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BioPhotonics - July 2006


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Spectral Confocal Microscopy Aids FRET Studies FRET is an energy transfer between two fluorescent molecules that occurs without the exchange of a photon. It occurs when a fluorescent molecule, usually called the donor probe, is excited by the absorption of a photon. If a fluorescent probe that can be excited by the energy held in the excited state of the donor molecule is very near, resonance energy transfer can occur between the molecules....
Resolution of Optical Microscope Redefined Optical microscopy is an important tool for studying live biological cells in life sciences research, enabling the observation of various biological processes in real time. The study of nanoscale...
Medical Imaging Learns from Computer Gaming Medical imaging systems such as CT, MRI and ultrasound are becoming ubiquitous. As the technology becomes more commonplace, it also continues to mature. Significant imaging applications arise each...
RapidScan
Virtual histology method bolsters visualization of mouse embryos iologists use gene targeting in mice to further understand the causes of birth defects and childhood cancer. However, the technique they use entails careful and tedious histological sectioning of...
Nanowires function as tiny light sources Researchers from the National Institute of Standards and Technology in Boulder, Colo., have produced nanowires in gallium nitride and related alloys that may potentially find use as nanoscale lasers...
Thin-film device may provide a sense of touch for minimally invasive surgery Doctors have reported that minimally invasive surgery suffers from a lack of the sense of touch, causing frustration and even errors during these procedures. Incorporating a high-resolution sensor...
Carbon-based nanomaterials display size-dependent toxicity Carbon-based nanomaterials are becoming more prominent in a variety of nanotechnology applications; for example, as contrast agent transporters for imaging. The growing use of these materials will...
Brain folds virtually unfolded to study brain disorder A computerized brain atlas has enabled scientists to study brain structure changes in subjects who have Williams syndrome. This unusual developmental disorder impairs visual, spatial and...
An alternative to reading glasses A s with death and taxes, presbyopia, the inability to focus close up, is one of life’s certainties. Nearly everyone suffers from it by age 50. Reading glasses, the traditional solution, work...
Optical devices uncover how flies walk upside down In a series of experiments aimed at learning more about how flies can walk upside down, researchers at Max Planck Institute have determined that flies place their feet very carefully to keep them...
Winners announced for Imaging in Action photo contest Media Cybernetics Inc. recently announced the winners of its 2006 Imaging in Action contest. The first-place submission, by Andres Hidalgo of Mount Sinai School of Medicine in New York, was a video...
The National Science Foundation The National Science Foundation of Arlington, Va., has funded a multimillion-dollar engineering research center at Princeton University in New Jersey. The goal of the Mid-Infrared Technologies for...
Invitrogen Corp. and Signalomics GmbH Invitrogen Corp. of Carlsbad, Calif., and Signalomics GmbH of Steinfurt, Germany, have announced their collaboration to develop nanocrystal reagents to enhance tumor identification. The...
Reliant Technologies Inc. The FDA has granted clearance to Reliant Technologies Inc. of Mountain View, Calif., to market its Fraxel laser, which is used to treat scarring from acne and surgeries. The laser accomplishes this...
Biacore International AB Biacore International AB of Uppsala, Sweden, which focuses on life sciences instrumentation, has launched operations in China. The venture will employ seven people in Shanghai and others in outlying...
Aperio Technologies Inc. Aperio Technologies Inc. of Vista, Calif., has received a US patent for its data management system, designed to work with the linear-array-based slide scanner. The patent is in keeping with the...
Advanced Refractive Technologies Inc. Advanced Refractive Technologies Inc. of San Clemente, Calif., has acquired OptiMetrix Technologies Inc., a subsidiary of Utek Corp. of Plant City, Fla. OptiMetrix holds the license for fiber optic...
Mediplan GmbH Mediplan GmbH plans to invest €15 million in Retina Implant GmbH of Reutlingen, Germany, which concentrates on subretinal implants. The Wayne, N.J., company intends to withhold half of the...
The Russian Ministry of Health The Russian Ministry of Health has chosen PerkinElmer Inc. of Wellesley, Mass., to be the primary supplier of neonatal screening technologies. The ministry has announced an increase in the number of...
Applied Imaging Corp. Applied Imaging Corp. of San Jose, Calif., has been accepted to collaborate in Dismal(1), a three-year cancer research project funded by the European Union. Participating researchers aim to improve...
University of Tampere The University of Tampere in Finland and Information Society Technologies, based in Brussels, Belgium, have initiated a project, Communication by Gaze Interaction (Cogain), to make eye-tracking...
Michelson Diagnostics Ltd. Michelson Diagnostics Ltd. of Orpington, UK, has been awarded a £140,000 grant for research and development by the London Development Agency. The monies will be used to develop a prototype...
Society of Nuclear Medicine The Society of Nuclear Medicine in Reston, Va., has begun a $5 million, five-year molecular imaging project called “Bench to Bedside.” The project’s goal is to bring scientific...
Carl Zeiss SMT Inc. Carl Zeiss SMT Inc. of Thornwood, N.Y., and the California Institute for Telecommunications and Information Technology have opened the Carl Zeiss Center of Excellence on the University of California,...
Syncroscopy Syncroscopy of Cambridge, UK, has agreed to allow Leica Microsystems of Wetzlar, Germany, to integrate its Auto-Montage Pro software with Leica’s Application Suite software. The resulting...
American Medical Systems (AMS) American Medical Systems (AMS) of Minnetonka, Minn., has entered into an agreement to acquire Laserscope of San Jose, Calif. Both companies focus on men’s health, with AMS having already...
Optos PLC Optos PLC of Dunfermline, UK, has received FDA approval for its P200MA retinal imaging device. The instrument, which takes a quarter of a second to scan approximately 80 percent of the retina, is...
Chip-Man Technologies Ltd. Chip-Man Technologies Ltd. of Tampere, Finland, and TCS Cellworks of Botolph Claydon, UK, have announced a collaboration in which the former’s Cell-IQ platform will be offered with the...
Invitrogen Corp. Invitrogen Corp. of Carlsbad, Calif., has agreed to provide reagents for the genome analysis system manufactured by Solexa Inc. of Hayward, also in California. The reagents will be for the...
Olympus Olympus of Germany has just merged its subsidiaries Soft Imaging System and Olympus BioSystems into a new company, Olympus Soft Imaging Solutions GmbH. The new entity will focus on software and...
Synergetics USA Inc. Synergetics USA Inc. of O’Fallon, Mo., has signed a three-year agreement with Quantel Medical of Clermont-Ferrand, France, in which it will have distribution rights in the US and Canada to...
As We Go To Press
First photograph taken of critically endangered rhino species A type of Sumatran rhinoceros that lives in the wilds of Sabah, Malaysia, an area called the Heart of Borneo, has been photographed for the first time. Although hundreds of species of rhinos are thought to have existed prehistorically, only five are known to remain today. The photographed animal, whose existence was confirmed during a field survey last year, is a member of a subspecies of the...
Monitoring brain health in babies A recent study conducted at the Máxima Medical Center in Veldhoven, the Netherlands, has shown that, by using a diffusion tensor MRI technique, it is possible to more effectively monitor the...
Interlacing gives thin beams solid beam power Since the 1990s, researchers have been trying to replace the solid beams used in conventional radiation treatment with parallel arrays of very thin — 25 to 90 μm — planar x-ray beams....
Discoveries made in how the brain senses scent Studies have revealed that mono-molecular odors activate distinct patterns of glomeruli — bundles of olfactory receptor axons on the main olfactory bulb of the brain — and that the...
Imaging demonstrates recovery from traumatic head injury Victims of traumatic brain injury may progress through comatose, vegetative and minimally conscious states, at the end of which they only intermittently show behavioral evidence of communication or...
BreakthroughMedia
Laser safety Part of the “Optical Science and Engineering” series, Laser Safety Management is a guide for implementing laser safety programs in various environments. Authored by a laser safety...
Quantitative biology The 2006 catalog from Panomics Inc. details products for parallel quantitative biology, which the company defines as contextual, systems-level measurements of genes, proteins and their cellular...
Laser resource Melles Griot Corp. has made available for purchase online the full line of lasers presented in its “Catalog X.” The buy-online site also includes the 56 RCS series diode laser assemblies...
FRET filters Available from Omega Optical Inc. is the FRET Application Note “Optimizing Filter Sets for Fret Applications.” Downloadable from the company Web site, the four-page document begins with...
Vibration isolation Technical Manufacturing Corp. has released its “2006 General Catalog,” which features precision vibration isolation systems for sensitive research and manufacturing processes in the...
Nanopositioning The 215-page “Product Catalog 2005 & 2006” from attocube systems AG details nanopositioners for applications such as sample positioning in scanning probe microscopy. It presents...
Breast imaging The 1008-page Recent Advances in Breast Imaging, Mammography, and Computer-Aided Diagnosis of Breast Cancer discusses the anatomic, histopathologic and mammographic views of the breast and the...
Nanotechnology market The 235-page Nanotechnology Applications and Markets provides an analysis of the market to help professionals forecast the impact of the technology on a company. It presents technical, business and...
Stem cell products The full-color, 45-page catalog “BD Biosciences Stem Cell Source — from isolation to analysis,” published by BD Biosciences, provides an overview of the company’s products for...
Microarray research The spring 2006 issue of the quarterly review Affymetrix Microarray Bulletin focuses on advances in cancer research. Published by Affymetrix Inc., the downloadable 27-page document features an...
Postscripts
Watch that stinger, if you can... One of the fastest biological processes known to man — that of the jellyfish sting — now has been captured on camera. Thomas W. Holstein and his colleagues at the University of Heidelberg in Germany recently recorded the phenomenon. Organisms in the phylum Cnidaria have nematocysts, or stingers, that contain a mixture of hemolytic and neurotoxic poisons. The toxins can be discharged...
Products
Quantitative imaging The Abrio imaging system from Cambridge Research & Instrumentation Inc. allows researchers to observe living cells noninvasively and in detail using intrinsic contrast within the intact cell. It...
PerkinElmer (See Revvity)
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Digital cameras Available from Diagnostic Instruments Inc., the Spot RT3 monochrome digital camera features FireWire connectivity and is suitable for bright-field and fluorescence imaging applications. It has a 1600...
SPOT Imaging
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Laser filters Tailored for 405-, 440-, 470- and 635-nm commercially available diode lasers, the MaxDiode cleanup filters offer 90% transmission over a defined range of each diode’s expected wavelengths....
IDEX Health & Science - Semrock Optical Filters
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Three-CCD microscope camera Optronics has launched Microcast, a digital three-CCD camera designed for installation on surgical microscopes. The medical-grade megapixel camera system provides real-time, 36-bit RGB image...
Optronics
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UV camcorder The UVCorder digital camcorder is designed for viewing scenes in the near-UV waveband in real time on a 3.5-in. LCD. Oculus Photonics LLP’s device is equipped with the Sony Intelligent...
Oculus Photonics
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Optical blocks Seven types of optical blocks for use with photomultiplier tube modules are available from Hamamatsu Corp. The compact devices can be combined to meet the specifications of various applications. The...
Hamamatsu Corporation
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Erbium fiber A highly doped erbium double-clad large-mode-area fiber for applications in the 1.5- through 1.6-μm wavelength range has been introduced by Liekki Corp. Suitable for medical imaging and eye-safe...
nLIGHT Inc.
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CCD camera Designed for capturing low-level fluorescence images, the DQC-FS electron-multiplying CCD monochrome digital camera is suitable for applications such as single-molecule fluorescence, high-speed...
Nikon Instruments Inc.
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Nanopositioning The E-761 piezoelectric controller from PI (Physik Instrumente) LP features PCI-bus connectivity that enables high-resolution vision, precise synchronization between components, and high-speed motion...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Digital camera Dage-MTI Technologies has launched a 2048 x 2048-pixel 12-bit FireWire digital camera. The XLM, based on Kodak’s KAI-4021M progressive-scan interline sensor, has good quantum efficiency and...
Dage-MTI of Michigan City Inc.
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Data visualization Version 6.0 of Open Inventor from Mercury Computer Systems Inc. is an object-oriented, cross-platform tool kit for developing 3-D interactive graphics applications. Suitable for medical...
Mercury Systems Inc.
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FTIR spectrometer The Vertex 80v benchtop vacuum Fourier transform infrared (FTIR) spectrometer from Bruker Optics Inc. features the Bruker artificial intelligence network, automatic optical component and accessory...
Bruker Optics Inc.
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Objective positioning The Mipos 100 PL is an enhanced piezoelectric objective lens-positioning system from piezosystem jena GmbH. Applicable in standard and in inverse microscopy, the PL replaces the...
piezosystem jena GmbH
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Thin-film software Semiconsoft Inc. has launched version 3.0 of its TFCompanion software for thin-film data analysis in biotechnology applications. The upgrade provides imaging ellipsometry/reflectometry data analysis...
Semiconsoft Inc.
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Avalanche photodiodes Voxtel Inc. has introduced a collection of avalanche photodiodes (APD) for high-bandwidth, near-infrared optical applications. The devices feature a spectral response from 0.9 to 1.7 μm and low...
Voxtel Inc.
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FO spectrometer The AvaSpec-3648 fiber optic spectrometer from Avantes Inc. is suitable for measurements in high-speed and high-resolution applications, such as laser-induced breakdown spectroscopy and pulsed-light...
Avantes USA
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Laser mirrors Alpine Research Optics Corp. has announced a series of flat mirrors for general-purpose beam steering in applications based on UV excimer lasers such as microlithography and lasik. The company says...
Alpine Research Optics
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LED dimmer A variable LED dimmer for use with condensers, lenses that have coaxial surface illumination and other LEDs with current limiting and consumption between 50 and 450 mA is being offered by Sill Optics...
Sill Optics
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Fiber stripper The All-Strip fiber stripper from FiberLogix Ltd. removes polyimide and other coatings without the use of hot acid. It accommodates a variety of fiber sizes up to 1 mm in thickness for window or end...
FiberLogix International Ltd.
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FPGA developer’s kit Designed for directly coding the field-programmable gate arrays (FPGAs) that are part of the company’s hardware products, Matrox Imaging has released the Matrox FPGA Developer’s Kit. The...
Matrox Imaging
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Translation stage Standa has produced the 7T34-20, a nonmagnetic translation stage that can be assembled into an X-Y or X-Y-Z configuration directly, without additional elements. The device has a travel range of 20 mm...
STANDA UAB
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Phase-only modulator Holoeye Photonics AG has unveiled the HEO 1080 P phase-only spatial light modulator. Based on a reflective liquid-crystal-on-silicon microdisplay, the device provides 1920 x 1080-pixel resolution in...
HOLOEYE Photonics AG
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Microscope camera The DP71 progressive-scan CCD camera from Olympus Life and Material Science Europa GmbH is suitable for microscopic bright-field and fluorescence imaging applications such as pathology. In live mode,...
Olympus Europa SE & Co. KG
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Beam profiler software Coherent Inc. has announced the release of version 4.3.1 of BeamView-USB for its LaserCam-HR beam profiler system. The updated software features an improved interface that enhances ease of use,...
Coherent Inc.
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Multipass amplifier The Femtopower compact Pro CE-Phase is a multipass Ti:sapphire amplifier from Femtolasers Productions GmbH that employs a sealed vacuum chamber system for the amplifier crystal and dispersive mirror...
Spectra-Physics Vienna
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Far-UV detector The Rod-360-UV18 detector manufactured by Gigahertz-Optik Inc. is designed to measure the effective ultraviolet germicidal irradiance used in air and water sterilization applications that employ low-...
Gigahertz-Optik Inc.
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Cube beamsplitter Designed for 532- or 1064-nm Nd:YAG lasers, Tech Spec polarizing cube beamsplitters from Edmund Optics feature a precision fused silica substrate and high-energy coatings. They use multilayer...
Edmund Optics
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Imaging spectrograph The prealigned Shamrock 163i spectrograph from Andor Technology plc is based on a Czerny-Turner optical layout and features a 163-mm focal length, an entrance aperture ratio of f/3.6 and a wavelength...
Oxford Instruments
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Surface analysis The SensoMap micro- and nanosurface analysis software from Digital Surf Sarl has been developed for use with the PLμ confocal and the PLμ 2300 optical imaging profilers produced by...
Digital Surf
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Light source The SIL 500 Joule multiheaded xenon flashlamp from Specialised Imaging Ltd. is designed for use with ultrafast cameras that have short recording times. The device generates high-intensity...
Specialised Imaging Inc.
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