparticles The NTA 3.1 nanoparticle characterization system from NanoSight Ltd. provides accurate images of individual nanoscale particles in suspension. Users can obtain independent quantitative estimates of...
NanoSight Ltd.
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750-nm SLEDs Exalos AG has released a line of 750-nm superluminescent light-emitting diodes (SLEDs) that can be used for optical coherence tomography and sensor applications. The products include the...
Exalos AG
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Microscopy software For microscopic enzyme-linked immunospot examinations in tumor, AIDS and vaccine research and in the routine lab, Carl Zeiss MicroImaging GmbH has announced the KS Elispot and compact KS Elispot 4.9...
Carl Zeiss Microscopy LLC
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Ti:sapphire oscillator The Mira HP ultrafast Ti:sapphire oscillator from Coherent Inc. is specified to generate more than 3.3 W of output power, while typically delivering more than 4 W at 800 nm. Designed to be pumped by...
Coherent Inc.
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CW lasers Spectra-Physics, a division of Newport Corp., has enhanced its Excelsior family of diode-pumped solid-state and direct diode lasers with the release of low-power, continuous-wave models at 375, 405,...
Newport Spectra-Physics GmbH, Photonics Solutions Div.
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Laser module Available from Snake Creek Lasers LLC, the thermally stabilized MiniModule-OEM-1 MiniGreen laser module is designed to facilitate evaluation of the MiniGreen laser, which produces 30 to 150 mW of...
Advanced Photonic Sciences LLC
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Digital systems Nikon USA has added the DS-Fi1 digital camera head and the DS-L2 and DS-U2 control units to its Digital Sight series. The camera head, with a CCD sensor, offers 5-megapixel resolution and faster...
Nikon Instruments Inc.
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Scanning probe Nanonics Imaging Ltd. has unveiled the MV4000 scanning probe microscope, which can accommodate up to four probes. The microscope’s 3D FlatScanner piezoelectric scanning stage enables an X-Y...
Nanonics Imaging Ltd.
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Confocal microscope The TCS SPE confocal microscope system from Leica Microsystems employs an ultrahigh dynamic PMT detector and four solid-state lasers with wavelengths of 405, 488, 532 and 635 nm. It offers...
Leica Microsystems
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Cell accelerator board Mercury Computer Systems Inc. has unveiled its Mercury Cell Accelerator Board, providing cell technology for commercially available PC workstations. The board, based on the company’s Cell...
Mercury Systems Inc.
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BIOPHOTONICS 2006
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