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BioPhotonics: July 2008

BioPhotonics
 July 2008


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FEATURES
Focused Molecular Imaging Using Radiotracers Locating, imaging and quantifying concentrations of specified molecules deep within the body are essential in medicine and in drug discovery and development. Together often called molecular imaging, these tasks typically are performed by attaching radioactive atoms, or radiotracers, to the molecules and observing the radiation externally. Another molecular imaging modality uses fluorescent...
Getting in Deeper Thanks to microendoscopic research and technology innovations, patients could be in for a new set of close-ups. Several groups of investigators are working to implement optical biopsies, in which the...
Prospects for Photodynamic Therapy in Dentistry Photodynamic therapy (PDT) involves the use of a photosensitizer that is activated by illumination in the presence of oxygen. The exposure of the photosensitizer to light results in the formation of...
POST SCRIPTS
Microscope reveals ‘Nutcracker Man’ may not live up to his name Half a century ago, scientists uncovered the 1.2- to 2.3-million-year-old bones of Paranthropus boisei in eastern Africa. It had the flattest cheek teeth and thickest enamel of any known human ancestor. The size and shape of the teeth, jaws and cranium led the scientists to conclude that P. boisei ate hard and brittle foods such as nuts, seeds, roots and tubers. Thus, P. boisei became known...
AS WE GO TO PRESS
Automated MRI technique could expedite Alzheimer’s diagnosis An automated system to measure brain tissue volume with MRI has shown promise as a tool for the rapid and accurate diagnosis of Alzheimer’s disease at an earlier stage, according to a study conducted...
Optical trap technique measures single-molecule forces The molecular mechanics of the cell are a frontier that scientists still are striving to learn more about. For example, the cell’s cytoskeleton — which provides structural integrity — is of interest...
New method can create fluidic channels with unusual shapes Most micro- and nanofluidic chips contain channels with flat rectangular sides. A novel technique called “nanoglassblowing” can create curved micro- and nanochannels from glass, including funnels...
A femtosecond laser can be a pacemaker for heart muscle cells Femtosecond lasers are used in applications as diverse as optical microscopy and lasik eye surgery. Now scientists at Osaka University in Japan have discovered that femtosecond laser pulses can cause...
BREAKTHROUGHMEDIA
Technical support AnaSpec Inc. has extended its online technical support with the addition of a keyword search function for its Frequently Asked Questions section, which is now organized by category. It enables users to more quickly and conveniently find information in the FAQ database of possible solutions. A keyword search returns a list of results sorted by relevance. The question categories are peptides,...
Optics resource Anchor Optics’ Spring 2008 catalog of optics for industry, research and education features new commercial-grade large planoconvex condenser lenses, achromats, corner cubes, cube and elliptical...
Antibodies A brochure titled “Antibodies Validated for Flow Cytometry” from Cell Signaling Technology Inc. details a selection of Alexa Fluor conjugated antibodies, and it includes sections on immunology and...
OCT microscope Michelson Diagnostics Ltd. has released a brochure on its high-resolution EX1301 OCT (optical coherence tomography) microscope for clinical research applications. Downloadable from the company’s Web...
Life sciences research A provider of life sciences technologies for research, production and diagnostics, Invitrogen Corp. has launched a Web site designed to offer its customers an easier and more rapid way to locate,...
Flow cytometry A supplier of benchtop cell analysis systems, Guava Technologies Inc. has redesigned its corporate Web site to focus on its main end-user groups: life scientists, flow cytometrists and clinicians....
Antibody resource Millipore Corp. has launched the Antibody Learning Center, an online tool to help scientists navigate its antibody portfolio and plan work flows for immunodetection in specific focus areas of protein...
PRODUCTS
Laser dichroics The BrightLine laser dichroics from Semrock Inc. are suitable for laser-based fluorescence microscopy. The 45° beamsplitters are optimized for lasers typically used in fluorescence imaging, including...
IDEX Health & Science - Semrock Optical Filters
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Optical modeling software Lambda Research Corp. has unveiled the TracePro 5.0 software for optical modeling, design and analysis. This version delivers enhanced light source modeling, enabling users to combine multiple light...
Lambda Research Corp.
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594-nm laser The Excelsior 594 laser has been released by Newport Corp.’s Spectra-Physics Lasers Div. The twelfth addition to the Excelsior OEM family of low-power CW lasers, the multilongitudinal-mode device...
Newport Corporation
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Imaging chamber Designed for the CytoViva imaging system, the CV-30 live-cell imaging chamber from Warner Instruments is compatible with microscope stages that accept multiwell plates as well as those that have a...
Warner Instruments LLC
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Sequencing software CLC bio has unveiled the CLC Genomics Workbench software that can analyze and visualize data from all major next-generation sequencing platforms, such as Solid from Applied Biosystems, 454 GS flx...
CLC bio USA
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Linear motor slide The P-653 piezo motor linear slide from PI (Physik Instrumente) LP is a four-part true linear motor device with an operating speed of up to 200 mm/s. It is 8 mm long, with a travel range of 2 mm,...
PI (Physik Instrumente) LP, Air Bearings and Piezo Precision Motion
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Anti-actin antibodies AnaSpec Inc. has unveiled a suite of anti-actin antibodies with labeling options including biotin and fluorescent and proprietary HiLyte dyes. Also available unlabeled, they are made from rabbit...
AnaSpec
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NIR spectrometer The ARCSpectro-NIR series from Arcoptix SA is a miniature Fourier transform spectrometer based on microelectromechanical system scanning technology. The fiber-based device operates with a single...
ARCoptix SA
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Spectral irradiance meter B&W Tek Inc.’s BSR112E series miniature spectral irradiance meter was designed for use in field, industrial and laboratory applications, including solar studies, photobiology and photochemistry....
B&W Tek
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Data acquisition system Available from Vertilon Corp., the PhotoniQ IQSP582 has applications in positron emission tomography, single-photon-emission computed tomography and high-energy particle physics. The 64-channel data...
Vertilon Corp.
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Wide-field systems The Leica Advanced Widefield Systems from Leica Microsystems GmbH were designed for wide-field fluorescence microscopy. The AF6000 E, AF6000, AF6500 and AF7000 all use the same software platform and...
Leica Microsystems GmbH
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Specimen harvesting Carl Zeiss MicroImaging GmbH has introduced the SlideCollector 48 for its laser microdissection systems. The collector is compatible with the Palm MicroBeam and the Palm CombiSystem, and it enables...
Carl Zeiss Spectroscopy GmbH
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Light pipes Docter Optics GmbH has introduced miniature light pipes made of optical glass for use in LED applications and laser-based systems. The free-form lenses have a diameter of 2 to 3 mm and are 8 to 10 mm...
Docter Optics SE
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Terahertz laser Toptica Photonics AG has unveiled a frequency control package for the generation of continuous wave terahertz radiation based on distributed feedback (DFB) diode technology. The system has a tuning...
Toptica Photonics AG
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Tabletop TCSPC Becker & Hickl GmbH has introduced Simple-Tau 154, a tabletop time-correlated single-photon-counting (TCSPC) system with two or four channels and a time-channel width down to 813 fs. It operates...
Becker & Hickl GmbH
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Imaging System Toshiba Imaging Systems Div. has partnered with Olympus Canada to offer the high-definition Synergy-HD microscope imaging system, a tool for clinical pathology and teaching. Toshiba’s...
Toshiba Imaging Systems
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Multispectral cameras FluxData Inc. has released the FD-1665 series three-CCD cameras, available in 1.4-, 2- and 5-megapixel resolutions using Sony ICX-285, -274 and -625 CCDs, respectively. Users can choose a...
FluxData Inc.
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Color LCDs Richardson Electronics has introduced Image Systems’ high bright color LCD series for medical imaging. Available in two versions, the FP2202CHBP offers 2 megapixels, a contrast ratio of 500:1 and...
Richardson Electronics Ltd.
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Microscope illuminator DiCon Fiberoptics Inc. has expanded its family of LED illuminators with the tunable LED illuminators model, a compact solution for microscopy applications. It offers a tunable range of white or...
DiCon Fiberoptics Inc.
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Array plates Incom Inc. has introduced custom-made microcapillary array plates for a variety of analysis, sensing and processing functions. The plates are available in large-area-format wafers (15 × 10 in.) that...
Incom Inc.
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Diode laser The HB-Diode diode laser system from Coherent Inc. delivers 75 W of power at either 808 nm from a 200-μm-core 0.22-NA fiber, or at 976 nm from a 400-μm-core 0.22-NA fiber. The fully...
Coherent Inc.
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Fluorescence detector Shimadzu Scientific Instruments Inc. has unveiled the MCE-202 MultiNA fully automated microchip-based capillary electrophoresis analyzer for high-speed analysis of DNA and RNA samples. The analyzer...
Shimadzu Scientific Instruments Inc.
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Illumination system Olympus Life Science Europa GmbH has added the Optigrid M structured illumination system to its life sciences microscopy range. Compatible with the company’s BX2, IX2 and MVX10 microscopes, it yields...
Olympus Europa SE & Co. KG, Medical Systems & Micro-Imaging Solutions Group
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Diode lasers The Compact 200/200 fiber-coupled diode laser system from Dilas delivers 200 W of cladding-free optical power at 200 μm and is a suitable source for fiber laser pumping. The Compact series is...
DILAS Diode Laser Inc.
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UV-curable adhesive UV10MED, a one-component, low-viscosity, optically clear UV-curable adhesive, is available from Master Bond Inc. The compound is USP Class VI-approved and is recommended for use in medical device...
Master Bond Inc.
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Nanosphere conjugates Carestream Molecular Imaging has added nanosphere conjugates labeled with streptavidin to its Kodak X-Sight family. These optical molecular imaging agents enable the detection of biotinylated probes...
Carestream Health, Molecular Imaging
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Touch-screen display The Radiance 52-in. wall-mounted touch-screen display from NDS Surgical Imaging is a comprehensive visualization system for use during minimally invasive surgery and interventional procedures. It can...
NDS Surgical Imaging LLC
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Medical device adhesive Available from Dymax Corp., the MD 1162-M medical device adhesive is a fluorescing light-curing substance for bonding needles, syringes and other stainless steel cannulas. It has low viscosity for...
Dymax Corp.
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BIOPHOTONICS 2008
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